Journal
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Volume 215, Issue -, Pages 47-57Publisher
ELSEVIER
DOI: 10.1016/j.molbiopara.2016.12.001
Keywords
Helminths; Glycans; Mass spectrometry; Glycan array; Glycan antigen; Schistosome
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Glycoproteins and glycolipids of parasitic helminths play important roles in biology and host-parasite interaction. This review discusses recent helminth glycomics studies that have been expanding our insights into the glycan repertoire of helminths. Structural data are integrated with biological and immunological observations to highlight how glycomics advances our understanding of the critical roles that glycans and glycan motifs play in helminth infection biology. Prospects and challenges in helminth glycomics and glycobiology are discussed. (C) 2016 Elsevier B.V. All rights reserved.
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