Review
Immunology
Karina L. Hissen, Wenliang He, Guoyao Wu, Michael F. Criscitiello
Summary: Comparative animal models provide fundamental scientific knowledge of immune responses. There is now an interest in using teleost fish models to study intestinal immunology, with a focus on the intestinal mucosa immune response. Amino acid supplementation can enhance the immune response in fish, and nutritionists can develop sustainable aquafeeds to promote specific immune responses. To further understand the mucosal immune system in fish, future studies should incorporate various tools such as genomics, proteomics, nutrition, immunology, and metabonomics analysis.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Agnieszka Wolnicka-Glubisz, Anna Wisniewska-Becker
Summary: Curcumin, a natural polyphenol with antioxidant properties, can have therapeutic effects on different disorders. However, it can also be toxic under certain conditions, such as exposure to blue light or excessive use.
Article
Food Science & Technology
Junior Bernardo Molina-Hernandez, Filippo Capelli, Romolo Laurita, Silvia Tappi, Jessica Laika, Luisa Gioia, Luca Valbonetti, Clemencia Chaves-Lopez
Summary: This study evaluated the potential of cold atmospheric plasma (CAP) for microbial inactivation on food surfaces. The results showed that high power CAP was more effective in eliminating molds, inducing cell death through oxidative stress-dependent reactions. In addition, the molds exhibited adaptive mechanisms to counteract the stress caused by CAP.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2022)
Article
Plant Sciences
Kamolchanok Umnajkitikorn, Mitsutaka Fukudome, Toshiki Uchiumi, Neung Teaumroong
Summary: The study demonstrates that elevated nitrogen levels can mitigate nitrogen limitation under water deficit conditions, using nitric oxide accumulation to enhance plant tolerance. This activation of the antioxidant defense system supports improved water deficit tolerance in rice plants.
Article
Plant Sciences
Xuping Lu, Weifang Min, Yafei Shi, Lei Tian, Peifu Li, Tianli Ma, Yinxia Zhang, Chengke Luo
Summary: In this study, the effects of exogenous melatonin on rice seedlings under alkaline stress were analyzed. It was found that melatonin can enhance antioxidant enzyme activity, protect cell membranes, and increase chlorophyll content, thereby alleviating the damage caused by alkaline stress on rice.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Nutrition & Dietetics
Kosar Valaei, Shima Taherkhani, Hamid Arazi, Katsuhiko Suzuki
Summary: Reactive oxygen species (ROS) play a crucial role in the pathophysiology of cardiac diseases, leading to cellular and molecular disorders that can result in heart dysfunction. New experimental treatments such as creatine supplementation, omega-3 fatty acids, and others have shown beneficial effects in improving oxidative stress.
Review
Biochemistry & Molecular Biology
Katarzyna Dziabowska-Grabias, Malgorzata Sztanke, Przemyslaw Zajac, Michal Celejewski, Katarzyna Kurek, Stanislaw Szkutnicki, Patryk Korga, Wlodzimierz Bulikowski, Krzysztof Sztanke
Summary: Inflammatory bowel diseases (IBD) are chronic, incurable diseases of the digestive tract with unclear etiology, resulting in significant impact on patients' quality of life. The incidence and prevalence of IBD are continuously increasing worldwide, becoming a significant public health burden. Current pharmaceutical management options often have side effects and may not provide sufficient disease control, leading to research on antioxidant and anti-inflammatory substances as potential treatment options.
Article
Biochemistry & Molecular Biology
Yasuko Sakihama, Takashi Kato, Sopanat Sawatdee, Yo Yakushi, Junichi Asano, Hiroyo Hayashi, Yuya Goto, Makoto Hashimoto, Yasuyuki Hashidoko
Summary: This study successfully isolated highly purified betanin from red beetroots using an improved purification method and demonstrated its strong antioxidant activity and cytoprotective effects against ONOO- toxicity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Deyamira Matuz-Mares, Hector Riveros-Rosas, Maria Magdalena Vilchis-Landeros, Hector Vazquez-Meza
Summary: Cardiovascular diseases result in high mortality rates globally, with oxidative stress playing a key role in worsening patient conditions. Reactive oxygen and nitrogen species are generated during the development of these diseases, contributing to the deleterious effects on patients.
Article
Biochemistry & Molecular Biology
Sina Bader, Julia Wilmers, Martin Pelzer, Verena Jendrossek, Justine Rudner
Summary: DHA enhances oxidative stress and improves the efficacy of radiotherapy, but careful consideration of treatment schedule is necessary, especially in Keap1 wildtype cells.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Review
Cell Biology
Sheikh Bilal Ahmad, Aarif Ali, Midhat Bilal, Shahzada Mudasir Rashid, Amir Bashir Wani, Rahil Razak Bhat, Muneeb U. Rehman
Summary: Melatonin is a widely distributed molecule in nature and is produced by various organisms. It acts through melatonin receptors to regulate sleep and circadian rhythms. Melatonin also has antioxidant and anti-inflammatory properties, playing important roles in diseases such as cancer and neurodegenerative disorders.
CELLULAR AND MOLECULAR NEUROBIOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Jingnan Zhao, Fanfan Guo, Lin Hou, Yongxing Zhao, Pengchao Sun
Summary: Inflammatory diseases are associated with high levels of ROS. Excess ROS leads to the polarization of microphages into the proinflammatory M1 phenotype and causes damage to DNA, proteins, and lipids, worsening the inflammatory response. Scavenging ROS to alleviate oxidative stress has proven to be an effective strategy for reversing inflammation. Inspired by natural antioxidant enzymes, electron transfer-based artificial antioxidant nanozymes have emerged as therapeutic agents for treating inflammatory diseases.
JOURNAL OF CONTROLLED RELEASE
(2023)
Review
Biology
Vishnu D. Rajput, Harish, Rupesh Kumar Singh, Krishan K. Verma, Lav Sharma, Francisco Roberto Quiroz-Figueroa, Mukesh Meena, Vinod Singh Gour, Tatiana Minkina, Svetlana Sushkova, Saglara Mandzhieva
Summary: Plants rely on a complex grid of antioxidant enzymes to cope with stress conditions, with SOD, CAT, POX, and GPX playing crucial roles in minimizing reactive oxygen species. The interplay of these enzymes is essential for plant health and development, and their manipulation can be useful in developing stress-tolerant transgenic plants.
Review
Pharmacology & Pharmacy
Sara Dabbaghi Varnousfaderani, Vali Musazadeh, Faezeh Ghalichi, Zeynab Kavyani, Soha Razmjouei, Amir Hossein Faghfouri, Sana Sedgh Ahrabi, Seyyed Morteza Seyyed Shoura, Parvin Dehghan
Summary: Through a comprehensive meta-analysis, it was found that CoQ10 has a positive effect on oxidative stress and inflammation markers. However, some studies have shown contradictory results. CoQ10 supplementation significantly reduced serum CRP and MDA levels, while increasing TAC and SOD activity. However, it did not have a significant reducing effect on TNF-α and IL-6 levels.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Cell Biology
Nikita N. Chukavin, Vladimir K. Ivanov, Anton L. Popov
Summary: This study investigated a new type of cerium oxide nanoparticles that can monitor intracellular reactive oxygen species (ROS) activity by releasing fluorescent dye calcein. The results show that these nanoparticles have selective cytotoxicity against cancer cells and can modulate the expression of key genes related to cell redox status and proliferation/migration activity.
Article
Food Science & Technology
Basil H. Aboul-Enein, Joshua Bernstein, Joanna Kruk
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2019)
Article
Biochemistry & Molecular Biology
Joanna Kruk, Hassan Y. Aboul-Enein, Aleksandra Kladna, Jacquelyn E. Bowser
FREE RADICAL RESEARCH
(2019)
Review
Biochemistry & Molecular Biology
Joanna Kruk, Katarzyna Kotarska, Basil H. Aboul-Enein
FREE RADICAL RESEARCH
(2020)
Review
Physiology
Joanna Kruk, Basil Hassan Aboul-Enein, Ewa Duchnik
Summary: Melatonin possesses antioxidant and anti-inflammatory actions, influenced by physical exercise, and beneficial for athletes.
JOURNAL OF PHYSIOLOGICAL SCIENCES
(2021)
Review
Oncology
Shahla Ostovar, Amir Modarresi Chahardehi, Intan Hashimah Mohd Hashim, Azizah Othman, Joanna Kruk, Mark D. Griffiths
Summary: Psychological distress, including depression and anxiety, is common among cancer patients in the Southeast Asia (SEA) region, with higher prevalence of anxiety than depression. The prevalence rate of psychological distress among cancer patients in the SEA region is not significantly different from that of the general population. These findings provide valuable insights for healthcare professionals and cancer patients to understand the negative impact of psychological distress on quality of life and health.
EUROPEAN JOURNAL OF CANCER CARE
(2022)
Review
Physiology
Joanna Kruk, Basil Hassan Aboul-Enein, Ewa Duchnik, Mariola Marchlewicz
Summary: Research has shown that polyphenols, as antioxidant supplements, can have a positive impact on oxidative stress and inflammation control during acute exercise. However, there is still debate regarding their effects on physical performance. Further studies should investigate optimal dosage, timing of supplementation, and the response and adaptations of different sports disciplines to polyphenols.
JOURNAL OF PHYSIOLOGICAL SCIENCES
(2022)
Article
Nutrition & Dietetics
Magdalena Kiedrowicz, Ewa Duchnik, Jolanta Wesolowska, Beata Bania, Malgorzata Peregud-Pogorzelska, Dominika Maciejewska-Markiewicz, Ewa Stachowska, Joanna Kruk, Mariola Marchlewicz
Summary: This study involved 60 women who received treatments for abdominal fat reduction using ultrasound, radiofrequency, or a combination of both. The treatments resulted in cosmetic effects such as weight loss and reduced waist circumference. However, there were no significant effects on lipid profile, insulin resistance markers, inflammation markers, or blood pressure, indicating that the treatments did not modify the cardiovascular disease risk.
Review
Public, Environmental & Occupational Health
Christa Corgatelli, Elizabeth Dodge, Joshua Bernstein, Joanna Kruk, Basil H. Aboul-Enein
Summary: This review evaluated evidence-based lifestyle intervention programs and found that longer duration interventions produced significant and consistent results in mediating outcomes related to prediabetes/T2DM in high-risk populations.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2022)
Review
Nutrition & Dietetics
Ewa Duchnik, Joanna Kruk, Aleksandra Tuchowska, Mariola Marchlewicz
Summary: Psoriasis is an inflammatory disease influenced by genetic factors, autoimmunity, and environmental/lifestyle factors, including nutrition and physical activity. Nutrigenomic studies have shown the impact of nutrients on modulating microRNAs, but there is limited research on the effect of nutrition and physical activity on treating psoriasis. This narrative review provides updated information on dietary recommendations for psoriasis patients and discusses the role of diet and physical activity in prevention and treatment, as well as the application of nutrigenetics in therapy.
Article
Public, Environmental & Occupational Health
Laura Coats, Basil H. Aboul-Enein, Elizabeth Dodge, Nada Benajiba, Joanna Kruk, Meghit Boumediene Khaled, Mustapha Diaf, Salah Eddine El Herrag
Summary: This thematic narrative synthesis explores the Mediterranean Diet (MDiet) and its impact on the environment, including land and water use, Greenhouse Gas emissions, fossil fuels, affordability, and acceptability. The MDiet is a sustainable dietary pattern that can improve both population health and the environment. However, factors such as diet acceptability, cost, culture, and socio-economic considerations need to be taken into account when recommending dietary patterns at the regional or global level.
JOURNAL OF HUNGER & ENVIRONMENTAL NUTRITION
(2022)
Review
Public, Environmental & Occupational Health
Lisa A. Blankinship, William A. Rouse, Joshua Bernstein, Joanna Kruk, Basil H. Aboul-Enein
Summary: Faith-based wellness programs have positive effects on Latino and African-American populations in terms of overall health, obesity management, type 2 diabetes, and hypertension. The perceived authority of faith community nurses and leaders, as well as the accountability and encouragement provided by faith communities, play a critical role in promoting long-term behavior change. Cultural appropriateness, community support, and self-efficacy are key elements that contribute to the success of faith-based organizations in promoting health and wellness.
JOURNAL OF RELIGION & HEALTH
(2021)
Article
Allergy
Ewa Duchnik, Joanna Kruk, Irena Baranowska-Bosiacka, Anna Pilutin, Romuald Maleszka, Mariola Marchlewicz
POSTEPY DERMATOLOGII I ALERGOLOGII
(2019)
Review
Health Policy & Services
Leah Qubty, Basil Aboul-Enein, Lori Bechard, Joshua Bernstein, Joanna Kruk
INTERNATIONAL JOURNAL OF HUMAN RIGHTS IN HEALTH CARE
(2019)
Article
Nutrition & Dietetics
B. H. Aboul-Enein, J. Bernstein, J. Kruk
NUTRITION BULLETIN
(2017)