Article
Chemistry, Analytical
Svetlana Dorovskikh, Darya D. Klyamer, Anastasiya D. Fedorenko, Natalia B. Morozova, Tamara Basova
Summary: This paper describes the electrochemical behavior of a modified glass carbon electrode (GCE) coated with Fe(II) tetra-tert-butyl phthalocyanine film (FePc(tBu)(4)/GCE) and decorated with gold nanoparticles (Au/FePc(tBu)(4)/GCE) for the detection and control of nitrate content in food products. The modified electrode exhibited high sensitivity, low limit of detection, good repeatability, and stability. It showed selective response to nitrite ions in the presence of interfering anions, and successfully detected nitrite ions in real meat product samples.
Article
Chemistry, Multidisciplinary
Laura Scarpetta-Pizo, Ricardo Venegas, Pablo Barrias, Karina Munoz-Becerra, Nayareth Vilches-Labbe, Francisco Mura, Ana Maria Mendez-Torres, Rodrigo Ramirez-Tagle, Alejandro Toro-Labbe, Samuel Hevia, Jose H. Zagal, Ruben Onate, Alexis Aspee, Ingrid Ponce
Summary: This study demonstrates that the chiral-induced spin selectivity effect can greatly enhance the electrocatalytic activity of iron phthalocyanine for the oxygen reduction reaction. By using chiral peptides to assemble FePc on a gold electrode surface, the handedness and length of the peptides can optimize the kinetics and thermodynamics of ORR. The D-enantiomer shows the highest electrocatalytic activity, shifting the onset potential close to the reversible potential of the O2/H2O couple.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Polymer Science
Mingliang Li, Kefeng Xie, Guozhi Wang, Jing Zheng, Yingnan Cao, Xiang Cheng, Ziwei Li, Feng Wei, Hailing Tu, Jinyao Tang
Summary: This work focuses on preparing polymeric self-assembled monolayer (SAM) sensors for detecting trace volatile nitroaromatic compound (NAC) explosives by fluorescence quenching. By utilizing a typical aggregation-induced emission (AIE) luminogen 1,1,2,2-tetraphenylethene (TPE) polymerized into PTPE to increase fluorescence intensity in the SAMs, the sensors achieved low detection limits for TNT, DNB, and NB on inorganic testing paper. The high sensitivity and stability of SAMs, along with the high fluorescence intensity and wire effect of the conjugated polymers, contribute to the success of the sensors.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Cristian Gabellini, Maria Sologan, Elena Pellizzoni, Domenico Marson, Mario Daka, Paola Franchi, Luca Bignardi, Stefano Franchi, Zbysek Posel, Alessandro Baraldi, Paolo Pengo, Marco Lucarini, Lucia Pasquato, Paola Posocco
Summary: Organic-inorganic nanomaterials are versatile platforms with wide application areas. We introduce a general methodology to identify and classify local molecular environments in self-assembled monolayer-protected gold nanoparticles (SAM-AuNPs), and explore factors influencing the number and nature of these environments. This work is important for understanding and designing hybrid nanoconstructs.
Article
Biochemistry & Molecular Biology
Zheng Wei, Xiaoping Cai, Weifeng Cui, Junping Zhang
Summary: A CA19-9 electrochemical immunosensor was developed using a self-assembled membrane modified with a gold electrode. It demonstrated good specificity, strong anti-interference ability, and high precision and accuracy. The results showed its potential application value.
Article
Chemistry, Physical
Yurong Zhao, Xuzhi Hu, Limin Zhang, Dong Wang, Stephen M. King, Sarah E. Rogers, Jiqian Wang, Jian R. Lu, Hai Xu
Summary: Controlling the dimension of nanostructures self-assembled from short peptides remains a challenge, with peptide bolaamphiphiles forming nanotubes due to the interplay between side chain structure and hydrophobicity; changes in amino acid side chain structure can significantly impact nanostructure formation, with the introduction of hydroxyl groups alleviating steric hindrance.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Nobuhle Ndebele, Tebello Nyokong
Summary: This study presents the non-covalent conjugation of carbon-based nanomaterial with tris(4-tert-butylphenoxy)-(5-phenoxylpicolinic acid) phthalocyanato cobalt (II) (CoPc). The hybrids of CoPc with graphene quantum dots (GQDs), nitrogen-doped quantum dots (NGQDs), and single-walled carbon nanotubes (SWCNTs) were successfully synthesized and characterized. The electrochemical analysis showed that the CoPc and its conjugates exhibited good nitrite detection capabilities, with sensitivities (3-28 mu A mu M-1), catalytic rate constants (1.8 x 102-5.42 x 104 M-1 s-1), and limits of detection (0.17-1.70 mu M) comparable to those in literature.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Baolin Zhao, Bastian Gothe, Arthur Groh, Thomas Schmaltz, Johannes Will, Hans-Georg Steinrueck, Tobias Unruh, Stefan Mecking, Marcus Halik
Summary: This study demonstrates the use of phosphonic acid oligomers in self-assembled monolayer field-effect transistors, showing increased mobility in devices by controlling the thiophene unit counts. X-ray techniques reveal the molecular-scale packing and order of SAMs with different chain lengths.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Rafal Zuzak, Marek Szymonski, Szymon Godlewski
Summary: Self-assembly of iron(II) phthalocyanine (FePc) molecules on a Ge(001):H surface forms monolayer islands with upright-oriented entities. Scanning tunneling spectroscopy shows a transport gap of 2.70 eV, consistent with previous reports on isolated FePc molecules. Detailed analysis reveals that single FePc molecules can be manipulated away from surface defects and isolated from the germanium surface.
BEILSTEIN JOURNAL OF NANOTECHNOLOGY
(2021)
Article
Chemistry, Physical
Jinghan Wang, Shanqing Gao, Xiao Wang, Haozhen Zhang, Xitong Ren, Juewen Liu, Feng Bai
Summary: Functional nanoparticles used as peroxidase-like catalysts have shown great potential in cancer therapy, particularly through their shape-dependent catalytic activities and accumulation at tumor sites. The manganese phthalocyanine nanocrystals synthesized in this study demonstrated high catalytic efficiency under acidic tumor-like microenvironments, leading to excellent anti-tumor effects with minimal damage to normal tissues, which highlights their promising application as nanozymes for catalytic tumor therapy.
Article
Nanoscience & Nanotechnology
Julian M. Dlugosch, Henning Seim, Achyut Bora, Takuya Kamiyama, Itai Lieberman, Falk May, Florian Mueller-Plathe, Alexei Nefedov, Saurav Prasad, Sebastian Resch, Kai Saller, Christian Seim, Maximilian Speckbacher, Frank Voges, Marc Tornow, Peer Kirsch
Summary: This article presents a prototype of a ferroelectric tunnel junction (FTJ) based on a self-assembled monolayer (SAM) of small, functional molecules. The SAM is highly uniform and thin, and exhibits reversible conductance switching. Compared to inorganic material-based FTJs, this approach using SAMs of small organic molecules allows for a higher level of functional complexity while maintaining a robust and simple fabrication process. The technology is expected to find applications in information storage and processing.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Physics, Applied
Zhongze Guo, Yong Hu
Summary: We conducted a numerical study on the magnetization behavior of self-assembled magnetite magnetic nanoparticles (MNPs) with diameters of 10 and 14 nm at room temperature using molecular dynamics simulations. The results showed that, in the absence of a magnetic field, isotropic growth of nano-sheets or nano-chains resulted in zero magnetization. Under a constant magnetic field, self-assembly occurred and the magnetization of the MNPs was found to be maximized at 0.05 T and decreased monotonically with increasing magnetic field strength. The arrangement of MNPs and their magnetic dipole orientations aligned with the magnetic field direction under weak magnetic fields, favoring the formation of long nano-belts and nano-chains. However, under strong magnetic fields, small nano-sheets and short nano-chains with different magnetic dipole orientations were formed. These results were attributed to the competition between magnetic dipole-dipole interaction and the magnetic field, with the critical separation between MNPs depending on their diameter and magnetic field strength.
APPLIED PHYSICS LETTERS
(2023)
Article
Optics
Zhengkun Wang, Haiyang Sha, Ke Yang, Yong Zhu, Jie Zhang
Summary: In this study, the plasmonic response of self-assembled monolayer silver nanoparticles was comprehensively investigated using various computational and experimental techniques. The Fano resonance and SERS application were studied, and it was found that the higher-energy antibonding mode is not only from the antibonding dipole-dipole mode, but also from the antibonding quadrupole-quadrupole mode and hybridized magnetic mode. The effects of dimer gap and size were discussed in detail, and a two coupled oscillators model was used to illustrate the mechanism of the Fano resonance.
OPTICS AND LASER TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Camila de L. Ribeiro, Jurandir R. de Souza, Marcelo A. Pereira-da-Silva, Leonardo G. Paterno
Summary: A novel NiTsPc/ION nanocomposite electrode was proposed for the detection of ethinyl estradiol, showing a wide linear range, high sensitivity, and low detection limit. The electrode exhibited excellent recovery rates and stability in various water samples and synthetic urine, attributed to its porous morphology and efficient charge transfer between ION and NiTsPc.
Article
Chemistry, Multidisciplinary
Minsu Kang, Minho Seong, Donghyuk Lee, Seong Min Kang, Moon Kyu Kwak, Hoon Eui Jeong
Summary: A programmable self-assembly strategy is developed to create highly ordered artificial nanocilia actuators using magnetic nanoparticles. The nanocilia exhibit field-responsive motion through rolling and sliding between assembled nanoparticles.
ADVANCED MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Stephen Barrett, Michele De Franco, Andrew Kellett, Eithne Dempsey, Cristina Marzano, Andrea Erxleben, Valentina Gandin, Diego Montagner
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
(2020)
Article
Chemistry, Analytical
Rodica Doaga, Timothy McCormac, Eithne Dempsey
Article
Materials Science, Multidisciplinary
Asim Mushtaq, Ruibo Zhao, Dandan Luo, Eithne Dempsey, Xiumei Wang, M. Zubair Iqbal, Xiangdong Kong
Summary: Nanoscale magnetic hydroxyapatite nanoparticles have shown great potential in various biomedical applications, especially in cancer theranostics, due to their good stability and biocompatibility. Current research is focused on the controlled fabrication and structure-property relationships, while further exploration and development are needed in areas such as cancer treatment, tissue engineering, antimicrobial activity, etc. The multifunctional capabilities of MHAp nanoparticles and their potential in hybrid nanocarriers for biomedical applications are still being actively studied and improved.
MATERIALS & DESIGN
(2021)
Article
Materials Science, Multidisciplinary
M. Zubair Iqbal, Israt Ali, Waheed S. Khan, Xiangdong Kong, Eithne Dempsey
Summary: The assembly and disassembly of gold nanoparticles involve various forces related to surfactant chemistry, which can be externally triggered for reversible effects. This review emphasizes the use of stimuli like light, pH, temperature, and magnetic fields for reversible assembly of Au NPs, discussing mechanisms and challenges in detail.
MATERIALS & DESIGN
(2021)
Article
Chemistry, Analytical
Ayman Ali Saeed, Mohammed Nooredeen Abbas, Waheed Fathi El-Hawary, Yousry Moustafa Issa, Baljit Singh
Summary: A hydrogen peroxide sensor based on core-shell gold@titanium dioxide nanoparticles and multi-walled carbon nanotubes modified electrode was developed. The sensor exhibited excellent stability and sensitivity, and was successfully tested in human serum and saliva samples.
Review
Materials Science, Multidisciplinary
Baljit Singh, Shiliang Ma, Tony O. O. Hara, Sargun Singh
Summary: Cancer, specifically prostate cancer, remains a significant challenge despite advances in detection methods, therapeutic agents, and biomarkers. This article reviews recent achievements in utilizing nanomaterials and nanotechnology for the development of biosensors targeting various biomarkers, including prostate-specific antigen (PSA), sarcosine oxidase, prostate cancer antigen 3 (PCA3), vascular endothelial growth factor (VEGF), and prostate-specific membrane antigen (PSMA). The integration of nanotechnology and different biomarkers is providing insights into the development of biosensors for prostate cancer diagnostics.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Review
Chemistry, Analytical
Baljit Singh, Abhijnan Bhat, Lesa Dutta, Kumari Riya Pati, Yaroslav Korpan, Isha Dahiya
Summary: Antibiotics have developed resistance due to excessive use, leading to environmental pollution and health risks. Electrochemical biosensors are considered as a cost-effective, rapid, and portable alternative for antibiotic detection.
Review
Chemistry, Analytical
Zina Fredj, Baljit Singh, Mohamed Bahri, Peiwu Qin, Mohamad Sawan
Summary: Neurotransmitters (NTs) play a crucial role in regulating the functions of the nervous system and imbalances in their concentrations are linked to various neurological and psychotic disorders. Electrochemical biosensors, particularly those utilizing enzymes as recognition elements, have shown great potential for rapid and sensitive detection of NTs. This review highlights recent advances in enzymatic electrochemical biosensors for NTs detection, covering electrode materials, electroanalytical techniques, and applications in complex matrices and in vivo monitoring. Challenges and future prospects for the development of enzyme-based electrochemical biosensors for NTs detection are also discussed.
Review
Engineering, Environmental
Abhijnan Bhat, Tony O. Hara, Furong Tian, Baljit Singh
Summary: This article provides an overview of various analytical techniques for arsenic determination in drinking water, and will enhance awareness and appreciation of their role in informing and protecting our environment and water resources, globally.
ENVIRONMENTAL SCIENCE-ADVANCES
(2023)
Article
Chemistry, Analytical
Dhouha Jemmeli, Cherif Dridi, Mohammed N. Abbas, Eithne Dempsey
Summary: A sensor for detecting bisphenol A (BPA) was developed by incorporating a new compound and evaluating the sensor's analytical performance under various conditions. The sensor showed a wide linear range and low detection limit, indicating its potential for detecting BPA in milk samples.
ANALYTICAL METHODS
(2021)
Article
Biotechnology & Applied Microbiology
Grace Halpin, Karen Herdman, Eithne Dempsey
Summary: The study successfully developed a lactate biosensor using chitosan and a crosslinker, optimizing the linear range, sensitivity, and detection limit for lactate. By utilizing graphite ink as an underlying conductive layer for LOx enzyme immobilisation, the detection performance was further enhanced.
SENSORS AND ACTUATORS REPORTS
(2021)
Review
Environmental Sciences
Tony O. Hara, Baljit Singh
Summary: This review highlights the progress made in the development of electrochemical biosensors for environmental toxicants (such as pesticides and heavy metals) over the past seven years. Emphasizing the importance of developing rapid, reliable, and sensitive analytical detection systems, the review discusses current challenges and potential directions for future research.
Article
Chemistry, Analytical
Camilo Menezes, Irene Malo-Estepa, Dayle Johnston, Aoife Delaney, Mark Crowe, Michael Diskin, Eithne Dempsey
Article
Electrochemistry
Brian Murphy, Baljit Singh, Aoife Delaney, Susan Warren, Eithne Dempsey
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2020)