Article
Biochemical Research Methods
Cecilia Trivellin, Lisbeth Olsson, Peter Rugbjerg
Summary: Stable cell performance in a fluctuating environment is crucial for sustainable bioproduction and synthetic cell functionality. This study introduces a high-throughput strategy for quantifying the robustness of multiple cellular functions and strains in a perturbation space. The findings suggest that robustness is function-specific and characterized by positive and negative function-specific trade-offs.
ACS SYNTHETIC BIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Pattanan Songdech, Rawitsara Intasit, Yodying Yingchutrakul, Chutikarn Butkinaree, Khanok Ratanakhanokchai, Nitnipa Soontorngun
Summary: The transcription factor Znf1 plays a key role in activating cryptic xylose metabolism in yeast for xylitol production. Overexpression of ZNF1 and the absence of the xylose suppressor bud21 Delta can significantly increase xylitol production and improve tolerance to lignocellulosic inhibitors. This study highlights the potential application of Znf1 and Bud21 in enhancing xylose utilization for sustainable lignocellulose-based bioeconomy with a generally recognised as safe yeast.
MICROBIAL CELL FACTORIES
(2022)
Article
Agricultural Engineering
Fanny Machado Jofre, Andres Felipe Hernandez-Perez, Julio Cesar dos Santos, Maria das Gracas de Almeida Felipe
Summary: The study proposed a new approach for detoxifying hemicellulosic hydrolysates using residual dry yeast biomass, and found that detoxified products showed good performance in xylitol production.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Review
Energy & Fuels
Vasundhara Jain, Sanjoy Ghosh
Summary: Lignocellulosic biomass is a significant renewable energy source, consisting mainly of cellulose, hemicellulose, and lignin, which can be transformed into valuable chemical products. Xylitol, a high-value product derived from lignocellulosic biomass, currently produced chemically, has the potential for biotechnological production to reduce costs and utilize waste. Advances in yeast-based xylitol production are focused on in this review, highlighting pretreatment methods, fermentation strategies, and product recovery.
BIOMASS CONVERSION AND BIOREFINERY
(2021)
Review
Agricultural Engineering
Juan Feng, Charin Techapun, Yuthana Phimolsiripol, Suphat Phongthai, Julaluk Khemacheewakul, Siraphat Taesuwan, Chatchadaporn Mahakuntha, Krisadaporn Porninta, Su Lwin Htike, Anbarasu Kumar, Rojarej Nunta, Sumeth Sommanee, Noppol Leksawasdi
Summary: This article introduces the sustainable approach of using biological conversion technology to treat agricultural waste. The abundant supply of cellulose, hemicellulose, and lignin provides great potential for waste conversion. Eco-friendly and economically feasible strategies can convert waste into useful products. The effectiveness, economic feasibility, technical procedures, and environmental impact of the technologies are comprehensively evaluated from an industrial scale viewpoint.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Vijay Kumar, Brian G. Fox, Taichi E. Takasuka
Summary: This study demonstrated the consolidated bioconversion of plant biomass to polyhydroxyalkanoate (PHA) by co-culturing two specialized bacteria, Streptomyces sp. SirexAA-E and Priestia megaterium. The co-culture produced poly(3-hydroxybutyrate) (PHB) using purified polysaccharides and various plant biomass as carbon sources. The optimized co-culture ratio of S. sp. SirexAA-E to P. megaterium produced 40 mg PHB/g Miscanthus using 0.5% biomass loading. This study provides a proof-of-concept for one-pot bioconversion of plant biomass into PHB without separate saccharification processes.
BIORESOURCE TECHNOLOGY
(2023)
Article
Environmental Sciences
Jazel Domenica Sosa-Martinez, Julio Montanez, Juan Carlos Contreras-Esquivel, Nagamani Balagurusamy, Suresh Kumar Gadi, Lourdes Morales-Oyervides
Summary: This study proposes a systematic approach to convert agro-industrial and food processing residues into valuable products via solid-state fermentation. The physicochemical properties of the residues were evaluated, and suitable strains were selected. The process conditions were optimized using statistical methods. The obtained enzyme extracts showed high efficiency in pectin extraction.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Multidisciplinary Sciences
Sitong Chen, Zhaoxian Xu, Boning Ding, Yuwei Zhang, Shuangmei Liu, Chenggu Cai, Muzi Li, Bruce E. Dale, Mingjie Jin
Summary: This study utilized phylogeny-guided big data mining, rational modification, and ancestral sequence reconstruction strategies to discover 13 new active xylose isomerases (XIs) for Saccharomyces cerevisiae, demonstrating the importance of the amino-terminal fragment for maintaining basic XI activity. These XIs were used to construct four efficient xylose-utilizing S. cerevisiae strains, and the strain S. cerevisiae CRD5HS achieved ethanol titers as high as 85.95 and 94.76 g/liter from pretreated corn stover and corn cob, respectively, without detoxifying or washing pretreated biomass. The genetic regulation mechanisms obtained from adaptive laboratory evolution provide practical references for mining other scarce and valuable enzymes.
Article
Agricultural Engineering
Vijay Kumar, Sanyukta Darnal, Subhash Kumar, Sanjay Kumar, Dharam Singh
Summary: A unique bacterium, Iodobacter sp. PCH 194, from the kettle lake at Sach Pass in western Indian Himalaya was found to co-produce PHA and violacein pigment. Through optimization, high-purity PHA and violacein pigment were obtained under specific culture conditions. Experimental validation showed that violacein has anticancer and antimicrobial activities.
BIORESOURCE TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Yao He, Hongxing Li, Liyuan Chen, Liyuan Zheng, Chunhui Ye, Jin Hou, Xiaoming Bao, Weifeng Liu, Yu Shen
Summary: The study focused on utilizing waste xylose mother liquor (WXML) and corncob residues to produce xylitol through engineered Saccharomyces cerevisiae strain. The simultaneous saccharification and fermentation (SSF) process showed promising results in terms of xylitol titer and productivity.
MICROBIAL BIOTECHNOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Raseena Naseema Rasheed, Asma Pourbakhtiar, Malihe Mehdizadeh Allaf, Maedeh Baharlooeian, Nahid Rafiei, Hossein Alishah Aratboni, Jose Ruben Morones-Ramirez, Flavia Vischi Winck
Summary: The growing human population has led to increased demand for raw materials and energy sources, resulting in harmful environmental impacts. To address this, utilizing microbial consortia or synthetic communities of microorganisms has emerged as a promising approach for sustainable bioproduct production and environmental remediation. Microalgae, in particular, show potential due to their ability to convert light energy and CO2 into valuable biomass. However, the development of microalgae co-cultivation techniques is still at an early stage and there are challenges in scaling up and commercializing these methods.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Farah Zahoor, Chayaphathra Sooklim, Pattanan Songdech, Orawan Duangpakdee, Nitnipa Soontorngun
Summary: Excessive use of antibiotics can lead to negative consequences, while diets rich in probiotics help maintain health. Yeast strains found in honey have the potential to act as probiotics and produce valuable metabolites.
Article
Chemistry, Applied
Le Wang, Yan Shen, Yuexia Zhang, Qixian Wei, Ying Liang, Hailong Tian, Dapeng Wu, Xueqing Yuan, Qipeng Yuan, Jinshui Wang
Summary: The novel treatment of carbon fiber with Fenton reagent significantly improved its surface properties and xylitol yield by introducing high-affinity iron ions to enhance the intracellular coenzyme cycle and reduce reactive oxygen species level. This method also increased immobilization efficiency and provided a biocompatible immobilized carrier for industrial production of xylitol.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Article
Polymer Science
Amir Sotoudeh, Goldis Darbemamieh, Vahabodin Goodarzi, Shahrokh Shojaei, Azadeh Asefnejad
Summary: The research introduced new biopolymers through chemical reactions between Xylitol, Dodecanedioic acid (DDA) and Lactic acid (LA), and analyzed their properties using various techniques. The presence of LA was found to have significant effects on the morphology and hydrophilic properties of the polymeric samples. Additionally, the inclusion of LA monomers and bio glass nanoparticles influenced the viscoelastic properties and degradation rate of the nanocomposite samples.
EUROPEAN POLYMER JOURNAL
(2021)
Review
Biochemistry & Molecular Biology
Yana Liu, Qin Wu, Xiangyun Wu, Samah Attia Algharib, Fayuan Gong, Junpeng Hu, Wanhe Luo, Meifang Zhou, Yuanhu Pan, YuanYuan Yan, Yulian Wang
Summary: Research on antibiotic substitutes such as beta-glucan and mannan from yeast cell wall has shown potential for prevention and treatment of animal diseases, reducing the development and spread of antibiotic-resistant pathogens. These compounds have various biological functions and can be enhanced through chemical modification or molecular weight reduction.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Sheetal Bandhu, Mahesh B. Khot, Tripti Sharma, Om P. Sharma, Diptarka Dasgupta, Swati Mohapatra, Saugata Hazra, Om P. Khatri, Debashish Ghosh
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2018)
Article
Agriculture, Multidisciplinary
Diptarka Dasgupta, Vivek Junghare, Abhilek K. Nautiyal, Arijit Jana, Saugata Hazra, Debashish Ghosh
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Omvir Singh, Tripti Sharma, Indrajit Ghosh, Diptarka Dasgupta, Bhanu Prasad Vempatapu, Saugata Hazra, Alexander L. Kustov, Bipul Sarkar, Debashish Ghosh
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2019)
Article
Energy & Fuels
Sheetal Bandhu, Neha Bansal, Diptarka Dasgupta, Vivek Junghare, Arushdeep Sidana, Gazal Kalyan, Saugata Hazra, Debashish Ghosh
Article
Agricultural Engineering
Neha Bansal, Diptarka Dasgupta, Saugata Hazra, Thallada Bhaskar, Anjan Ray, Debashish Ghosh
BIORESOURCE TECHNOLOGY
(2020)
Article
Agricultural Engineering
Ayan Banerjee, Tripti Sharma, Abhilek K. Nautiyal, Diptarka Dasgupta, Saugata Hazra, Thallada Bhaskar, Debashish Ghosh
BIORESOURCE TECHNOLOGY
(2020)
Article
Green & Sustainable Science & Technology
Diptarka Dasgupta, Arushdeep Sidana, Prasenjit Ghosh, Tripti Sharma, Jasvinder Singh, Asmita Prabhune, Snehal More, Thallada Bhaskar, Debashish Ghosh
Summary: The study demonstrates the process of xylitol production from corncob biomass with detailed energy and life cycle analysis. By utilizing microbial fermentation, D-xylose from biomass can be converted to xylitol with high selectivity, reducing energy consumption effectively.
JOURNAL OF CLEANER PRODUCTION
(2021)
Review
Chemistry, Medicinal
Vishal Ahuja, Amanpreet Singh, Debarati Paul, Diptarka Dasgupta, Petra Urajova, Sounak Ghosh, Roshani Singh, Gobardhan Sahoo, Daniela Ewe, Kumar Saurav
Summary: Edibles undergo physicochemical changes during preparation and storage, which can destroy their nutritive value and pose a threat to public health. Mass spectrometry is an ideal technique for detecting food toxins, but it faces challenges in routine food safety monitoring. However, continuous advancements in mass spectrometry technology and its integration with other techniques hold promising prospects for revolutionizing food safety monitoring.
CHEMICAL RESEARCH IN TOXICOLOGY
(2023)
Review
Biotechnology & Applied Microbiology
Megha Sailwal, Amar Jyoti Das, Rajesh K. Gazara, Diptarka Dasgupta, Thallada Bhaskar, Saugata Hazra, Debashish Ghosh
BIOTECHNOLOGY ADVANCES
(2020)
Article
Energy & Fuels
Diptarka Dasgupta, Akhilesh K. Kurmi, Dilip K. Adhikari, Debashish Ghosh
Article
Chemistry, Physical
Tripti Sharma, Diptarka Dasgupta, Jasvinder Singh, Thallada Bhaskar, Debashish Ghosh
SUSTAINABLE ENERGY & FUELS
(2020)
Article
Biotechnology & Applied Microbiology
Diptarka Dasgupta, Tripti Sharma, Aditya Bhatt, Sheetal Bandhu, Debashish Ghosh
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2017)
Article
Microbiology
Vera Analise Schommer, Mateus Torres Nazari, Flavia Melara, Julia Catiane Arenhart Braun, Alan Rempel, Lara Franco dos Santos, Valdecir Ferrari, Luciane Maria Colla, Aline Dettmer, Jeferson Steffanello Piccin
Summary: This review introduces the techniques and mechanisms of bacteria immobilization on biochar, as well as its applications in bioremediation and agriculture. The immobilization characteristics of biochar depend on pyrolysis methods, raw materials, and properties of biochar. Scanning electron microscope and colony forming unit analysis are commonly used to verify the immobilization efficiency. Applying biochar-immobilized bacteria can improve soil quality, plant growth, and crop yield.
MICROBIOLOGICAL RESEARCH
(2024)
Article
Microbiology
Manoj Kumar Solanki, Naveen Chandra Joshi, Prashant Kumar Singh, Sandeep Kumar Singh, Gustavo Santoyo, Lucas Carvalho Basilio de Azevedo, Ajay Kumar
Summary: The rhizosphere microbiome plays a crucial role in plant growth and health. Rhizosphere engineering can be used to modify the microbiome and improve plant productivity and resilience.
MICROBIOLOGICAL RESEARCH
(2024)
Article
Microbiology
Xin Cao, Xing-Wang Cheng, Yin-Ying Liu, Hong-Wei Dai, Ren-You Gan
Summary: Maintaining oral health is crucial for overall well-being. Imbalances in oral microorganisms can lead to various infectious diseases. Exploring alternatives for prevention and management of oral infections is important due to limitations of current treatments. Natural products offer potential as reliable, effective, and affordable therapeutic options for oral infectious diseases.
MICROBIOLOGICAL RESEARCH
(2024)
Article
Microbiology
Jose David Flores-Felix, Ana Carolina Goncalves, Sara Meirinho, Ana Raquel Nunes, Gilberto Alves, Cristina Garcia-Viguera, Diego A. Moreno, Luis R. Silva
Summary: The application of bacterial biofortifiers is increasing and has been shown to improve the nutritional characteristics of blueberries in Portugal.
MICROBIOLOGICAL RESEARCH
(2024)
Review
Microbiology
Asma Sani, Wan-Qi Qin, Jia-Yi Li, Yi-Fan Liu, Lei Zhou, Shi-Zhong Yang, Bo-Zhong Mu
Summary: This article summarizes the structural diversity of microbial lipopeptide biosurfactants and their applications as biocontrol agents in plants. Lipopeptides have low toxicity and wide range of applications, making them important in the pesticide industry.
MICROBIOLOGICAL RESEARCH
(2024)
Article
Microbiology
Xiao-Yu Sun, Jie Deng, Chenhui Zhang, Sin-Yee Fung, Kam-Leung Siu, Ying-Ying Cheng, Liumei Ye, Jiaoxia Qin, Ke Wang, Jiu-Xin Qu, Wenying Gao, Fuxiang Wang, Dong-Yan Jin, Liang Yang
Summary: In this study, a novel c-di-GMP binding protein SodA that regulates oxidative stress tolerance in S. maltophilia was identified. The enzyme activity of SodA was shown to be directly modulated by c-di-GMP through various in vivo and in vitro experiments.
MICROBIOLOGICAL RESEARCH
(2024)
