Copper binding and redox chemistry of the Aβ16 peptide and its variants: insights into determinants of copper-dependent reactivity

Resistance of Cu(Aβ4- 16) to Copper Capture by Metallothionein-3 Supports a Function for the Aβ4- 42 Peptide as a Synaptic CuII Scavenger

(2016) Nina E. Wezynfeld et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The CopC Family: Structural and Bioinformatic Insights into a Diverse Group of Periplasmic Copper Binding Proteins

(2016) Thomas J. Lawton et al.   BIOCHEMISTRY

Metal-catalyzed oxidation of Aβ and the resulting reorganization of Cu binding sites promote ROS production

(2016) Clémence Cheignon et al.   Metallomics

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding

(2015) Mariusz Mital et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Free Superoxide is an Intermediate in the Production of H2 O2 by Copper(I)-Aβ Peptide and O2

(2015) Karine Reybier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CopC Protein from Pseudomonas fluorescens SBW25 Features a Conserved Novel High-Affinity Cu(II) Binding Site

(2015) Chathuri J. K. Wijekoon et al.   INORGANIC CHEMISTRY

A set of robust fluorescent peptide probes for quantification of Cu(ii) binding affinities in the micromolar to femtomolar range

(2015) Tessa R. Young et al.   Metallomics

A rationally designed small molecule for identifying an in vivo link between metal–amyloid-β complexes and the pathogenesis of Alzheimer's disease

(2015) Michael W. Beck et al.   Chemical Science

Introduction of a Fluorescent Probe to Amyloid-β to Reveal Kinetic Insights into Its Interactions with Copper(II)

(2014) Thomas Branch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox Cycling of Copper–Amyloid β 1–16 Peptide Complexes Is Highly Dependent on the Coordination Mode

(2014) Lidia G. Trujano-Ortiz et al.   INORGANIC CHEMISTRY

3D Structures and Redox Potentials of Cu2+–Aβ(1–16) Complexes at Different pH: A Computational Study

(2014) Jorge Alí-Torres et al.   JOURNAL OF PHYSICAL CHEMISTRY B

An integrated study of the affinities of the Aβ16 peptide for Cu(i) and Cu(ii): implications for the catalytic production of reactive oxygen species

(2014) Tessa R. Young et al.   Metallomics

Zn impacts Cu coordination to amyloid-β, the Alzheimer's peptide, but not the ROS production and the associated cell toxicity

(2013) Bruno Alies et al.   CHEMICAL COMMUNICATIONS

Ligand-Field and Ligand-Binding Analysis of the Active Site of Copper-Bound Aβ Associated with Alzheimer’s Disease

(2013) Chandradeep Ghosh et al.   INORGANIC CHEMISTRY

Evaluation of quantitative probes for weaker Cu(i) binding sites completes a set of four capable of detecting Cu(i) affinities from nanomolar to attomolar

(2013) Zhiguang Xiao et al.   Metallomics

Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function

(2013) Su Ling Leong et al.   Metallomics

Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers

(2013) W. Mei Kok et al.   Chemical Science

Copper and Oxidative Stress in the Pathogenesis of Alzheimer’s Disease

(2012) Gözde Eskici et al.   BIOCHEMISTRY

Bioinorganic Chemistry of Alzheimer’s Disease

(2012) Kasper P. Kepp   CHEMICAL REVIEWS

Coordination of redox active metal ions to the amyloid precursor protein and to amyloid-β peptides involved in Alzheimer disease. Part 1: An overview

(2012) Christelle Hureau   COORDINATION CHEMISTRY REVIEWS

Coordination of redox active metal ions to the amyloid precursor protein and to amyloid-β peptides involved in Alzheimer disease. Part 2: Dependence of Cu(II) binding sites with Aβ sequences

(2012) Christelle Hureau et al.   COORDINATION CHEMISTRY REVIEWS

pH-Dependent Cu(II) Coordination to Amyloid-β Peptide: Impact of Sequence Alterations, Including the H6R and D7N Familial Mutations.

(2011) Bruno Alies et al.   INORGANIC CHEMISTRY

Unification of the Copper(I) Binding Affinities of the Metallo-chaperones Atx1, Atox1, and Related Proteins

(2011) Zhiguang Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modeling the Cu+Binding in the 1−16 Region of the Amyloid-β Peptide Involved in Alzheimer’s Disease

(2010) Sara Furlan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Electrochemical and homogeneous electron transfers to the Alzheimer amyloid-  copper complex follow a preorganization mechanism

(2010) V. Balland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deprotonation of the Asp1Ala2 Peptide Bond Induces Modification of the Dynamic Copper(II) Environment in the Amyloid-β Peptide near Physiological pH

(2009) Christelle Hureau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pulse EPR Spectroscopy Reveals the Coordination Sphere of Copper(II) Ions in the 1–16 Amyloid-β Peptide: A Key Role of the First Two N-Terminus Residues

(2009) Pierre Dorlet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Importance of dynamical processes in the coordination chemistry and redox conversion of copper amyloid-β complexes

(2009) Christelle Hureau et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Pleomorphic Copper Coordination by Alzheimer’s Disease Amyloid-β Peptide

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alanine-2 Carbonyl is an Oxygen Ligand in Cu2+Coordination of Alzheimer’s Disease Amyloid-β Peptide − Relevance to N-Terminally Truncated Forms

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Studies of Copper(I) Complexes of Amyloid-β Peptide Fragments: Formation of Two-Coordinate Bis(histidine) Complexes

(2008) Richard A. Himes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Metal Loading Ability of β-Amyloid N-Terminus: A Combined Potentiometric and Spectroscopic Study of Copper(II) Complexes with β-Amyloid(1−16), Its Short or Mutated Peptide Fragments, and Its Polyethylene Glycol (PEG)-ylated Analogue

(2008) Chiara A. Damante et al.   INORGANIC CHEMISTRY

The Amyloid-β Peptide of Alzheimer’s Disease Binds CuIin a Linear Bis-His Coordination Environment: Insight into a Possible Neuroprotective Mechanism for the Amyloid-β Peptide

(2008) Jason Shearer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY