Protective effect of tropisetron on high glucose induced apoptosis and oxidative stress in PC12 cells: roles of JNK, P38 MAPKs, and mitochondria pathway

High-Glucose-Derived Oxidative Stress-Dependent Heme Oxygenase-1 Expression from Astrocytes Contributes to the Neuronal Apoptosis

(2016) Chuen-Mao Yang et al.   MOLECULAR NEUROBIOLOGY

Tropisetron attenuated the anxiogenic effects of social isolation by modulating nitrergic system and mitochondrial function

(2015) Shayan Amiri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Tropisetron attenuates cisplatin-induced nephrotoxicity in mice

(2014) Mohammad Reza Zirak et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Depletion of end-binding protein 1 (EB1) promotes apoptosis of human non-small-cell lung cancer cells via reactive oxygen species and Bax-mediated mitochondrial dysfunction

(2013) Min-Jung Kim et al.   CANCER LETTERS

Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats

(2013) Reza Rahimian et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Tropisetron as a neuroprotective agent against glutamate-induced excitotoxicity and mechanisms of action

(2013) Michael M. Swartz et al.   NEUROPHARMACOLOGY

Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis

(2013) A. Aminian et al.   NEUROSCIENCE

The anti-inflammatory effects of the 5-HT3 receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes

(2012) Christian Stratz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hydroxyl Radical and Its Scavengers in Health and Disease

(2011) Boguslaw Lipinski   Oxidative Medicine and Cellular Longevity

Enhanced cytotoxicity and activation of ROS-dependent c-Jun NH2-terminal kinase and caspase-3 by low doses of tetrandrine-loaded nanoparticles in Lovo cells – A possible Trojan strategy against cancer

(2010) Xiaolin Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Granisetron ameliorates acetic acid-induced colitis in rats

(2010) Gohar Fakhfouri et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Multistep and multitask Bax activation

(2010) Lina Ghibelli et al.   MITOCHONDRION

Mechanism of diabetic neuropathy: Where are we now and where to go?

(2010) Soroku Yagihashi et al.   Journal of Diabetes Investigation

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Anti-inflammatory effects of 5-HT3receptor antagonist, tropisetron on experimental colitis in rats

(2009) K. Mousavizadeh et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Oxidative Stress, Diabetes, and Diabetic Complications

(2009) Wei Wei et al.   HEMOGLOBIN

A brief review ofin vitromodels of diabetic neuropathy

(2009) NamitaG Hattangady et al.   International Journal of Diabetes in Developing Countries

Diabetic neuropathy: Mechanisms to management

(2008) James L. Edwards et al.   PHARMACOLOGY & THERAPEUTICS