Plasminogen activator inhibitor links obesity and thrombotic cerebrovascular diseases: The roles of PAI-1 and obesity on stroke

Executive Summary: Heart Disease and Stroke Statistics—2016 Update

(2016) Dariush Mozaffarian et al.   CIRCULATION

Blood coagulation and metabolic profiles in middle-aged male and female ob/ob mice

(2015) Naoki Ohkura et al.   BLOOD COAGULATION & FIBRINOLYSIS

Visceral adipose tissue inflammation is associated with age-related brain changes and ischemic brain damage in aged mice

(2015) Jin A. Shin et al.   BRAIN BEHAVIOR AND IMMUNITY

Plasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic Testing

(2015) V. R. Placencio et al.   CANCER RESEARCH

Effects of Body Mass Index on the Lipid Profile and Biomarkers of Inflammation and a Fibrinolytic and Prothrombotic State

(2015) Esteban Orenes-Piñero et al.   Journal of Atherosclerosis and Thrombosis

Dynamic changes in plasma tissue plasminogen activator, plasminogen activator inhibitor-1 and beta-thromboglobulin content in ischemic stroke

(2015) Ping Zhuang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Association of visceral and total body fat with hypertension and prehypertension in a middle-aged Chinese population

(2015) Zengwu Wang et al.   JOURNAL OF HYPERTENSION

The Obesity Paradox in Stroke: Impact on Mortality and Short-term Readmission

(2015) Raquel Barba et al.   Journal of Stroke & Cerebrovascular Diseases

The Obesity Paradox in Stroke: Impact on Mortality and Short-term Readmission

(2015) Raquel Barba et al.   Journal of Stroke & Cerebrovascular Diseases

Visceral fat accumulation is associated with cerebral small vessel disease

(2014) K. Yamashiro et al.   EUROPEAN JOURNAL OF NEUROLOGY

Obesity-stroke paradox and initial neurological severity

(2014) Yerim Kim et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Oxidative Stress and Metabolic Pathologies: From an Adipocentric Point of View

(2014) Soazig Le Lay et al.   Oxidative Medicine and Cellular Longevity

Body Mass Index and Death by Stroke

(2014) Christian Dehlendorff et al.   JAMA Neurology

Inflammation, obesity, and thrombosis

(2013) F. Samad et al.   BLOOD

Three Decades of Research on Plasminogen Activator Inhibitor-1: A Multifaceted Serpin

(2013) Ann Gils et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Glycosylation influences the stability of human plasminogen activator inhibitor-1

(2012) Britt Van De Craen et al.   BLOOD COAGULATION & FIBRINOLYSIS

The obesity paradox: Methodological considerations based on epidemiological and clinical evidence—New insights

(2012) Christina-Maria Kastorini et al.   MATURITAS

Plasminogen Activator Inhibitor-1 and Thrombotic Cerebrovascular Diseases

(2012) Anna Tjärnlund-Wolf et al.   STROKE

Obesity

(2012) Walter N. Kernan et al.   STROKE

Tissue Plasminogen Activator Induced Delayed Edema in Experimental Porcine Intracranial Hemorrhage: Reduction with Plasminogen Activator Inhibitor-1 Administration

(2012) Naureen Keric et al.   Translational Stroke Research

Body Mass Index, Initial Neurological Severity and Long-Term Mortality in Ischemic Stroke

(2011) Wi-Sun Ryu et al.   CEREBROVASCULAR DISEASES

Childhood obesity: evidence of an association between plasminogen activator inhibitor-1 levels and visceral adiposity

(2011) Rafael M. Mantovani et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Obesity and Recurrent Vascular Risk After a Recent Ischemic Stroke

(2011) Bruce Ovbiagele et al.   STROKE

REVIEW: Plasminogen Activator Inhibitor-1 (PAI-1): A Key Factor Linking Fibrinolysis and Age-Related Subclinical and Clinical Conditions

(2010) Matteo Cesari et al.   Cardiovascular Therapeutics

Visceral fat decreased by long-term interdisciplinary lifestyle therapy correlated positively with interleukin-6 and tumor necrosis factor–α and negatively with adiponectin levels in obese adolescents

(2010) Fábio Santos Lira et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Bezafibrate Induces Plasminogen Activator Inhibitor-1 Gene Expression in a CLOCK-Dependent Circadian Manner

(2010) K. Oishi et al.   MOLECULAR PHARMACOLOGY

Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: Essential role of astrocyte-derived plasminogen activator inhibitor-1

(2010) Ji Woon Kim et al.   NEUROCHEMISTRY INTERNATIONAL

Therapeutic Administration of Plasminogen Activator Inhibitor-1 Prevents Hypoxic-Ischemic Brain Injury in Newborns

(2009) D. Yang et al.   JOURNAL OF NEUROSCIENCE

The Impact of Body Mass Index on Mortality After Stroke

(2009) Amytis Towfighi et al.   STROKE

Transcriptional regulation of plasminogen activator inhibitor-1 in vascular endothelial cells induced by oxidized very low density lipoproteins

(2008) Ruozhi Zhao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Body Mass Index and Poststroke Mortality

(2008) Tom Skyhøj Olsen et al.   NEUROEPIDEMIOLOGY

The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes

(2007) Helmut Laumen et al.   ATHEROSCLEROSIS