Review
Biochemistry & Molecular Biology
Nadia Lampiasi
Summary: Mast cells and macrophages are innate immune cells that play important roles in maintaining tissue homeostasis and responding to inflammatory conditions. Their crosstalk is essential for optimal coordination of their functions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Public, Environmental & Occupational Health
Jessica L. Puranda, Danilo F. da Silva, Chris M. Edwards, Taniya S. Nagpal, Sara S. Souza, Kevin Semeniuk, Kristi B. Adamo
Summary: This study investigates reproductive health factors in female Canadian Armed Forces (CAF) members and their association with musculoskeletal injuries. The results reveal that irregular menstrual cycles or absence of periods increase the likelihood of experiencing musculoskeletal injuries, while endometriosis is associated with higher rates of acute injuries.
JOURNAL OF WOMENS HEALTH
(2023)
Review
Biochemistry & Molecular Biology
Jinyu Chen, Yiwei Fang, Ying Xu, Haotong Sun
Summary: This review examines the role of N6-methyladenosine (m6A) in reproductive processes and discusses its changes in female reproductive system diseases. It highlights the potential of m6A and its protein machineries as markers and targets for diagnosing and treating female reproductive dysfunction.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Environmental Sciences
Emily L. Silva, Douglas I. Walker, Zoe Coates Fuentes, Brismar Pinto-Pacheco, Christine N. Metz, Peter K. Gregersen, Shruthi Mahalingaiah
Summary: This study conducted a preliminary untargeted metabolomic analysis of menstrual blood, and identified various environmental chemicals, including suspected reproductive toxicants. The study also found that the endogenous metabolites detected in menstrual blood samples provided good coverage of the human blood metabolome. Therefore, menstrual blood samples have potential applications in exposome research.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Obstetrics & Gynecology
Shuhui Li, Hongxin Liu, Di Li, Fei Chen
Summary: The COVID-19 pandemic has imposed a heavy burden on medical systems and has also affected the female reproductive system through various mechanisms. Evidence suggests that SARS-CoV-2 does not directly infect the female reproductive system, but inflammation and nervous system damage caused by the virus may indirectly influence sex hormone concentrations. Menstrual disorders in infected women may be caused by various factors. COVID-19 vaccination does not significantly affect ovarian follicle quality and in vitro fertilization parameters, and most side effects of vaccination can recover within a short period of time.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Endocrinology & Metabolism
Eija K. Laakkonen, Jari E. Karppinen, Satu Lehti, Earric Lee, Emilia Pesonen, Hanna-Kaarina Juppi, Urho M. Kujala, Eero A. Haapala, Pauliina Aukee, Jari A. Laukkanen, Johanna K. Ihalainen
Summary: This study investigated the association of sex hormones with arterial stiffness in women aged 19-58 years. While age seemed to have a significant impact on arterial stiffness across a wide age range, the hormonal status showed differential associations with arterial stiffness in age-group focused analyses. Further research is needed to clarify potential hormone-mediated mechanisms affecting arterial elasticity.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Health Care Sciences & Services
Tali Azenkot, Eleanor Bimla Schwarz
Summary: Anticoagulation therapy for women of reproductive age poses unique challenges, including issues related to menstrual management, prevention of hemorrhagic ovarian cysts, and contraception. The subdermal implant may be the preferred contraceptive option, and progestin-only formulations are generally preferred. Tranexamic acid and endometrial ablation may be useful in managing menorrhagia and dysmenorrhea.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Pediatrics
Xiao Ma, Dongyan Cao, Peng Peng, Yu Xiao, Jiaxin Yang, Huifang Huang, Ying Zhang, Mei Yu, Jinhui Wang, Huimei Zhou, Ninghai Cheng, Tao Wang, Keng Shen
Summary: This study summarized the clinical features, treatment modalities, outcomes, and prognosis of extragonadal yolk sac tumors (YSTs) of the female genital tract. The results showed that BEP chemotherapy can be preferred for vaginal and uterine YSTs, and vaginohysteroscopy and pediatric rhinoscopy can be used for diagnosis and evaluation of treatment efficacy in pediatric patients.
FRONTIERS IN PEDIATRICS
(2022)
Article
Zoology
M. Rughetti, M. Ferloni
Summary: In female mammals, the cost of reproduction can affect future survival or reproduction. This study found that the number of newborns produced in a breeding season can impact the body mass of female hares at the end of the reproductive season. Heavier female hares are able to bear the cost of reproduction, produce more offspring, and maintain a larger body size.
JOURNAL OF ZOOLOGY
(2023)
Review
Immunology
Kazuhide Takada, Vyacheslav G. Melnikov, Ryoki Kobayashi, Shihoko Komine-Aizawa, Noriko M. Tsuji, Satoshi Hayakawa
Summary: This review discusses the bidirectional communication between the female reproductive tract (FRT) and remote/versatile organs in the body. The framework of the FRT-organ axes, including various axes such as the vagina-gut axis and uterus-brain axis, is comprehensively discussed. Each axis is not only involved in gynecological diseases, but also diseases occurring outside the FRT. The investigation of the FRT-organ axes provides a multi-centric approach to understand the homeostatic mechanism of women's bodies and may lead to new therapeutic approaches for women's health.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Immunology
Rinki Minakshi, Safikur Rahman, Archana Ayaggari, Durgashree Dutta, Abhishek Shankar
Summary: The intricacies of signaling routes involved in the menstrual cycle can be affected by internal and external stimuli, and stress can disrupt this process for women. Understanding the immune panorama in the female reproductive tract is crucial in understanding the issue of menstrual disturbance. The presence of microbiota in both the lower and upper reproductive tract and inflammation as an underlying phenomenon are important factors to consider. Sex hormones and cortisol play a significant role in the immune response, and treatment regimens should take into account the different phases of the ovarian cycle.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Ecology
Stephen P. De Lisle, Daniel I. Bolnick
Summary: Parasites can affect host fitness through direct and indirect effects, with an inducible immune defense in a fish-tapeworm system causing reduced parasite burden but also lower foraging success and reproductive fitness. Despite shared costs and benefits of immune response, males and females in the study populations experience unequal impacts due to differing infection risks.
Article
Biology
Astrid Rox, Sophie Waasdorp, Elisabeth H. M. Sterck, Jan A. M. Langermans, Annet L. Louwerse
Summary: Female rhesus macaques in multigenerational breeding groups have higher reproductive success, including higher birth rates and offspring survival, compared to females in peer groups. Multigenerational breeding groups provide a win-win situation, optimizing both female reproductive success and animal welfare.
Article
Obstetrics & Gynecology
Stephanie W. Edmonds, Michelle A. Mengeling, Craig H. Syrop, James C. Torner, Anne G. Sadler
Summary: The study found that over half of female veterans have experienced lifetime sexual assault, and these women have differences in family planning behaviors compared to those who have not experienced such assaults, highlighting the need for special support in family planning and reproductive health care.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Marine & Freshwater Biology
Emily I. Palmer, Emma L. Betty, Sinead Murphy, Matthew R. Perrott, Adam N. H. Smith, Karen A. Stockin
Summary: In this study, the reproductive biology of common dolphins along the New Zealand coastline was assessed. The age and length at sexual maturity were estimated, and it was found that the number of corpora in mature individuals increased with age. Ovarian asymmetry was also observed, with higher rates of ovulation in the left ovary. The study showed that conception and calving occurred year-round, with a weak seasonal increase. The findings provide important baseline data for monitoring population parameters and highlight the potential adaptations of the species to local conditions.