Article
Endocrinology & Metabolism
Daqi Zhang, Mingyu Yang, Xin Zhang, Cheng Wang, Kunlin Li, Hongbo Wang, Hao Chi, Chengqiu Sui, Gianlorenzo Dionigi, Hui Sun
Summary: This study presents a rare case series of synchronous occurrence of medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) in the same thyroid gland. The synchronous MTC/PTC were classified into 4 subtypes and the clinical and pathological aspects as well as the results were presented.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Jae Hoon Moon, Chang Hwan Ryu, Sun Wook Cho, June Young Choi, Eun-Jae Chung, Jeong Hun Hah, Yul Hwangbo, Woo-Jin Jeong, Yuh-Seog Jung, Ji-Hoon Kim, Min Joo Kim, Su-Jin Kim, Yeo Koon Kim, Chang Yoon Lee, Eun Kyung Lee, Ji Ye Lee, Kyu Eun Lee, You Jin Lee, Yumi Lee, Hyeong Won Yu, Do Joon Park, Junsun Ryu, Young Joo Park
Summary: The study found that for patients with low-risk PTMC, choosing active surveillance may have a positive impact on quality of life over a 2-year period.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Jinlong Huo, Yaxuan Xu, Jie Yu, Youming Guo, Xiaochi Hu, Dong Ou, Rui Qu, Lijin Zhao
Summary: This study evaluated the feasibility, safety, and oncologic outcomes of endoscopic thyroidectomy via the areolar approach (ETAA) compared to conventional open thyroidectomy (COT) for stage T1 papillary thyroid carcinoma (PTC). The results showed that ETAA was a safe and feasible surgical method with comparable oncologic completeness to COT. ETAA had longer operative time and higher postoperative drainage and C-reactive protein levels, but provided better cosmetic satisfaction and quality of life for patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Min Ding, Gao-Song Wu, Jian-Hua Gu, Dong-Jie Shen, Rui Zhou, Ying Liu, Rong-Li Xie, Shu-Rong Wang, Hong-Cheng Wang, Jian Fei
Summary: This study investigated the efficacy and safety of microwave ablation (MWA) for papillary thyroid carcinoma (PTC) by examining postoperative pathology results. The findings suggest that MWA is a feasible and effective treatment option for primary unifocal low-risk micro-PTC.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Oncology
Yu Lan, Li Cao, Qing Song, Zhuang Jin, Jing Xiao, Lin Yan, Yukun Luo, Mingbo Zhang
Summary: The study aimed to compare the HRQoL of PTMC patients undergoing TT and LT. Results showed a significant negative linear association between LT and TT groups in terms of RP, RE, SF, PCS, and MCS. THYCA-QOL scores indicated that the TT group had higher levels of complaints regarding scars compared to the LT group, while there was no significant difference in FoP-Q-SF scores between the two groups.
Article
Radiology, Nuclear Medicine & Medical Imaging
Mo-han Guo, Jian-ping Dou, Lin Zheng, Fang-yi Liu, Jie Yu, Zhi-gang Cheng, Xiao-ling Yu, Ying Che, Shu-rong Wang, Zhi-bin Cong, Nan Bai, Cun Liu, Ying Hao, Ming-an Yu, Zhi-feng Xu, Zhi-yu Han, Ping Liang, Lei Chen
Summary: This study compared the real-world efficacy and safety of microwave ablation (MWA) and surgery for treating T1bN0M0 PTC. The results showed no significant difference between MWA and surgery in terms of local tumor progression, new thyroid cancer, lymph node metastasis, and distant metastasis. MWA may be an optional choice for low-risk T1bN0M0 PTC patients, but concerns about lymph node metastasis need further study.
EUROPEAN RADIOLOGY
(2023)
Review
Otorhinolaryngology
Alvaro Sanabria, Pilar Pinillos, Renan B. Lira, Jatin P. Shah, Ralph P. Tufano, Mark E. Zafereo, Iain J. Nixon, Gregory W. Randolph, Ricard Simo, Vincent Vander Poorten, Alessandra Rinaldo, Jesus E. Medina, Avi Khafif, Peter Angelos, Antti A. Makitie, Ashok R. Shaha, Juan P. Rodrigo, Dana M. Hartl, Luiz P. Kowalski, Alfio Ferlito
Summary: The study reviewed literature on the indications for management selection for low-risk thyroid carcinomas, finding significant heterogeneity in inclusion and exclusion criteria. The most commonly reported inclusion criteria were nodule diameter and histopathological confirmation of tumor type, while lymph node metastasis and extra-thyroidal extension were common exclusions. Alternative therapeutic approaches in low-risk carcinomas can be considered cautiously, with open thyroidectomy remaining the standard treatment.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Surgery
Chang Myeon Song, Hyang Sook Bang, Hyung Gu Kim, Hae Jin Park, Kyung Tae
Summary: This study compared health-related quality of life after transoral robotic thyroidectomy and conventional thyroidectomy, finding higher scores for neck appearance and improved anxiety in the robotic group after surgery. However, total scores for health-related quality of life did not differ between the two groups postoperatively.
Article
Surgery
Wenjie Chen, Genpeng Li, Ke Jiang, Jinen Song, Runzi Du, Hui Yang, Juxiang Gou, Zhihui Li, Jingqiang Zhu, Jianyong Lei
Summary: This study demonstrates that a single dose of dexamethasone is effective and safe for preventing PONV in patients with PTC.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lin Zheng, Jian-ping Dou, Fang-yi Liu, Jie Yu, Zhi-gang Cheng, Xiao-ling Yu, Hui Wang, Cun Liu, Ming-an Yu, Zhi-bin Cong, Shu-rong Wang, Ying Che, Zhi-feng Xu, Ying Hao, Nan Bai, Xue Wang, Ying Liu, Ying Zhou, Jing Shi, Zhao-hu Fu, Hong-yan Zhan, Zhi-yu Han, Ping Liang
Summary: This study compared the safety and efficacy of microwave ablation (MWA) and surgery for treating papillary thyroid carcinomas (PTC) with sonographically detected minimal extrathyroid extension (mETE). The results showed that MWA was comparable to surgery in terms of treatment safety and efficacy in the short term, with the advantages of shorter operation time, less blood loss, and lower costs. The surgery group had higher scores for scar problems and anxiety.
EUROPEAN RADIOLOGY
(2023)
Article
Endocrinology & Metabolism
Natalia Chaves, Jordan M. Broekhuis, Scott C. Fligor, Reagan A. Collins, Anna M. Modest, Sumedh Kaul, Benjamin C. James
Summary: This study investigated the impact of delays in surgery on survival in patients with papillary thyroid cancer (PTC). The results showed that increasing time to surgery was associated with decreased overall survival and disease-specific survival. Specifically, delays in surgery increased mortality risk in patients with localized disease.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Otorhinolaryngology
Krupa R. Patel, Bo Wang, Amr Abdelhamid H. Ahmed, Okenwa C. Okose, Honghzhi Ma, Ian J. Behr, Anthony Y. Cheung, Yoshiyuki Saito, Dipti Kamani, Amanda Silver Karcioglu, Whitney Liddy, Hiroshi Takami, MaryBeth Cunnane, Gregory W. Randolph
Summary: This study aimed to investigate the surgical and biochemical outcomes of nerve-monitored reoperation or revision surgery for recurrent thyroid cancers. It was found that reoperation surgery may help achieve biochemical remission regardless of age or the number of prior surgeries.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Endocrinology & Metabolism
Jiahao Wang, Jun Wang, Jinxing Quan, Juxiang Liu, Limin Tian, Changhong Dong
Summary: The expression level of NDRG3 can be used for the differential diagnosis between papillary thyroid carcinoma and benign thyroid nodules, and also serves as a molecular marker for the diagnosis of papillary thyroid carcinoma.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Francesca Galuppini, Simona Censi, Isabella Merante Boschin, Matteo Fassan, Marta Sbaraglia, Nicola Valeri, Jens Claus Hahne, Loris Bertazza, Giada Munari, Marco Galasso, Luciano Cascione, Susi Barollo, Massimo Rugge, Federica Vianello, Angelo Paolo Dei Tos, Caterina Mian, Gianmaria Pennelli
Summary: This study analyzed the miRNA expression profiles of different histological variants and mutations in papillary thyroid carcinoma (PTC) samples and found that miRNA signatures were associated with specific histotypes and BRAF mutations.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Oncology
Chao Zeng, Jiali Long, Chunmiao Deng, Linying Xie, Hongmei Ma, Yimin Guo, Shuguang Liu, Min Deng
Summary: This study analyzed the mutation spectrum and mutation signature of papillary thyroid carcinoma (PTC) with Hashimoto's thyroiditis (TH) and identified several significantly mutated genes, including ANK3, which may serve as a diagnostic marker for PTC. The study also found that overexpression of ANK3 suppressed PTC cell invasion, migration, and growth. The findings suggest that ANK3 plays an anti-oncogenic role in PTC development.
FRONTIERS IN ONCOLOGY
(2022)