Novel synthesis of isoindoline/isoindoline-1,3-dione derivatives under solventless conditions and evaluation with the human D2 receptor

Computational protein–ligand docking and virtual drug screening with the AutoDock suite

(2016) Stefano Forli et al.   Nature Protocols

Disruption of motor behavior and injury to the CNS induced by 3-thienylboronic acid in mice

(2016) E.D. Farfán-García et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Dual effects of l-DOPA on nigral dopaminergic neurons

(2013) Ezia Guatteo et al.   EXPERIMENTAL NEUROLOGY

Determination of key receptor–ligand interactions of dopaminergic arylpiperazines and the dopamine D2 receptor homology model

(2013) Vladimir Sukalovic et al.   JOURNAL OF MOLECULAR MODELING

CYP2D6 phenotypes and Parkinson's disease risk: A meta-analysis

(2013) Yu Lu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Synthesis, docking and acetylcholinesterase inhibitory assessment of 2-(2-(4-Benzylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives with potential anti-Alzheimer effects

(2013) Ahmad Mohammadi-Farani et al.   DARU-Journal of Pharmaceutical Sciences

Comparison of the Binding and Functional Properties of Two Structurally Different D2 Dopamine Receptor Subtype Selective Compounds

(2012) Robert R. Luedtke et al.   ACS Chemical Neuroscience

Synthesis of an Isoindoline-Annulated, Tricyclic Sultam Library via Microwave-Assisted, Continuous-Flow Organic Synthesis (MACOS)

(2012) Paul Hanson et al.   SYNTHESIS-STUTTGART

Synthesis of a Unique Isoindoline/Tetrahydroisoquinoline-based Tricyclic Sultam Library Utilizing a Heck-aza-Michael Strategy

(2012) Qin Zang et al.   ACS Combinatorial Science

Theoretical study of 3-D molecular similarity and ligand binding modes of orthologous human and rat D2 dopamine receptors

(2011) Marvin A. Soriano-Ursúa et al.   COMPUTERS IN BIOLOGY AND MEDICINE

The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients

(2011) Amandeep Mann et al.   NEUROBIOLOGY OF AGING

Synthesis and pharmacological evaluation of aminoacetylenic isoindoline-1,3-dione derivatives as anti-inflammatory agents

(2011) Jinan A. Al-Qaisi et al.   Arabian Journal of Chemistry

Novel Organotin(IV)-Schiff Base Complexes: Synthesis, Characterization, Antimicrobial Activity, and DNA Interaction Studies

(2010) K. Shiva Prasad et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS

Molecular modeling study of isoindolines as L-type Ca2+ channel blockers by docking calculations

(2010) Teresa Mancilla-Percino et al.   JOURNAL OF MOLECULAR MODELING

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

Diketoacid-genre HIV-1 integrase inhibitors containing enantiomeric arylamide functionality

(2009) Xue Zhi Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme

(2009) Bo Wang et al.   DRUG METABOLISM REVIEWS

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Evaluation of D2 and D3 dopamine receptor selective compounds on l-dopa-dependent abnormal involuntary movements in rats

(2009) Rakesh Kumar et al.   NEUROPHARMACOLOGY

Animal models of Parkinson’s disease progression

(2008) Gloria E. Meredith et al.   ACTA NEUROPATHOLOGICA

Modeling PD pathogenesis in mice: Advantages of a chronic MPTP protocol

(2008) Gloria E. Meredith et al.   PARKINSONISM & RELATED DISORDERS