Article
Biochemistry & Molecular Biology
Azza A. A. Attia, Jehan M. M. Sorour, Neama A. A. Mohamed, Tagreed T. T. Mansour, Rasha A. A. Al-Eisa, Nahla S. S. El-Shenawy
Summary: This study aimed to investigate the protective role of vitamin E in improving cardiotoxicity induced by cyclophosphamide in rats. The results showed that vitamin E could attenuate the elevation of cardiac markers, increase in lipid profiles, reduction in antioxidant enzyme activities, and increase in lipid peroxidation. In addition, vitamin E was found to improve the histopathological alterations caused by cyclophosphamide.
Article
Environmental Sciences
Megha Murali, T. Shivanandappa
Summary: Endosulfan exposure causes high levels of oxidative stress in the liver and brain, leading to reduced antioxidant enzyme activity and increased ROS and lipid peroxidation. The brain is more susceptible to oxidative stress than the liver, likely due to its lower antioxidant defenses and higher oxygen consumption.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Plant Sciences
Ragia M. Mazrou, Sabry Hassan, Mei Yang, Fahmy A. S. Hassan
Summary: Exogenous melatonin (MT) treatment was found to extend the vase life of cut roses by maintaining relative water content and reducing stomatal aperture. In addition, MT treatment increased phenol content, enzyme activities, and radical scavenging capacity, while reducing H2O2 production and lipid peroxidation. This overall contributed to membrane stability maintenance and preservation of postharvest quality in cut flowers.
Article
Food Science & Technology
Chunfeng Wang, Chenxu Cui, Ning Li, Xuefeng Sun, Liuding Wen, Enguang Gao, Fangyu Wang
Summary: This study found that wheat germ peptides can effectively mitigate the cellular damage induced by alpha-gliadin peptide, providing a new perspective for the prevention and treatment of celiac disease.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Multidisciplinary Sciences
Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-Ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, Andre Santos Dias Mourao, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt, Marcus Conrad
Summary: A study identifies the anti-ferroptotic function of vitamin K and reveals FSP1 as the enzyme mediating warfarin-resistant vitamin K reduction, highlighting the importance of FSP1 in protecting cells against lipid peroxidation and ferroptosis.
Article
Environmental Sciences
Farid Abdelrazek, Dawlat A. Salama, Afaf Alharthi, Saeed A. Asiri, Dina M. Khodeer, Moath M. Qarmush, Maysa A. Mobasher, Mervat Ibrahim
Summary: This study investigated the antioxidant protective effect of glycine betaine (GB) against lead-induced renal and hepatic injury. The results showed that GB significantly reduced renal and liver damage caused by lead by activating antioxidant enzymes and preventing lead-induced oxidative damage.
Article
Biochemistry & Molecular Biology
Hanna Lesiewska, Alina Wozniak, Pawel Reisner, Krzysztof Czosnyka, Joanna Stachura, Grazyna Malukiewicz
Summary: Oxidative stress and depletion of antioxidant defenses may contribute to cataract incidence in patients under 60 years. This study measured antioxidant enzyme activity, vitamin concentrations, and oxidative stress markers in cataract patients and controls. The results showed lower activity of antioxidant enzymes and lower concentrations of vitamins A and E in cataract patients. Additionally, higher levels of lipid peroxidation and protein oxidation were observed, indicating increased oxidative stress in cataract patients. Supplementation with antioxidants could be beneficial for this group of patients.
Article
Biochemistry & Molecular Biology
Priscila Ortega, Hector Aguilar Vitorino, Shadaesha Green, Flavia P. Zanotto, J. Sook Chung, Renata G. Moreira
Summary: The study showed that in crabs from highly contaminated areas, cadmium bioaccumulation, oxidative stress, and hormone levels were higher compared to those from lightly contaminated areas, while the transcripts of crustacean hyperglycemic hormone and molt-inhibiting hormone decreased.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Fisheries
Hongjian Lu, Zhengxi Wang, Yuwei Ding, Xue Feng, Chunxian Zhao, Linghan Chen, Weizhi Yao, Dan Xi, Mei Fu
Summary: In this study, it was found that injection of Calcein (CAL) could induce a strong oxidative stress response in juvenile silver carp. The severity of oxidative stress was correlated with the injection dose and time after injection. Higher CAL doses could lead to greater toxicity in the fish. When using CAL for fluorescent labeling, the injection dose should be restricted to 25 mg/kg or less and the injected fish should be reared for at least 16 days.
Article
Biochemistry & Molecular Biology
David Soriano-Castell, Antonio Currais, Pamela Maher
Summary: Ferroptosis is a form of regulated cell death dependent on iron and lipid peroxidation. Various inhibitors have been tested to distinguish ferroptosis from other forms of cell death.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Environmental Sciences
Javaid Akhter Bhat, Masroor Ahmad Bhat, Dyaaaldin Abdalmegeed, Deyue Yu, Jian Chen, Andrzej Bajguz, Ajaz Ahmad, Parvaiz Ahmad
Summary: The study demonstrated that the combined application of Fe2O3-NPs and CA had a better alleviating effect on As toxicity in soybean. Fe2O3-NPs and CA significantly reversed As-induced growth inhibition and oxidative stress responses, partially reducing the production of MDA and H2O2.
ENVIRONMENTAL POLLUTION
(2022)
Article
Chemistry, Applied
Rouhollah Karimi, Khaled Gavili-Kilaneh, Ali Khadivi
Summary: The foliar spray of methyl jasmonate (MJ), especially at 100 μM, was found to alleviate the negative effects of salinity stress in grapes by improving physiological parameters, reducing ion leakage, increasing photosynthetic pigments and proline content, and enhancing antioxidant enzyme activity.
Article
Environmental Sciences
Abdul Qader, Kanwal Rehman, Muhammad Sajid Hamid Akash
Summary: This study investigated the impairment of lipid metabolism induced by lead (Pb) and its amelioration through plant-based therapeutic interventions. Pb-induced hepatotoxicity disrupted the normal levels of antioxidant enzymes, leading to lipid peroxidation. Additionally, Pb toxicity altered the regulation of hormones involved in the synthesis of HMG-CoA reductase, resulting in abnormal levels of serum cholesterol and other lipid molecules. The administration of resveratrol effectively treated Pb toxicity. Overall, this study demonstrated the therapeutic effect of resveratrol in improving Pb-induced lipid metabolism impairment by using vitamin C as a standard intervention.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Khian Giap Lim, Rajavel Varatharajan, Arunachalam Muthuraman
Summary: This study investigated the beneficial effects of beta-carotene on diabetes-associated vascular dementia and its antioxidative actions. Beta-carotene treatment improved cognitive function and reduced oxidative stress markers in rats with diabetic vascular dementia.
Article
Environmental Sciences
Yanqiang Li, Jun Wang, Zhongkang Yang, Guangde Li, Zhongwen Zhang, Dexin Zhang, Hui Sun
Summary: This study investigated the effects of MTBE on oxidative stress and DNA damage in earthworms. The results showed that MTBE treatment increased the production of ROS, activated defense enzymes, and caused DNA damage in earthworms. This study contributes to a better understanding of the impact of MTBE on soil invertebrate animals.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
