Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells

Combination treatment with flavonoid morin and telomerase inhibitor MST-312 reduces cancer stem cell traits by targeting STAT3 and telomerase

(2016) Seyung S. Chung et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells

(2016) Suman Suman et al.   Oncotarget

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

(2016) Harini Nivarthi et al.   Oncotarget

Pretreatment serum interleukin-1β, interleukin-6, and tumor necrosis factor-αlevels predict the progression of colorectal cancer

(2016) Pei-Hung Chang et al.   Cancer Medicine

Hepatitis C Virus–Associated Cancer

(2015) Ming V. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ

(2014) Karen Heyninck et al.   BIOCHEMICAL PHARMACOLOGY

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Signal Transducer and Activator of Transcription 3·Nuclear Factor κB (Stat3·NFκB) Complex Is Necessary for the Expression of Fascin in Metastatic Breast Cancer Cells in Response to Interleukin (IL)-6 and Tumor Necrosis Factor (TNF)-α

(2014) Marylynn Snyder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutive Activation of STAT3 Signaling Regulates hTERT and Promotes Stem Cell-Like Traits in Human Breast Cancer Cells

(2013) Seyung S. Chung et al.   PLoS One

NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer

(2013) Yihui Fan et al.   Protein & Cell

Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland

(2013) Foteini Hassiotou et al.   Frontiers in Oncology

Synergistic cytotoxic action of cisplatin and withaferin A on ovarian cancer cell lines

(2012) Sham S. Kakar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer-Initiating Cells

(2011) L. Lin et al.   CANCER RESEARCH

Intestinal Inflammation and Cancer

(2011) Thomas A. Ullman et al.   GASTROENTEROLOGY

Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

(2011) Jose T. Thaiparambil et al.   INTERNATIONAL JOURNAL OF CANCER

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Oct4-Induced Pluripotency in Adult Neural Stem Cells

(2009) Jeong Beom Kim et al.   CELL

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

(2009) Mohammad Mirjalili et al.   MOLECULES