The Role of PDGFs and PDGFRs in Colorectal Cancer

Platelet-derived growth factor receptor/platelet-derived growth factor (PDGFR/PDGF) system is a prognostic and treatment response biomarker with multifarious therapeutic targets in cancers

(2016) Kwaku Appiah-Kubi et al.   TUMOR BIOLOGY

Targeting Angiogenesis in Cancer Therapy: Moving Beyond Vascular Endothelial Growth Factor

(2015) Y. Zhao et al.   ONCOLOGIST

PDGFRB Promotes Liver Metastasis Formation of Mesenchymal-Like Colorectal Tumor Cells

(2015) Ernst J.A. Steller et al.   NEOPLASIA

Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive

(2014) A O'Toole et al.   BRITISH JOURNAL OF CANCER

PDGF receptor signaling networks in normal and cancer cells

(2014) Jean-Baptiste Demoulin et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Vascular Endothelial Growth Factor Signaling in Hypoxia and Inflammation

(2014) S. Ramakrishnan et al.   Journal of Neuroimmune Pharmacology

Antiangiogenesis therapy: an update after the first decade

(2014) Sandro De Falco   KOREAN JOURNAL OF INTERNAL MEDICINE

Study of the cellular mechanism of Sunitinib mediated inactivation of activated hepatic stellate cells and its implications in angiogenesis

(2013) Syamantak Majumder et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Proangiogenic tumor proteins as potential predictive or prognostic biomarkers for bevacizumab therapy in metastatic colorectal cancer

(2013) Maressa A. Bruhn et al.   INTERNATIONAL JOURNAL OF CANCER

Effect of the tyrosine kinase inhibitor nilotinib in patients with hypereosinophilic syndrome/chronic eosinophilic leukemia: analysis of the phase 2, open-label, single-arm A2101 study

(2013) Andreas Hochhaus et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Multifarious functions of PDGFs and PDGFRs in tumor growth and metastasis

(2013) Yihai Cao   TRENDS IN MOLECULAR MEDICINE

VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients

(2012) Jon E. Peterson et al.   ANGIOGENESIS

Platelet-derived growth factors and their receptors: Structural and functional perspectives

(2012) Po-Han Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome

(2012) Purificacion Estevez-Garcia et al.   BMC CANCER

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Rapid Angiogenesis Onset after Discontinuation of Sunitinib Treatment of Renal Cell Carcinoma Patients

(2012) A. W. Griffioen et al.   CLINICAL CANCER RESEARCH

Mutation in the platelet-derived growth factor receptor alpha inhibits adeno-associated virus type 5 transduction

(2012) Ingo H. Pilz et al.   VIROLOGY

Physical–chemical principles underlying RTK activation, and their implications for human disease

(2011) Lijuan He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Platelet-Derived Growth Factor (Subtype BB) Is Elevated in Patients with Colorectal Carcinoma

(2011) Avraham Belizon et al.   DISEASES OF THE COLON & RECTUM

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

(2011) Yuan Xue et al.   NATURE MEDICINE

Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch

(2010) W. Ding et al.   BLOOD

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor β is associated with lymphatic metastasis in human gastric carcinoma

(2010) Michiyo Kodama et al.   CANCER SCIENCE

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

(2010) T. Ozawa et al.   GENES & DEVELOPMENT

KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia

(2010) S Medves et al.   LEUKEMIA

(Pre-)Clinical Pharmacology and Activity of Pazopanib, a Novel Multikinase Angiogenesis Inhibitor

(2010) P. Hamberg et al.   ONCOLOGIST

Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis

(2009) Konstantin Gaengel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ligand-Dependent Platelet-Derived Growth Factor Receptor (PDGFR)-  Activation Sensitizes Rare Lung Cancer and Sarcoma Cells to PDGFR Kinase Inhibitors

(2009) U. McDermott et al.   CANCER RESEARCH

Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts

(2008) C. Anderberg et al.   CANCER RESEARCH

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

mRNA Expression of Platelet-Derived Growth Factor Receptor-β and C-KIT: Correlation With Pathologic Response to Cetuximab-Based Chemoradiotherapy in Patients With Rectal Cancer

(2008) Philipp Erben et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS