Article
Chemistry, Physical
Lorena Kostelac, Luca Pezzato, Alessio Giorgio Settimi, Mattia Franceschi, Claudio Gennari, Katya Brunelli, Chiara Rampazzo, Manuele Dabala
Summary: In this study, bioactive coatings were produced on grade 2 titanium alloy using plasma electrolytic oxidation (PEO) process. The effects of KOH addition to electrolyte and working in direct or pulsed current mode were investigated. The coatings exhibited improved corrosion resistance and cell adhesion compared to the untreated sample.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Physical
Sezgin Cengiz, Aytekin Uzunoglu, Sabrina M. Huang, Lia Stanciu, Mehmet Tarakci, Yucel Gencer
Summary: The study demonstrates that the morphology and chemical composition of surface coatings synthesized on Zirconium substrates can affect bioactivity. The relationship between the surface morphology, chemical composition, and bioproperties was investigated, showing that the size of the pores and chemical composition of the coating surface are closely related to the development of hydroxyapatite structure and cell growth.
SURFACES AND INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Yevheniia Husak, Joanna Michalska, Oleksandr Oleshko, Viktoriia Korniienko, Karlis Grundsteins, Bohdan Dryhval, Sahin Altundal, Oleg Mishchenko, Roman Viter, Maksym Pogorielov, Wojciech Simka
Summary: The research aimed to develop a stable oxidative coating on Mg alloy using plasma electrolytic oxidation (PEO) in silicate-based solutions. The addition of Ca(OH)2 in the electrolyte was crucial for the formation of biocompatible oxide coatings with enhanced surface properties.
Review
Chemistry, Multidisciplinary
Soumya Sikdar, Pramod Menezes, Raven Maccione, Timo Jacob, Pradeep L. Menezes
Summary: Plasma electrolytic oxidation (PEO) is a novel surface treatment process used to produce thick, dense metal oxide coatings on light metals to improve their wear and corrosion resistance. The PEO process is widely employed in mechanical, petrochemical, and biomedical industries due to its superior characteristics. Recently, PEO process has also been utilized to produce nanocomposite coatings, showing promising developments in this field.
Article
Materials Science, Ceramics
Maryam Molaei, Arash Fattah-alhosseini, Meisam Nouri, Alireza Nourian
Summary: By optimizing five process variables, two groups of PEO coatings were studied, with results indicating that the first group exhibited better biocompatibility properties.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Coatings & Films
Fajar Al Afghani, Anawati Anawati
Summary: The study suggests that using a mixed electrolyte containing phosphate, silicate, and hydroxide can reduce power consumption during plasma electrolytic oxidation (PEO) of zircaloy-4. The resulting coating consisted of SiO2 and ZrO2 phases, with the coating formed at 70 mA/cm(2) exhibiting the highest wear resistance and corrosion resistance.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Anderson Wagner Alves de Menezes, Ivan Alves de Souza, Thercio Henrique de Carvalho Costa, Tharsia Cristiany de Carvalho Costa, Romulo Ribeiro Magalhaes de Sousa, Rubens Maribondo Nascimento, Michelle de Medeiros Aires, Michelle Cequeira Feitor
Summary: The tissue-prosthesis relationship is crucial for the success of an implant, and efforts have been made to improve the affinity between the implant and the human body. This study successfully produced a hydroxyapatite coating on metallic surfaces using plasma electrolytic oxidation, and investigated the effects of treatment time, current behavior, and polarity on the coating formation.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Materials Science, Multidisciplinary
Fatemeh Salahshouri, Ehsan Saebnoori, Sina Borghei, Majid Mossahebi-Mohammadi, Hamid Reza Bakhsheshi-Rad, Filippo Berto
Summary: This study investigated the effect of applied voltage on the microstructure, bioactivity, and corrosion rate of plasma electrolytic oxidation coatings on gamma-TiAl alloy. The results showed that higher surface pore sizes of the coatings provided more suitable sites for the formation of hydroxyapatite. Furthermore, the PEO coatings applied with 500 V displayed better cell attachment performance.
Review
Chemistry, Physical
Arash Fattah-alhosseini, Razieh Chaharmahali, Mohsen K. Keshavarz, Kazem Babaei
Summary: Zirconium and its alloys are widely used in orthopedic, dental, and hard tissue implants due to their high biocompatibility and corrosion resistance, but surface modification is essential for durable medical applications. Plasma electrolytic oxidation (PEO) can produce a uniform, thick, hard, and sticky oxide coating on the surface of zirconium, allowing for controlled coating properties to enhance bioactive and biocompatibility behavior.
SURFACES AND INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Sergiy Kyrylenko, Maciej Sowa, Alicja Kazek-Kesik, Agnieszka Stolarczyk, Marcin Pisarek, Yevheniia Husak, Viktoriia Korniienko, Volodymyr Deineka, Roman Moskalenko, Izabela Matula, Joanna Michalska, Agata Jakobik-Kolon, Oleg Mishchenko, Maksym Pogorielov, Wojciech Simka
Summary: Dental implants made from titanium and its alloys are commonly used due to their inertness and biocompatibility. However, to improve their success rate, it is necessary to enhance the integration with bone and gum tissues and prevent bacterial infections. Various surface modification techniques, including plasma electrolytic oxidation (PEO), have been explored. In this study, the use of nitrilotriacetic acid (NTA) as a complexing agent in the PEO process was found to improve the corrosion resistance of titanium implants and reduce bacterial colonization.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Oktay Yigit, Niyazi Ozdemir, Burak Dikici, Mosab Kaseem
Summary: Nano-hydroxyapatite-matrix coatings containing graphene nanosheets were successfully coated on Ti6Al7Nb alloys through plasma electrolytic oxidation treatment, improving the coating's hardness and corrosion resistance.
Article
Materials Science, Coatings & Films
Zilin Chen, Xu Liu, Zhe Cheng, Xiaodong Tan, Yunjie Xiang, Jing Li, Yongping Zhang, Zhisong Lu, En-Tang Kang, Liqun Xu, Xi Rao
Summary: A ZnO/Zn(OH)(2) hybrid coating was fabricated on pure Zn surface through plasma electrolytic oxidation (PEO) to investigate the effect of PEO treatment on the degradation behavior of Zn and Zn-based materials. The degradation effects were studied through immersion tests in simulated body fluid (SBF) and Hank's solution. The results showed that PEO treatment accelerates the degradation of Zn and the corrosion products mainly consist of Zn(OH)(2), ZnO, Zn-3(PO4)(2), and Ca-P matters. PEO-treated Zn exhibited good in vitro biocompatibility and enhanced antibacterial properties, making it promising for orthopedic implants.
SURFACE & COATINGS TECHNOLOGY
(2023)
Article
Chemistry, Physical
Vladlens Grebnevs, Katarzyna Lesniak-Ziolkowska, Marta Wala, Mateusz Dulski, Sahin Altundal, Aleksandrs Dutovs, Liga Avotina, Donats Erts, Roman Viter, Arturs Viksna, Wojciech Simka
Summary: One way to improve the characteristics of oxide coatings prepared by plasma electrolytic oxidation (PEO) method is to vary the properties of solid particles. In this study, the effect of particle crystallinity on the physicochemical properties and bioactivity of coatings on Ti and Ti6Al4V substrates was investigated. It was found that the crystallinity of particles had a specific influence on surface morphology and the pattern of particle incorporation, which ultimately affected the coating's bioactivity. Variation of particle crystallinity was proposed as a potential tool for adjusting PEO coating properties.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Vignesh Raj Sivaperumal, Rajkumar Mani, Veerababu Polisetti, Kanakaraj Aruchamy, Taehwan Oh
Summary: Calcium phosphate-based ceramic material is a potential candidate for dental restorations and bone replacements, but its limited thermal processing ability and weak mechanical strength have hindered its application in hard tissue engineering. In this study, zirconia was used to reinforce hydroxyapatite, resulting in improved biocompatibility and mechanical stability.
APPLIED SCIENCES-BASEL
(2022)
Article
Materials Science, Coatings & Films
Jinlong Pan, Yanwei Wen, Lili Wang, Zhiyong Wu, Hui Dong, Zuoyan Ye
Summary: Plasma electrolytic oxidation (PEO) can be used to create black ceramic films on aluminum alloy by incorporating transition metal anions into the electrolyte. The research focused on modifying the bandgap of alumina, revealing that doping transition metals into alumina narrowed the bandgap, resulting in the absorption of all visible light and the appearance of black color.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Materials Science, Ceramics
Salih Durdu, Gizem Cihan, Emine Yalcin, Atilgan Altinkok
Summary: The study successfully created TiO2 nanotube array surfaces at different voltages and analyzed their morphology, composition, properties, and mechanical performance. It was found that the roughness and thickness of the nanotube structures increased with higher voltage values.
CERAMICS INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Shun-Yi Jian, Salim Levent Aktug, Hsuan-Ti Huang, Cheng-Jung Ho, Sung-Yen Lin, Chung-Hwan Chen, Min-Wen Wang, Chun-Chieh Tseng
Summary: Micro arc oxidation (MAO) was used to modify the surface characteristics of AZ31 Mg alloy for implant applications, resulting in improved biocompatibility, corrosion resistance, and the formation of a calcium phosphate (Ca-P) containing thin film. After in-vivo implantation, the coating showed enhanced proliferation activity, better corrosion resistance, and lower roughness compared to mere MAO coatings on AZ31 alloy. This study demonstrates the potential feasibility of using MAO coatings for orthopedic implants in clinical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Coatings & Films
Salih Durdu, Muharrem Sancak, Emine Yalcin, Metin Usta, Eyup Akagunduz, Atilgan Altinkok
Summary: Highly ordered TiO2 nanotube arrays were prepared on Ti6Al4V substrate through anodic oxidation technique, showing good surface roughness and thickness distribution, as well as higher hydrophobicity compared to uncoated titanium surface. The hardness and elastic modulus of TiO2 nanotube surfaces were close to bone structure, with good adhesion properties between similar to 2.2 N and similar to 4.6 N.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Chun-Wei Chen, Salim Levent Aktug, Chin-Jou Chang, Yueh-Lien Lee, Ming-Der Ger, Shun-Yi Jian
Summary: This study characterizes and determines the corrosion resistance of Mn-Ce conversion coated LZ91 magnesium alloy. It is found that using acid pickling as a pretreatment and applying a conversion coating can effectively improve the corrosion resistance of the magnesium alloy.
Article
Engineering, Electrical & Electronic
Fatih Unal, Mustafa Sukru Kurt, Salih Durdu
Summary: In this study, the fabrication and electrical characterization of Si/TiO2 heterojunctions were investigated, and the heterojunctions exhibited rectifying properties and sensitive photodiode behavior to light. The research provides insights into the performance of heterojunctions under different light intensities.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2022)
Article
Materials Science, Multidisciplinary
Chia-Yu Lee, Jeou-Long Lee, Shun-Yi Jian, Chi-An Chen, Salim Levent Aktug, Ming-Der Ger
Summary: This study investigates the addition of fluoride to the electroless nickel-phosphorus plating solution to improve the corrosion resistance of MAO-coated AZ31B magnesium alloy. Fluoride reacts with Ni2+ ions and the MAO coating to form interphases, which enhance bonding and corrosion resistance. The presence of fluoride in the plating solution results in a more corrosion-resistant coating. The composition, structure, and morphology of the coatings are characterized using various analytical techniques, and their corrosion resistance is evaluated using different tests.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Materials Science, Multidisciplinary
Salih Durdu, Ahmet Arslanturk, Salim Levent Aktug, Kemal Korkmaz, Sitki Aktas, Fatih Unal, Emine Yalcin, Kultigin Cavusoglu
Summary: The aim of this study was to develop antimicrobial and bioactive surfaces on commercial pure titanium for dental and orthopedic applications. The researchers successfully produced silver, copper, and zinc-based TiO2 coatings on titanium surfaces, which showed improved antibacterial properties and bioactivity.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Salih Durdu, Sergen Tosun, Emine Yalcin, Kultigin Cavusoglu, Atilgan Altinkok, Hasan Sagcan, Ilknur Yurtsever, Metin Usta
Summary: By coating CuNPs on nanotube surfaces, the corrosion resistance of Ti6Al4V alloy can be enhanced, and the biological properties such as antibacterial activities, cell viability, and ALP activity can be improved, while reducing protein adsorption and hemolytic activity. This has significant implications for orthopedic and dental implant applications.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Multidisciplinary Sciences
Salih Durdu, Emine Yalcin, Atilgan Altinkok, Kultigin Cavusoglu
Summary: One of the main reasons for the premature failure of Ti-based implants is infections. Metal- and metal oxide-based nanoparticles have high potential for controlling infections. In this study, randomly distributed AgNPs-deposited onto well-ordered TiO2 nanotube surfaces were fabricated on titanium using anodic oxidation and electrochemical deposition processes. The AgNPs-deposited nanotube surfaces exhibited hydrophilic behaviors, which were beneficial for bone tissue growth. They also showed great corrosion resistance and improved electrochemical corrosion resistance compared to bare Gr2 surface. Additionally, the AgNPs-deposited nanotube surfaces exhibited antibacterial activity and high stability for long-term usage of implant applications.
SCIENTIFIC REPORTS
(2023)
Article
Materials Science, Multidisciplinary
Salim Levent Aktug, Dogan Acar, Omer Necati Cora, Salih Durdu
Summary: In this study, aerospace-grade Ti6Al4V alloy was coated using electro spark deposition (ESD), micro-arc oxidation (MAO), and combined ESD + MAO coating methods to enhance mechanical properties and wear resistance. The phase structure, surface-cross sectional morphologies, elemental distribution, surface-cross sectional mechanical and wear properties were investigated and compared with bare Ti6Al4V. The results showed that the coatings had improved hardness and wear resistance due to their crystalline and dense structure, with MAO and ESD + MAO coatings containing rutile-TiO2 and γ-Al2O3 phases.
KOVOVE MATERIALY-METALLIC MATERIALS
(2023)
Article
Multidisciplinary Sciences
Salih Durdu, Gizem Cihan, Emine Yalcin, Kultigin Cavusoglu, Atilgan Altinkok, Hasan Sagcan, Ilknur Yurtsever, Metin Usta
Summary: To improve the properties of commercial pure titanium for implant applications, Zn-deposited nanotube surfaces were fabricated using anodic oxidation and physical vapor deposition methods. The Zn-deposited surfaces showed hydrophobic character and higher corrosion current density compared to bare titanium surfaces. These surfaces exhibited improved cell viability, ALP activity, and antibacterial properties, with decreased hemolytic activity and protein adsorption. The Zn-deposited nanotube surfaces produced on commercial pure titanium have potential for orthopedic and dental implant applications.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Tuba Yildiz, Salih Durdu, Kadriye Ozcan, Metin Usta
Summary: In this study, AgNPs-doped surfaces were produced on zirconium by micro arc oxidation and electrochemical deposition. These surfaces exhibited hydrophilic behaviors and improved bioactivity compared to bare Zr substrate under simulated body fluid conditions. Importantly, the AgNPs-doped surfaces showed antimicrobial activity against E. coli and S. aureus.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Salim Levent Aktug, Salih Durdu, Selin Kalkan, Kultigin Cavusoglu, Metin Usta
Summary: The Ca-based porous and rough bioceramic surfaces were coated onto zirconium by micro-arc oxidation, and then covered with an antimicrobial chitosan layer to create a composite material suitable for implant applications. The presence of chitosan significantly enhanced the in vitro bioactivity and reduced microbial adhesion for Staphylococcus aureus and Escherichia coli.
SCIENTIFIC REPORTS
(2021)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)