Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 71, Issue -, Pages 345-350Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.msec.2016.10.027
Keywords
Forcespinning (TM); SERS; Bacteria detection; S. aureus; P. aeruginosa and S. Typhimurium
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Funding
- National Science Centre [UMO-2015/17/B/ST4/04128]
- EC 7.FP fund: the Research Potential (Coordination and Support Actions) [FP7-REGPOT-CT-2011-285949-NOBLESSE]
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One of potential applications of nano- and microscale polymer fibers is SERS-active platforms for the detection of biological compounds and microorganisms. This paper demonstrates the polymer mat obtained with Forcespinning (TM) technique used to detect the bacteria from blood plasma. Forcespinning (TM) is a new method of manufacturing of polymer fibers which can be applied to variety of polymer materials, e.g. polyethylene, nylon, PA6 and others. The method is based on the centrifugal force to draw fiber from molten polymer, which allows tuning the diameter of the fiber from tens of nanometers up to micrometers. Wide range of diameters makes the forcespun polymer mat an excellent material to filter bacteria from fluids (e.g. blood plasma, water). Covering the mat with Au:Ag alloy turns it into a SERS platform able to immobilize, detect, and identify bacteria. We provide proof-of-concept, showing detection of S. aureus, P. aeruginosa, and S. Typhimurium from blood plasma. (C) 2016 Elsevier B.V. All rights reserved.
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