Article
Chemistry, Analytical
Madalina Simona Baltatu, Andrei Victor Sandu, Marcin Nabialek, Petrica Vizureanu, Gabriela Ciobanu
Summary: Research efforts to improve metallic biomaterials have led to the development of TiMoZrTa (TMZT) alloys with coatings of hydroxyapatite using a biomimetic method, showcasing good biocompatibility and mechanical properties, with potential for dental and orthopedic implant applications.
Article
Engineering, Biomedical
Limin Ma, Xiaolan Wang, Ye Zhou, Xiongfa Ji, Shi Cheng, Dong Bian, Lei Fan, Lei Zhou, Chengyun Ning, Yu Zhang
Summary: Titanium-based scaffolds are commonly used for bone defect treatment, but conventional implants lack adequate biomechanical properties for bone integration. A novel Ti-6Al-4V alloy/GelMA hybrid scaffold (GMPT) was developed with dual bionic features for bone defect repair, showing improved osteogenic and angiogenic capabilities. The concentration of GelMA significantly influenced gene expression related to bone formation and angiogenesis pathways in the GMPT scaffold, demonstrating promise for large bone defect restoration.
BIOACTIVE MATERIALS
(2021)
Article
Engineering, Biomedical
Tatiani Ayako Goto Donato, Karolyne dos Santos Jorge Sousa, Pedro Akira Bazaglia Kuroda, Carlos Roberto Grandini
Summary: This study aimed to produce Ti-15Nb alloy with a low elastic modulus and verify its biocompatibility. The results showed that the heat treatments can modify the structure and mechanical properties of the alloy. Rapid cooling promoted the formation of the beta phase, while slow cooling promoted the formation of the alpha phase. Additionally, the Ti-15Nb alloy did not show cytotoxic effects on osteogenic cells, and there were no variations in cell quantity.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Hongwei Zhang, Wentao Qin, Cheng Man, Hongzhi Cui, Decheng Kong, Zhongyu Cui, Xin Wang, Chaofang Dong
Summary: This study investigates the influence of heat treatments on the microstructure and corrosion behavior of PBF-LB Ti6Al4V. The results show that different evolution processes occur at different temperatures, and the galvanic effect between alpha and beta phases affects the corrosion resistance of PBF-LB Ti6Al4V.
Article
Engineering, Mechanical
Jacek Grabarczyk, Justyna Gaj, Bartosz Pazik, Witold Kaczorowski, Bartlomiej Januszewicz
Summary: A combined surface modification method involving the deposition of carbon coating on thermally treated titanium alloy was proposed in this study. The oxidized and then DLC-coated samples showed the most outstanding results, enhancing low surface friction and coating durability, while maintaining high corrosion resistance.
TRIBOLOGY INTERNATIONAL
(2021)
Article
Materials Science, Multidisciplinary
W. F. Liu, X. W. Gao, L. Wang, J. H. Yao, Q. B. Fan, J. J. Yuan, S. Li
Summary: A clad plate of high strength Ti386 and high plasticity TC4 was manufactured by hot rolling and solution-aging treatment. The interfacial bonding strength and tensile properties of the clad plate were improved by increasing the rolling reduction and carrying out solution-aging treatment.
Article
Materials Science, Multidisciplinary
A. B. Batibay, F. Erci, H. Kotan, Z. Karavelioglu, R. Cakir Koc, I. Oral, A. Evcin
Summary: In this research, TixNbxSn (x = 5, 10, 15, 20 wt%) alloys were synthesized and their potential as biomaterials was investigated. The results showed the presence of α-Ti, β-Ti, and TiC phases in the microstructure after high-temperature sintering. The hardness and elastic modulus of the alloys varied depending on their compositions, with Ti15Nb15Sn alloy having the closest elastic modulus to bone. The TiNbSn alloys exhibited antibacterial properties against S. aureus and were not cytotoxic to healthy cells, with noticeable enhancement in cell proliferation and viability.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Materials Science, Coatings & Films
Yu Zheng, Peng Xu, Long Li, Qibin Liu, Shanzhu Guo
Summary: In this study, TixNb alloy coatings with excellent mechanical properties and biocompatibility were fabricated by laser cladding. The biocompatibility, mechanical properties, and corrosion resistance of the coatings were discussed. The results showed that the coatings had high microhardness, wear resistance, and corrosion resistance. Cell experiments demonstrated that the coatings had better biocompatibility than Ti6Al4V.
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A
(2023)
Article
Chemistry, Physical
Agnieszka Ossowska, Jean -Marc Olive, Andrzej Zielinski, Andrzej Wojtowicz
Summary: The research focused on the development and characterization of innovative thin hybrid oxide coatings obtained through thermal and electrochemical oxidation processes. Different surface modifications were investigated to improve the mechanical, chemical, and biological properties of Ti-13Nb-13Zr alloy. The study showed that the double titanium oxide coatings produced had high surface roughness, corrosion resistance, hydrophilicity, slight antibacterial properties, and were not cytotoxic, which have significant implications for tissue-implant integration.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Seiji Yamaguchi, Phuc Thi Minh Le, Seine A. Shintani, Hiroaki Takadama, Morihiro Ito, Sara Ferraris, Silvia Spriano
Summary: The study developed a new method to incorporate iodine into titanium and its alloys, enhancing their antibacterial properties and demonstrating strong antibacterial activity against various bacteria. The treated metals showed long-term stability in antibacterial activity and cytocompatibility, making them potentially useful for orthopedic and dental implants.
Article
Chemistry, Multidisciplinary
Madalina Simona Baltatu, Cristiana Chiriac-Moruzzi, Petrica Vizureanu, Laszlo Toth, Janos Novak
Summary: In this study, the effects of aging on the structure, microhardness, and indentation test of titanium alloys were investigated. The heat treatment process greatly influenced the microhardness and modulus of elasticity of the alloys. The results suggest that improving the heat treatment process can enhance the properties of titanium alloys.
APPLIED SCIENCES-BASEL
(2022)
Article
Metallurgy & Metallurgical Engineering
Changzheng Li, Yunchang Xin, Guangjie Huang, Qing Liu
Summary: A quantitative study was conducted on the microstructure and orientation of titanium hydrides during electrochemical hydrogen charging and subsequent annealing treatment. The results showed that delta-hydride is the main form, and annealing treatment resulted in a new orientation relationship between hydrides and the matrix.
ACTA METALLURGICA SINICA-ENGLISH LETTERS
(2022)
Review
Materials Science, Multidisciplinary
Joanna Sypniewska, Marek Szkodo
Summary: This paper analyzes the effects of laser modification on titanium and its alloys, including surface roughness, wettability, corrosion resistance, hardness, and wear resistance. A thorough review of the literature provides a basis for further research on the relationship between laser beam effects and surface characteristics.
Article
Nanoscience & Nanotechnology
Felicity F. Worsnop, Susannah L. M. Lea, Jan Ilavsky, David Rugg, David Dye
Summary: Increasing attention is being paid to alpha(2) Ti-3(Al,Sn) precipitation in jet engine titanium due to its impact on slip band formation, localization, and fatigue performance. However, observing the early stages of alpha(2) precipitation has been challenging using traditional methods. This study used small angle X-ray scattering to reexamine the phase boundary in Ti-Al and Ti-Sn alloys with O content, and found that the phase boundaries in the literature were approximately correct. The findings suggest that Al may be a more suitable solid solution strengthener than Sn for ambient temperature applications, but lower Al-eq limits should be considered for future alloy design.
SCRIPTA MATERIALIA
(2023)
Article
Nanoscience & Nanotechnology
Zhiyi Zou, Marco Simonelli, Juliano Katrib, Georgios Dimitrakis, Richard Hague
Summary: Tailored heat treatments can enhance the mechanical properties of additive manufactured Ti-6Al-4V by achieving desirable microstructures. Rapid heat treatments are found to significantly refine the prior-? grains and alter the morphology of the resulting microstructure without sacrificing ductility.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2021)
Article
Engineering, Biomedical
Lais Morandini Rodrigues, Elis A. Lima Zutin, Elisa M. Sartori, Fabio A. P. Rizzante, Daniela B. S. Mendonca, Paul H. Krebsbach, Karl J. Jepsen, Lyndon F. Cooper, Luana M. R. Vasconcellos, Gustavo Mendonca
Summary: The study found that nanoscale surface implants promoted more bone formation associated with higher levels of Osterix gene expression. The surface characteristics of these implants can directly influence bone formation by adherent cells.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2022)
Review
Biochemistry & Molecular Biology
Noala Vicensoto Moreira Milhan, William Chiappim, Aline da Graca Sampaio, Mariana Raquel da Cruz Vegian, Rodrigo Savio Pessoa, Cristiane Yumi Koga-Ito
Summary: The use of plasma-activated water (PAW) in dentistry shows potential advantages for treating oral diseases, compared to direct application of non-thermal atmospheric pressure plasmas (NTAPPs).
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Geane Garcia Chales, Beatriz Siqueira Tihameri, Noala Vicensoto Moreira Milhan, Cristiane Yumi Koga-Ito, Maria Lucia Pereira Antunes, Adriano Goncalves dos Reis
Summary: This study investigated the application of Moringa oleifera seed-derived coagulants in the treatment of synthetic turbid water. The results showed that these coagulants were effective in removing turbidity, with saline extraction obtaining the best results. The coagulants also had an impact on pH and electrical conductivity, as well as the presence of residual organic matter. Defatted seeds were found to reduce water cytotoxicity. However, caution should be exercised when using high dosages of saline extractions due to their effects on electrical conductivity and cytotoxicity.
Article
Materials Science, Multidisciplinary
Patricia Capellato, Filipe Bueno Vilela, Andres Henrique Palomo Fontenele, Gilbert Silva, Kerolene Barboza da Silva, Joao Pedro Aquiles Carobolante, Edwin Gilberto Medina Bejarano, Mirian de Lourdes Noronha Motta Melo, Ana Paula Rosifini Alves Claro, Daniela Sachs
Summary: The growth of the elderly population necessitates the use of suitable biomaterials for better surgical and implant procedures and faster patient healing. A novel ternary beta-phase alloy of Ti10Mo8Nb was studied and found to have suitable properties for biomedical applications, especially in orthopedics and dentistry, with the potential to reduce stress shielding.
Article
Materials Science, Multidisciplinary
Larissa Mayra Silva Ribeiro, Luziane Aparecida Costa da Rosa Simoes, Melina Espanhol-Soares, Vinicius Carvalho Teles, Tainara Aparecida Nunes Ribeiro, Patricia Capellato, Lucas Victor Benjamim Vasconcelos Fre, Bruna Horta Bastos Kuffner, Stephen Edward Saddow, Daniela Sachs, Ana Paula Rosifini Alves Claro, Rossano Gimenes
Summary: This study aims to develop a method for coating an experimental Ti-30Ta alloy with a copolymer P(VDF-TrFE)/BaTiO3, and the results show that the coated Ti-30Ta alloy exhibits high thermal stability and piezoelectric properties. The surface treatment and polishing have significant effects on the adhesion of the coating.
Article
Biochemistry & Molecular Biology
Aline da Graca Sampaio, William Chiappim, Noala Vicensoto Moreira Milhan, Benedito Botan Neto, Rodrigo Pessoa, Cristiane Yumi Koga-Ito
Summary: This study evaluated the antimicrobial effects of different plasma-activated liquids on Escherichia coli and their cytotoxicity on mammalian cells. The results showed that plasma-activated deionized water, plasma-activated distilled water, and plasma-activated tap water exhibited the best antimicrobial effects at different exposure times. Additionally, all plasma-activated liquids demonstrated low toxicity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Joao Pedro Aquiles Carobolante, Adelvam Pereira Junior, Celso Bortolini Junior, Kerolene Barboza da Silva, Roberta Maia Sabino, Ketul C. Popat, Ana Paula Rosifini Alves Claro
Summary: The study focuses on the development and characterization of a new Ti10Mo8Nb6Zr beta alloy for bone tissue repair. The alloy processing involved melting, heat treatment, and forging. The results showed that the alloy exhibited good biocompatibility, superior cell viability, and low Young's modulus, making it a promising candidate for biomedical applications.
Article
Engineering, Biomedical
Patricia dos Santos Calderon, Fernanda Regina Godoy Rocha, Xinyi Xia, Samira Esteves Afonso Camargo, Ana Luisa de Barros Pascoal, Chan-Wen Chiu, Fan Ren, Steve Ghivizzani, Josephine F. Esquivel-Upshaw
Summary: This study evaluated the influence of titanium nanotube diameter and the effect of silicon carbide coating on pre-osteoblast proliferation and mineralization on titanium nanostructured surfaces. The results showed that the titanium nanotube diameter did not affect cell viability or mineralization, while the silicon carbide coating contributed to increased osteoblast mineralization.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
Article
Materials Science, Coatings & Films
Rebeca F. B. de O. Correia, Aline G. Sampaio, Noala V. M. Milhan, Ariel Capote, Holger Gerdes, Kristina Lachmann, Vladimir J. Trava-Airoldi, Cristiane Yumi Koga-Ito, Ralf Bandorf
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A
(2023)
Review
Biochemistry & Molecular Biology
Ana Bessa Muniz, Mariana Raquel da Cruz Vegian, Lady Daiane Pereira Leite, Diego Morais da Silva, Noala Vicensoto Moreira Milhan, Konstantin Georgiev Kostov, Cristiane Yumi Koga-Ito
Summary: The potential of non-thermal atmospheric pressure plasma (NTPP) application in Endodontics was evaluated through a literature review. NTPP showed a disinfection property against important endodontic microorganisms, mainly Enterococcus faecalis and Candida albicans. The association of NTPP and conventional antimicrobial solutions was shown to be more effective than both treatments separately, with potential implications for clinical practice. However, more studies are still required to standardize the parameters and explore the use of plasma-activated liquids in endodontic treatments.
Article
Engineering, Biomedical
Juliani Caroline Ribeiro de Araujo, Leonardo Alvares Sobral Silva, Vinicius Almeida de Barros Lima, Tiago Moreira Bastos Campos, Paulo Noronha Lisboa Filho, Roberta Okamoto, Luana Marotta Reis de Vasconcellos
Summary: With increasing life expectancy, the prevalence of osteoporosis has risen, leading to a search for strategies to regenerate bone tissue. The sonochemical technique was used to functionalize bioglass, resulting in modified surface characteristics. In vitro tests showed favorable cell adhesion and differentiation, with no cytotoxicity observed. Animals treated with teriparatide demonstrated new bone formation, indicating positive effects on bone tissue. Further studies are required to investigate the long-term effects of the interaction between bioglass and teriparatide.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Materials Science, Textiles
Lilian de Siqueira, Veronica Ribeiro dos Santos, Juliani Caroline Ribeiro de Araujo, Hugo Gutemberg Patino de Oliveira Filho, Luana Marotta Reis de Vasconcellos, Eliandra de Sousa Triches, Alexandre Luiz Souto Borges
Summary: This study developed a novel method to improve the properties of biomaterials by electrospinning poly (lactic acid) (PLA)/polycaprolactone (PCL) fibers and electrospraying bioactive particles from an amorphous multicomponent silica-calcium-phosphorus system (AMS). In vitro and in vivo evaluations were conducted using male rats, and the results showed promising outcomes for bone regeneration.
FIBERS AND POLYMERS
(2023)
Article
Biology
Sarah O. M. Avelino, Rafael M. Neves, Leonardo A. Sobral-Silva, Rubens N. Tango, Claudio A. Federico, Mariana R. C. Vegian, Luis Augusto de Almeida-Silva, Estela Kaminagakura, Jose Benedito O. Amorim, Luana M. R. Vasconcellos
Summary: This study assessed the impact of radiotherapy on soft tissue in surgical wounds in rats. The results showed that radiotherapy had effects on the surrounding soft tissues, regardless of the duration.
Article
Nanoscience & Nanotechnology
Mirian M. Machado-Paula, Marcus A. F. Corat, Luana M. R. de Vasconcellos, Juliani C. R. Araujo, Gujie Mi, Paria Ghannadian, Tatiane Toniato, Fernanda R. Marciano, Thomas J. Webster, Anderson O. Lobo
Summary: In this study, a next-generation bone regeneration material was developed by combining polycaprolactone fibers, carbon nanotubes, and hydroxyapatite nanoparticles. Rotary jet spinning fibers showed the best outcomes in repairing rat calvarial defects, and their rough topography allowed for better cellular growth and spreading. Incorporating nanoparticles and bone marrow mesenchymal stem cells enhanced cell performance and resulted in greater bone neoformation.
ACS APPLIED BIO MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Patricia Capellato, Lucas V. B. Vasconcelos, Filipe B. Vilela, Gilza Carla Ribeiro, Cristiane A. P. Correia, Gilbert Silva, Daniela Sachs, Andre L. R. Rangel, Cecilia A. de C. Zavaglia, Ana P. R. Alves Claro
Summary: This study performed two combined surface modifications on Ti-30Ta alloy to obtain an infection-resistance and osseointegration surface on metallic implants. Results indicated that Group 1 showed higher antimicrobial activity and hydrophilic behavior, suitable for metallic implant applications, while Group 2 with hydroxyapatite film coating did not improve the antimicrobial response.
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2021)
