Discovery of DNA Topoisomerase I Inhibitors with Low-Cytotoxicity Based on Virtual Screening from Natural Products

Topsensterols A–C, Cytotoxic Polyhydroxylated Sterol Derivatives from a Marine Sponge Topsentia sp.

(2016) Min Chen et al.   Marine Drugs

cyp51A-based mechanism of azole resistance inAspergillus fumigatus: Illustration by a new 3D Structural Model ofAspergillus fumigatusCYP51A protein

(2016) Musang Liu et al.   MEDICAL MYCOLOGY

Chromone Derivatives from a Sponge-Derived Strain of the Fungus Corynespora cassiicola

(2015) Dong-Lin Zhao et al.   JOURNAL OF NATURAL PRODUCTS

Cytotoxic scalarane sesterterpenoids from the South China Sea sponge Carteriospongia foliascens

(2015) Fei Cao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II

(2013) Shi-Tian Zhuo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bioactive Hydroanthraquinones and Anthraquinone Dimers from a Soft Coral-Derived Alternaria sp. Fungus

(2012) Cai-Juan Zheng et al.   JOURNAL OF NATURAL PRODUCTS

Structure-Based Design, Synthesis, and Biological Studies of New Anticancer Norindenoisoquinoline Topoisomerase I Inhibitors

(2010) Yunlong Song et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

(2010) Guoqiang Dong et al.   JOURNAL OF MEDICINAL CHEMISTRY

DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

(2009) Yves Pommier   CHEMICAL REVIEWS

Design, Synthesis and Development of Novel Camptothecin Drugs

(2008) Siong Liew et al.   CURRENT PHARMACEUTICAL DESIGN