Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines

Uveale Melanomzellen unter oxidativem Stress – Einfluss von VEGF und VEGF-Inhibitoren

(2017) M. Dithmer et al.   KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE

The natural compound fucoidan from New Zealand Undaria pinnatifida synergizes with the ERBB inhibitor lapatinib enhancing melanoma growth inhibition

(2017) Varsha Thakur et al.   Oncotarget

A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4

(2016) Wucheng Wang et al.   CARBOHYDRATE POLYMERS

A review about the development of fucoidan in antitumor activity: Progress and challenges

(2016) Lei Wu et al.   CARBOHYDRATE POLYMERS

Antitumor activity of fucoidan against diffuse large B cell lymphomain vitroandin vivo

(2015) Guang Yang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling

(2015) Yong-seok Han et al.   Biomolecules & Therapeutics

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

(2015) Isaac S. Harris et al.   CANCER CELL

Melanoma of the eye: Revealing hidden secrets, one at a time

(2015) Carol L. Shields et al.   CLINICS IN DERMATOLOGY

Fucoidan protects mesenchymal stem cells against oxidative stress and enhances vascular regeneration in a murine hindlimb ischemia model

(2015) Yong-seok Han et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Effects of fucoidan on proliferation, AMP-activated protein kinase, and downstream metabolism- and cell cycle-associated molecules in poorly differentiated human hepatoma HLF cells

(2015) TAKUMI KAWAGUCHI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Prophylactic Administration of Fucoidan Represses Cancer Metastasis by Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs) in Lewis Tumor-Bearing Mice

(2015) Tse-Hung Huang et al.   Marine Drugs

Fucoidan and Cancer: A Multifunctional Molecule with Anti-Tumor Potential

(2015) Farzaneh Atashrazm et al.   Marine Drugs

Fucoidan protects ARPE-19 cells from oxidative stress via normalization of reactive oxygen species generation through the Ca2+-dependent ERK signaling pathway

(2015) XIAOXIA LI et al.   Molecular Medicine Reports

Oxidative stress inhibits distant metastasis by human melanoma cells

(2015) Elena Piskounova et al.   NATURE

Management of Posterior Uveal Melanoma: Past, Present, and Future

(2015) Jerry A. Shields et al.   OPHTHALMOLOGY

Anticancer Effect of Fucoidan in Combination with Tyrosine Kinase Inhibitor Lapatinib

(2014) Byeongsang Oh et al.   Evidence-based Complementary and Alternative Medicine

Hyperthermia-induced upregulation of vascular endothelial growth factor in retinal pigment epithelial cells is regulated by mitogen-activated protein kinases

(2014) Hendrik Faby et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Fucoidan Inhibits the Proliferation of Human Urinary Bladder Cancer T24 Cells by Blocking Cell Cycle Progression and Inducing Apoptosis

(2014) Hye Park et al.   MOLECULES

Fucoidan Reduces Secretion and Expression of Vascular Endothelial Growth Factor in the Retinal Pigment Epithelium and Reduces Angiogenesis In Vitro

(2014) Michaela Dithmer et al.   PLoS One

AKT signaling is involved in fucoidan-induced inhibition of growth and migration of human bladder cancer cells

(2013) Tae-Min Cho et al.   FOOD AND CHEMICAL TOXICOLOGY

Fucoidan Extract Enhances the Anti-Cancer Activity of Chemotherapeutic Agents in MDA-MB-231 and MCF-7 Breast Cancer Cells

(2013) Zhongyuan Zhang et al.   Marine Drugs

Induction of Apoptosis by Fucoidan in Human Leukemia U937 Cells through Activation of p38 MAPK and Modulation of Bcl-2 Family

(2013) Hyun Park et al.   Marine Drugs

The Anticancer Effect of Fucoidan in PC-3 Prostate Cancer Cells

(2013) Hye-Jin Boo et al.   Marine Drugs

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

The role of Bax and Bcl-2 in gemcitabine-mediated cytotoxicity in uveal melanoma cells

(2013) Jing Wang et al.   TUMOR BIOLOGY

Uveal melanoma

(2012) Francesco Spagnolo et al.   CANCER TREATMENT REVIEWS

Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells

(2012) Fang Liu et al.   PHYTOMEDICINE

Impact of Combined mTOR and MEK Inhibition in Uveal Melanoma Is Driven by Tumor Genotype

(2012) Alan L. Ho et al.   PLoS One

Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer In Vitro and In Vivo

(2012) Meilan Xue et al.   PLoS One

Fucoidan from Seaweed Fucus vesiculosus Inhibits Migration and Invasion of Human Lung Cancer Cell via PI3K-Akt-mTOR Pathways

(2012) Hyunkyoung Lee et al.   PLoS One

Natural withanolide withaferin A induces apoptosis in uveal melanoma cells by suppression of Akt and c-MET activation

(2012) Abbas K. Samadi et al.   TUMOR BIOLOGY

Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo

(2011) Marcel Tutor Ale et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fucose-Containing Sulfated Polysaccharides from Brown Seaweeds Inhibit Proliferation of Melanoma Cells and Induce Apoptosis by Activation of Caspase-3 in Vitro

(2011) Marcel Tutor Ale et al.   Marine Drugs

Apoptosis Inducing Activity of Fucoidan in HCT-15 Colon Carcinoma Cells

(2009) Jae-Hee Hyun et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Dynamic processes involved in the pre-vascularization of silk fibroin constructs for bone regeneration using outgrowth endothelial cells

(2008) Sabine Fuchs et al.   BIOMATERIALS