Journal
MARINE DRUGS
Volume 15, Issue 4, Pages -Publisher
MDPI AG
DOI: 10.3390/md15040088
Keywords
marine protein; bioactive peptide; regulation; glucose metabolism; structure active relationship
Categories
Funding
- National Natural Science Foundation of China [81302416]
- Guangdong Science and Technology Planning Project [2014A020212297]
- Guangdong Training Plan for Outstanding Young Teachers [YQ201405]
- Dongguan Science and Technology Planning Project [2014108101053]
- Dongguan Key Laboratory of Environmental Medicine
Ask authors/readers for more resources
An increasing prevalence of diabetes is known as a main risk for human health in the last future worldwide. There is limited evidence on the potential management of type 2 diabetes mellitus using bioactive peptides from marine organisms, besides from milk and beans. We summarized here recent advances in our understanding of the regulation of glucose metabolism using bioactive peptides from natural proteins, including regulation of insulin-regulated glucose metabolism, such as protection and reparation of pancreatic beta-cells, enhancing glucose-stimulated insulin secretion and influencing the sensitivity of insulin and the signaling pathways, and inhibition of bioactive peptides to dipeptidyl peptidase IV, alpha-amylase and alpha-glucosidase activities. The present paper tried to understand the underlying mechanism involved and the structure characteristics of bioactive peptides responsible for its antidiabetic activities to prospect the utilization of rich marine organism proteins.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available