Journal
MARINE DRUGS
Volume 15, Issue 7, Pages -Publisher
MDPI AG
DOI: 10.3390/md15070230
Keywords
deep-sea; actinomycete; Microbacterium sp.; indole
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Funding
- Science & Technology Research Program of Fujian Province, China [2017Y0060]
- National Natural Science Foundation of China [41676130, 41606185, 21372233]
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A novel indole, microindolinone A (1), was isolated from a deep-sea-derived actinomycete Microbacterium sp. MCCC 1A11207, together with 18 known compounds (2-19). By detailed analysis of the H-1, C-13, HSQC, COSY, HMBC, high resolution electron spray ionization mass spectrum (HRESIMS), and circular dichroism (CD) data, the absolute configuration of 1 was elucidated as 5R-hydroxy-4,5,6,7-tetrahydroindole-4-one. It is noteworthy that 1 is the second example of a saturated indole isolated from nature.
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