Article
Polymer Science
Patricia R. Calvo, Chelsea A. Sparks, Justin Hochberg, Kenneth B. Wagener, Brent S. Sumerlin
Summary: Hyperbranched aminobisphosphonic acid polymers were synthesized via RAFT self-condensing vinyl polymerization. A novel acrylamide-functional chain transfer monomer and a 3-component Kabachnik-Fields reaction were used to introduce functional groups, creating acid-degradable imine hydrogels.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Polymer Science
Samet Guner, Mustafa Ciftci
Summary: A versatile method for synthesizing polystyrene based hyperbranched polymers with tunable branching densities was reported. This method combines self-condensing vinyl polymerization and iniferter processes using a dual functional monomer, 2,2,2-(triphenylethyl)styrene. The branching densities of the polymers can be regulated by adjusting the concentration of the monomer and the polymerization time. The obtained polymers were further used as macroiniferters for the copolymerization of a hydrophilic monomer, poly(ethylene glycol) acrylate, to produce amphiphilic branched-core star polymers.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Polymer Science
Semira Bener, Cansu Aydogan, Yusuf Yagci
Summary: A novel approach for the synthesis of hyperbranched polymers using photoinduced self-condensing vinyl polymerization has been explored, leading to successful production of HBPs with different branching densities. This method has potential applications in various fields, especially in bio-related systems requiring highly branched structures without contamination of low-molar mass photoinitiator fragments.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2021)
Article
Polymer Science
Li-Han Rong, Xiang Cheng, Jin Ge, Eugene B. Caldona, Rigoberto C. Advincula
Summary: Photoinduced polymerization techniques, particularly combining RAFT with SCVP, were used to prepare hyperbranched polymers in a flow reactor under extremely mild conditions in this study. The use of a flow reactor showed improved scalability, reliability, and efficiency, allowing for the synthesis of block copolymers with considerable controllability in molecular weight and branching density by adjusting the feeding ratio of monomer to transmer.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2022)
Article
Polymer Science
Weibin Cai, Shuaiqi Yang, Lunqiang Zhang, Ying Chen, Li Zhang, Jianbo Tan
Summary: Efficient synthesis and self-assembly of segmented hyperbranched block copolymers (SHBCs) were achieved using reversible addition-fragmentation chain-transfer (RAFT)-mediated dispersion polymerization-induced self-assembly (PISA) method. Different synthetic approaches were employed to obtain SHBCs with significant structural differences, and further control over the structure and morphology of SHBCs and SHBC assemblies was achieved.
Article
Polymer Science
Weibin Cai, Shuaiqi Yang, Lunqiang Zhang, Ying Chen, Li Zhang, Jianbo Tan
Summary: In this work, efficient synthesis and self-assembly of segmented hyperbranched block copolymers (SHBCs) were achieved using segmented hyperbranched macro-RAFT agents. The Z-RAFT approach allowed the solvophobic block to grow inside SHBCs, leading to the synthesis of colloidally stable SHBC assemblies with various morphologies. By combining different approaches, further structural and morphological control over SHBCs and SHBC assemblies were achieved. This work not only provides a facile method for the efficient synthesis of SHBCs and SHBC assemblies but also offers important insights into the PISA process of nonlinear block copolymers.
Article
Polymer Science
Yue Zhang, Rong Zhao, Yan Qin, Jianguo Yi, Jimin Zhang, Xiaoai Chen
Summary: Light-induced metal-free atom transfer radical polymerization (ATRP) combined with self-condensing vinyl polymerization (SCVP) was used to prepare hyperbranched multiarm copolymers for peptide conjugation. The hyperbranched copolymers were synthesized by copolymerizing di(ethylene glycol) methyl ether methacrylate (DEGMA) and 2-(2-bromo-2-methylpropanoyloxy)ethyl methacrylate (BMA) through metal-free ATRP. Further polymerization of pyridyl disulfide ethyl methacrylate (DSMA) with the hyperbranched polymers as macroinitiator resulted in hyperbranched multiarm copolymers. Glutathione and cysteine-modified targeting peptide were conjugated to the hyperbranched copolymers, and their self-assembly behaviors were investigated.
Article
Polymer Science
Lu Wang, Yongliang Zhan, Linhui Zhang, Hongkun Li
Summary: Efficient polymerization strategies are crucial in polymer science. Metal-free polycyclotrimerization of internal diynes has been successfully achieved to synthesize regioregular hyperbranched polyarylenes (hb-PAs). The resulting hb-PAs exhibit high molecular weights, perfect regioregularity, thermal stabilities, and electrochemical activities. Moreover, they display aggregation-induced emission properties.
Article
Chemistry, Multidisciplinary
Neng Yang, Yu Jiang, Qinwen Tan, Jiahui Ma, Dezhi Zhan, Zhaohong Wang, Xin Wang, Daohong Zhang, Nikos Hadjichristidis
Summary: An efficient one-pot strategy for the structure-controlled synthesis of hyperbranched polymers (HBPs) has been developed. By using a latent inimer and regulating the temperature or stereochemistry, the release of maleimide (MI) and subsequent copolymerization can be controlled, leading to the synthesis of HBPs with various degrees of branching.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Polymer Science
Xiaoqing Ai, Jiansen Pan, Qingyi Xie, Chunfeng Ma, Guangzhao Zhang
Summary: A cleavable hyperbranched polymer with vinyl groups was developed for use in adhesives and coatings, exhibiting excellent antifouling properties. The polymer effectively inhibits the adhesion of proteins, marine bacteria, and diatoms, making it suitable for marine antifouling applications.
Article
Polymer Science
Ramon Novoa-Carballal, Sergey Nosov, Sandrine Pfaff, Holger Schmalz, Axel H. E. Mueller
Summary: Highly branched polybutadienes were successfully synthesized via ASCVCP method, with SEC/viscosity measurements confirming the branched structure of the obtained polymers. Differences in mechanism were observed in the polymerization of two isomers of divinylbenzene. The living nature of the polymerization allowed further amino-functionalization or growth of (meth)acrylate arms, leading to hyperstar molecules.
Article
Materials Science, Multidisciplinary
Sahand Rahemipoor, Mohammad Kohestanian, Ali Pourjavadi, Hossein Heidarzadeh Vazifehkhorani, Mehdi Mehrali
Summary: Multistimuli-responsive hyperbranched polymers were successfully synthesized in one step using RAFT-SCVP, showing controlled properties for potential sensor applications.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Sahand Rahemipoor, Mohammad Kohestanian, Ali Pourjavadi, Hossein Heidarzadeh Vazifehkhorani, Mehdi Mehrali
Summary: In this study, multistimuli-responsive hyperbranched polymers were successfully synthesized in one step using the RAFT-SCVP method, allowing for control of molecular weights and degree of branching. These smart hyperbranched polymers exhibit responses to various stimuli such as UV-vis or sunlight, pH changes, and temperature changes.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Polymer Science
Sun Hwa Lee, Jae Hong Seo, Eunhye Shin, Se Hun Joo, Onur Buyukcakir, Yi Jiang, Minhyeok Kim, Hyunju Nam, Sang Kyu Kwak, Rodney S. Ruoff
Summary: We describe a method for structural analysis of a hyperbranched polyhydrocarbon (PHC) synthesized by electrochemical polymerization. Experimental techniques including NMR, elemental analysis and FTIR were used to determine the polymer's structure, and a simulated structure was also developed. The results showed good agreement between the experimental and simulated values for density, refractive index, melting temperature, and IR spectrum. The calculated solubility parameters rationalized the observed solubility in different solvents at room temperature. This comprehensive elucidation of the structure of a randomly branched polymer using experimental and theoretical methods is a significant contribution and has potential for wide application in the future.
Article
Polymer Science
Quan Long, Xia Li, Yawen Huang, Qiuxia Peng, Xian Li, Liangbo Zhu, Jiajun Ma, Xu Ye, Junxiao Yang
Summary: This paper investigates the effect of spacing groups on the physicochemical properties of hyperbranched polycarbosilane derived resins by synthesizing hyperbranched polycarbosilanes with reactive benzocyclobutene groups. It is found that phenyl groups can effectively decrease the dielectric constant of the resins while maintaining good film forming ability and thermostability.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Zeynep Deliballi, Rezan Demir-Cakan, Baris Kiskan, Yusuf Yagci
Summary: A new approach to vulcanize commercial PVC at room temperature using elemental sulfur and an initiator is reported. The obtained crosslinked polymer with polysulfide linkages shows potential for recycling/self-healing and as cathode material for Li-S battery.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2023)
Article
Biochemistry & Molecular Biology
Zehra Gul Coban, Huseyin Cem Kiliclar, Yusuf Yagci
Summary: Photochemical techniques have seen a revival due to their adaptability and ability to produce complex macromolecular structures, although their application in the polymerization of cyclic siloxane monomers has been limited. This study investigated the cationic ring-opening polymerization of Octamethylcyclotetrasiloxane (D4) using diphenyl iodonium hexafluorophosphate (DPI) as the initiator. Both direct and indirect initiation systems were examined, using benzophenone and pyrene to generate photochemically induced protonic acids and silylium cations for the polymerization. Kinetics of the polymerization were monitored using viscosimetry and GPC analysis. This approach has potential industrial importance for polysiloxane fabrication due to its ability to overcome challenges associated with conventional methods.
Article
Multidisciplinary Sciences
Caner Geyik, Zinar Pinar Gumus, Gorkem Yararbas
Summary: Electronic cigarettes have gained popularity globally, but their effects on human health are still not well-known. This study aimed to analyze the contents of widely used e-liquids and their effects on two different cell lines.
TRAKYA UNIVERSITY JOURNAL OF NATURAL SCIENCES
(2023)
Article
Chemistry, Analytical
Huseyin Furkan Kiyikci, Okan Avci, Yudum Tepeli Buyuksunetci, Suna Timur, Ulku Anik
Summary: A facile amperometric biosensor was developed using a Co/2Fe metal-organic framework (MOF) with oxidase mimicking properties for the detection of sialic acid (SA). The biosensor was constructed by immobilizing Co/2Fe MOF and N-acetylneuraminic Acid Aldolase (NANA-Aldolase) enzyme on a gold screen-printed electrode. The sensor showed a linear range of 0.02 mM-1.00 mM for SA concentration and a limit of detection of 0.026 mM. The developed biosensor was successfully applied for the detection of SA in GD3 ganglioside and HeLa cancer cell lines, providing a more practical and accurate system.
Review
Chemistry, Multidisciplinary
Faezeh Ghorbanizamani, Hichem Moulahoum, Emine Guler Celik, Suna Timur
Summary: The growing demand for personalized treatments and constant vital signs observation has led to the development of implantable biosensors that can temporarily or permanently be introduced into the human body. However, ensuring reliable functionality in the complex environment of the human body remains a critical challenge.
APPLIED SCIENCES-BASEL
(2023)
Review
Chemistry, Analytical
Bilge Asci Erkocyigit, Ozge Ozufuklar, Aysenur Yardim, Emine Guler Celik, Suna Timur
Summary: Microfluidics plays a crucial role in lab-on-a-chip systems, allowing for manipulation of fluid behavior and control on a small platform. Paper-based microfluidic analytical devices (muPADs) have numerous advantages, especially in cancer biomarker detection, and have the potential to improve diagnosis and treatment outcomes.
Review
Chemistry, Analytical
Nur Melis Kilic, Sima Singh, Gulsu Keles, Stefano Cinti, Sevinc Kurbanoglu, Dilek Odaci
Summary: Electrochemistry is an interdisciplinary science that has applications in various domains. The use of biosensors to measure biological or biochemical processes is critical in medical and biotechnological fields. There are electrochemical biosensors available for healthcare applications such as glucose, lactate, and nucleic acid detection. Enzyme-based biosensors using carbon-based nanomaterials are highly sensitive and selective, with fast reaction times. However, they can be influenced by environmental factors and the cost of enzymes and their immobilization can hinder their widespread use. This review discusses the design and applications of enzyme-based electrochemical nanobiosensors.
Review
Chemistry, Analytical
Faezeh Ghorbanizamani, Hichem Moulahoum, Emine Guler Celik, Figen Zihnioglu, Tutku Beduk, Tuncay Goksel, Kutsal Turhan, Suna Timur
Summary: Minimally invasive approaches in cancer diagnosis, such as liquid biopsies using blood samples, provide valuable information about the tumor and its state. However, isolating and detecting markers in complex matrices is challenging. Advances in polymer synthesis have led to enhanced platforms for liquid biopsies analysis, improving biosensor performance through increased sensitivity, improved binding, and avoidance of non-specific interactions. Additionally, polymer-based materials aid in signal amplification for low-concentration targets. This technology plays an essential role in oncology and clinical biomedicine, as shown by its critical application in liquid biopsies diagnosis.
Review
Nanoscience & Nanotechnology
Mohd. Rahil Hasan, Pradakshina Sharma, Shariq Suleman, Shouvik Mukherjee, Emine Guler Celik, Suna Timur, Roberto Pilloton, Jagriti Narang
Summary: Integrating electronic applications with paper can expand the uses of paper substrates, but putting electronics on paper is not easy. However, methods like building electronic devices on a rough, absorbent surface of the paper have made significant progress in paper electronics.
ACS APPLIED BIO MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Haluk Celik, Balim Bengisu Caf, Caner Geyik, Gizem Cebi, Miray Tayfun
Summary: The translated article introduces the advantages of point-of-care diagnostics (POC) and urine test strips, as well as the importance of urine analysis in evaluating health conditions. It also explores the impact of dietary intake on urine biomarkers and recent developments in related technologies.
Review
Nanoscience & Nanotechnology
Mohd Rahil Hasan, Pradakshina Sharma, Shariq Suleman, Shouvik Mukherjee, Emine Guler Celik, Suna Timur, Roberto Pilloton, Jagriti Narang
Summary: Integrating electronic applications with paper substrates can expand the potential uses of paper. While paper has advantages such as being disposable, inexpensive, and environmentally friendly, its rough and porous surface poses a challenge for putting electronics on paper. However, there are methods to make electronic devices compatible with the absorbent surface of paper.
ACS APPLIED BIO MATERIALS
(2023)
