Rare, high-affinity mouse anti-PD-1 antibodies that function in checkpoint blockade, discovered using microfluidics and molecular genomics

Single amino acid fingerprinting of the human antibody repertoire with high density peptide arrays

(2017) Laura K. Weber et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Selection of therapeutic H5N1 monoclonal antibodies following IgVH repertoire analysis in mice

(2016) Sean A. Gray et al.   ANTIVIRAL RESEARCH

Highly Accurate Sequencing of Full-Length Immune Repertoire Amplicons Using Tn5-Enabled and Molecular Identifier–Guided Amplicon Assembly

(2016) Charles Cole et al.   JOURNAL OF IMMUNOLOGY

Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VLlibraries from immunized animals

(2016) Bo Wang et al.   mAbs

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

(2016) Vassiliki A. Boussiotis   NEW ENGLAND JOURNAL OF MEDICINE

Clonify: unseeded antibody lineage assignment from next-generation sequencing data

(2016) Bryan Briney et al.   Scientific Reports

Error filtering, pair assembly and error correction for next-generation sequencing reads

(2015) Robert C. Edgar et al.   BIOINFORMATICS

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining

(2015) Bo Wang et al.   Scientific Reports

High-throughput epitope binning of therapeutic monoclonal antibodies: why you need to bin the fridge

(2014) Benjamin D. Brooks et al.   DRUG DISCOVERY TODAY

A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes

(2014) Edgar Davidson et al.   IMMUNOLOGY

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

(2014) Brandon J DeKosky et al.   NATURE MEDICINE

Diversity of the murine antibody response targeting influenza A(H1N1pdm09) hemagglutinin

(2014) Jason R. Wilson et al.   VIROLOGY

Novel Recombinant Human B7-H4 Antibodies Overcome Tumoral Immune Escape to Potentiate T-Cell Antitumor Responses

(2013) D. Dangaj et al.   CANCER RESEARCH

Single-cell based high-throughput sequencing of full-length immunoglobulin heavy and light chain genes

(2013) Christian E. Busse et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

UPARSE: highly accurate OTU sequences from microbial amplicon reads

(2013) Robert C Edgar   NATURE METHODS

Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining

(2012) I. Saggy et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Rapid Generation of Rotavirus-Specific Human Monoclonal Antibodies from Small-Intestinal Mucosa

(2010) R. Di Niro et al.   JOURNAL OF IMMUNOLOGY

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

(2010) Sai T Reddy et al.   NATURE BIOTECHNOLOGY

Development trends for human monoclonal antibody therapeutics

(2010) Aaron L. Nelson et al.   NATURE REVIEWS DRUG DISCOVERY

Efficient Recovery of High-Affinity Antibodies from a Single-Chain Fab Yeast Display Library

(2009) Laura M. Walker et al.   JOURNAL OF MOLECULAR BIOLOGY

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH