Article
Agriculture, Dairy & Animal Science
Marnie J. Hodge, Sara de las Heras-Saldana, Sally J. Rindfleish, Cyril P. Stephen, Sameer D. Pant
Summary: This study aimed to identify genomic regions and associated genes that may significantly influence semen traits in Merino sheep. A total of 35 quantitative trait loci (QTLs) were identified to be significantly associated with semen traits, and 290 candidate genes were found within these QTLs. The validation of these candidate genes could provide valuable insights into improving sheep reproductive efficiency.
Article
Biotechnology & Applied Microbiology
Xiurong Zhao, Changsheng Nie, Jinxin Zhang, Xinghua Li, Tao Zhu, Zi Guan, Yu Chen, Liang Wang, Xue Ze Lv, Weifang Yang, Yaxiong Jia, Zhonghua Ning, Haiying Li, Changqing Qu, Huie Wang, Lujiang Qu
Summary: This study utilized genome-wide association study to identify 148 SNPs associated with egg number traits and 32 candidate genes related to hormone regulation, follicle development, and reproductive system development. The study also highlighted a genomic region on GGA5 as a potential candidate region underlying egg number traits.
Article
Genetics & Heredity
Donglin Ruan, Zhanwei Zhuang, Rongrong Ding, Yibin Qiu, Shenping Zhou, Jie Wu, Cineng Xu, Linjun Hong, Sixiu Huang, Enqin Zheng, Gengyuan Cai, Zhenfang Wu, Jie Yang
Summary: A weighted single-step genome-wide association study was conducted to identify genetic regions associated with growth traits in pigs, with the most significant regions explaining a substantial portion of genetic variance. Twenty-one candidate genes related to metabolism, bone growth, and fat deposition were identified, and they were found to be involved in bone formation, the immune system, and digestion. Utilizing phenotypic, genotypic, and genealogical information will aid in accelerating genetic improvement of growth traits in pigs.
Article
Agriculture, Dairy & Animal Science
Mei Liu, Qun Lan, Long Yang, Qiuchun Deng, Taiyun Wei, Heng Zhao, Peiya Peng, Xiaoding Lin, Yuhan Chen, Haiming Ma, Hongjiang Wei, Yulong Yin
Summary: The aim of this study was to identify the genetic loci and candidate genes associated with phenotypic traits in DSE pigs using GWAS. Seven SNPs were found to be significantly associated with back height, chest circumference, cannon bone circumference, and backfat thickness. These SNPs were mapped to candidate genes involved in adipocyte differentiation, lipid metabolism, skeletal muscle development, and average daily weight gain. This study provides new insights into the genetic architecture of economically important traits in swine and has implications for molecular marker breeding in the DSE breed.
Article
Agriculture, Dairy & Animal Science
Herman Alberto Revelo, Diana Lopez-Alvarez, Yineth Alexandra Palacios, Oscar David Vergara, Moris Bustamante Yanez, Manuel Fernando Ariza, Susan Lorena Castro Molina, Yurany Ortiz Sanchez, Luz angela Alvarez
Summary: This study conducted a genome-wide association study on meat quality traits using GWAS and identified 11 candidate genes associated with water-holding capacity. It provided a baseline for future GWAS research on meat quality traits in Colombian hair sheep.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2023)
Article
Biochemistry & Molecular Biology
Tianzhen Wang, Qunhao Niu, Tianliu Zhang, Xu Zheng, Haipeng Li, Xue Gao, Yan Chen, Huijiang Gao, Lupei Zhang, George E. Liu, Junya Li, Lingyang Xu
Summary: This study conducted an integrative analysis of gene-based GWAS and eQTL analysis to identify candidate genes for carcass yield traits in beef cattle. The results revealed shared genes that may play important roles in carcass yield traits and further demonstrated the effects of two genes, PON3 and PRIM2, on the proliferation and differentiation of bovine skeletal muscle satellite cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Food Science & Technology
N. A. Marin-Garzon, A. F. B. Magalhaes, L. F. M. Mota, L. F. S. Fonseca, L. A. L. Chardulo, L. G. Albuquerque
Summary: This study in Nellore cattle identified candidate genes and genomic regions associated with meat color traits through single and multiple-trait GWAS, explaining genetic variance rates and confirming pleiotropic effects in certain regions. The research was conducted using the single-step GWAS method and the BLUPF90 family programs.
Article
Biochemistry & Molecular Biology
Qibao Liu, Zhen Feng, Chenjue Huang, Jia Wen, Libei Li, Shuxun Yu
Summary: Genomic regions and candidate genes related to cotton senescence were explored through genome-wide association studies, with the discovery of GhMKK9 as a potential positive regulator involved in drought-induced senescence in cotton.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Fisheries
Xin He, Yushan Liao, Zexin Yang, Hongxing Liu, Shi Wang, Yongbo Bao
Summary: The blood clam Tegillarca granosa is a commercially important bivalve species. This study conducted genome-wide association studies and identified 39 SNP markers associated with the growth traits of T. granosa. Additionally, 27 candidate genes potentially involved in T. granosa growth were identified. Enrichment analysis highlighted the role of transmembrane transport, immune system function, protein family metabolism, and JAK-STAT signaling pathways in T. granosa growth.
Article
Biotechnology & Applied Microbiology
Hongchang Zhao, Tingting Guo, Zengkui Lu, Jianbin Liu, Shaohua Zhu, Guoyan Qiao, Mei Han, Chao Yuan, Tianxiang Wang, Fanwen Li, Yajun Zhang, Fujun Hou, Yaojing Yue, Bohui Yang
Summary: This study conducted re-sequencing of 460 sheep from four different fine-wool sheep breeds and identified candidate genes and SNPs associated with wool traits. These findings provide a significant theoretical basis for breeding fine-wool sheep.
Article
Biochemistry & Molecular Biology
Jun Xiang, Chaopu Zhang, Nansheng Wang, Zhaojie Liang, Zheng Zhenzhen, Lunping Liang, Hongyan Yuan, Yingyao Shi
Summary: Root architecture is a determinant factor of drought resistance in rice. This study identified 13 quantitative trait loci and 19 genetic interactions associated with root-related traits, providing important genomic resources for improving stress-resistance and grain yield in rice breeding.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2022)
Article
Plant Sciences
Qibao Liu, Libei Li, Zhen Feng, Shuxun Yu
Summary: This study revealed the genetic basis of cotton senescence through genome-wide association studies and identified multiple genomic regions and candidate genes associated with cotton senescence.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Libei Li, Yu Hu, Yongbo Wang, Shuqi Zhao, Yijin You, Ruijie Liu, Jiayi Wang, Mengyuan Yan, Fengli Zhao, Juan Huang, Shuxun Yu, Zhen Feng
Summary: In this study, significant SNPs and candidate genes related to seed vigor traits in cotton were identified using high-quality SNP data. Two novel candidate genes associated with seed vigor were discovered through gene expression, annotation, and haplotype analysis. The findings contribute to the improvement of direct seeding efficiency through molecular marker-assisted breeding.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Genetics & Heredity
Shuang Song, Shiwei Wang, Nan Li, Siyu Chang, Shizhen Dai, Yajun Guo, Xuan Wu, Yuanweilu Cheng, Shenming Zeng
Summary: This study identified genomic variations associated with body size traits in Yangyuan donkeys, providing useful information for breeding and functional gene studies.
FRONTIERS IN GENETICS
(2023)
Article
Genetics & Heredity
Huiling Zhao, Ruizheng Tian, Han Xia, Changsheng Li, Guanghui Li, Aiqin Li, Xianying Zhang, Ximeng Zhou, Jing Ma, Huailing Huang, Kun Zhang, Mahendar Thudi, Changle Ma, Xingjun Wang, Chuanzhi Zhao
Summary: This study establishes a comprehensive genome variation map based on the genotyping of 178 peanut cultivars, and identifies marker-trait associations and candidate genes related to agronomic traits of peanut. It also provides a large number of polymorphic SNP markers for further distinguishing and utilizing elite cultivars, and valuable information for improving the quality and yield of peanut using a genomic-assisted breeding method.
FRONTIERS IN GENETICS
(2022)
Article
Agriculture, Dairy & Animal Science
Hamed Asadollahi, Saeid Ansari Mahyari, Rasoul Vaez Torshizi, Hossein Emrani, Alireza Ehsani
Summary: This study evaluated the population structure of an F2 population derived from Arian and Urmia chickens using genome-wide analysis, clustering the chickens into eight sub-populations with relatively high genetic variability.
ANIMAL SCIENCE PAPERS AND REPORTS
(2021)
Article
Biotechnology & Applied Microbiology
Hossein Emrani, Cyrus Amirinia, Mohammad Ali Radjaee Arbabe
AFRICAN JOURNAL OF BIOTECHNOLOGY
(2011)
Article
Agriculture, Dairy & Animal Science
Adrian Lopez-Catalina, Valentin Costes, Ramon Peiro-Pastor, Helene Kiefer, Oscar Gonzalez-Recio
Summary: Epigenetic marks can explain part of the phenotypic variance in animal breeding models. Nanopore sequencing shows high correlation with bisulphite sequencing in identifying DNA methylation marks. Different sequencing methods highlight differentially methylated genes and positions of economic interest in animal breeding.