Mucosal-associated invariant T-cell frequency and function in blood and liver of HCV mono- and HCV/HIV co-infected patients with advanced fibrosis

Nonreversible MAIT cell-dysfunction in chronic hepatitis C virus infection despite successful interferon-free therapy

(2016) Julia Hengst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human MAIT-cell responses to Escherichia coli : activation, cytokine production, proliferation, and cytotoxicity

(2016) Joana Dias et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mucosa-Associated Invariant T Cells Are Systemically Depleted in Simian Immunodeficiency Virus-Infected Rhesus Macaques

(2016) Carol Vinton et al.   JOURNAL OF VIROLOGY

The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013

(2016) Jeffrey D Stanaway et al.   LANCET

Prevalence and burden of HCV co-infection in people living with HIV: a global systematic review and meta-analysis

(2016) Lucy Platt et al.   LANCET INFECTIOUS DISEASES

Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

(2016) Michelle Spaan et al.   PLoS One

MAIT cells are activated during human viral infections

(2016) Bonnie van Wilgenburg et al.   Nature Communications

Successful Interferon-Free Therapy of Chronic Hepatitis C Virus Infection Normalizes Natural Killer Cell Function

(2015) Elisavet Serti et al.   GASTROENTEROLOGY

Natural history and treatment of HCV/HIV coinfection: Is it time to change paradigms?

(2015) Joop E. Arends et al.   JOURNAL OF HEPATOLOGY

The Intrahepatic T Cell Compartment Does Not Normalize Years After Therapy-Induced Hepatitis C Virus Eradication

(2015) Michelle Spaan et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular Analyses Define Vα7.2-Jα33+ MAIT Cell Depletion in HIV Infection

(2015) James E. Ussher et al.   MEDICINE

Attrition of TCR Vα7.2+ CD161++ MAIT Cells in HIV-Tuberculosis Co-Infection Is Associated with Elevated Levels of PD-1 Expression

(2015) Alireza Saeidi et al.   PLoS One

Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection

(2015) Edwin Leeansyah et al.   PLoS Pathogens

MAIT cells are depleted early but retain functional cytokine expression in HIV infection

(2014) Caroline S Fernandez et al.   IMMUNOLOGY AND CELL BIOLOGY

Restoration of HCV-specific CD8+ T cell function by interferon-free therapy

(2014) Bianca Martin et al.   JOURNAL OF HEPATOLOGY

Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection

(2014) Emily B. Wong et al.   PLoS One

CD161+ MAIT Cells Are Severely Reduced in Peripheral Blood and Lymph Nodes of HIV-Infected Individuals Independently of Disease Progression

(2014) Johanna Maria Eberhard et al.   PLoS One

Toll-Like Receptor 8 Agonist and Bacteria Trigger Potent Activation of Innate Immune Cells in Human Liver

(2014) Juandy Jo et al.   PLoS Pathogens

Mucosal-Associated Invariant T-Cells: New Players in Anti-Bacterial Immunity

(2014) James E. Ussher et al.   Frontiers in Immunology

CD161++CD8+T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner

(2013) James E. Ussher et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

(2013) Rangsima Reantragoon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells

(2013) X.-Z. Tang et al.   JOURNAL OF IMMUNOLOGY

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

(2013) Onisha Patel et al.   Nature Communications

MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells

(2013) Lionel Le Bourhis et al.   PLoS Pathogens

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

(2012) E. Leeansyah et al.   BLOOD

Early and nonreversible decrease of CD161++/MAIT cells in HIV infection

(2012) C. Cosgrove et al.   BLOOD

All-cause and liver-related mortality in HIV positive subjects compared to the general population: Differences by HCV co-infection

(2012) Victoria Hernando et al.   JOURNAL OF HEPATOLOGY

Retention of CD4+ CD25+ FoxP3+ Regulatory T Cells in the Liver after Therapy-Induced Hepatitis C Virus Eradication in Humans

(2011) M. A. A. Claassen et al.   JOURNAL OF VIROLOGY

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY