Ursodeoxycholic Acid Suppresses Lipogenesis in Mouse Liver: Possible Role of the Decrease in β-Muricholic Acid, a Farnesoid X Receptor Antagonist

Ursodeoxycholic acid decreases age-related adiposity and inflammation in mice

(2016) Ah-Reum Oh et al.   BMB Reports

Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity

(2015) Michaela Mueller et al.   JOURNAL OF HEPATOLOGY

Cross-talk between bile acids and intestinal microbiota in host metabolism and health

(2015) Yang-fan Nie et al.   Journal of Zhejiang University-SCIENCE B

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

(2015) Changtao Jiang et al.   Nature Communications

Bile acid supplementation improves established liver steatosis in obese mice independently of glucagon-like peptide-1 secretion

(2014) Pablo Quintero et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Dietary Hyodeoxycholic Acid Exerts Hypolipidemic Effects by Reducing Farnesoid X Receptor Antagonist Bile Acids in Mouse Enterohepatic Tissues

(2014) Shiro Watanabe et al.   LIPIDS

Beyond intestinal soap—bile acids in metabolic control

(2014) Folkert Kuipers et al.   Nature Reviews Endocrinology

Human FXR Regulates SHP Expression through Direct Binding to an LRH-1 Binding Site, Independent of an IR-1 and LRH-1

(2014) Martijn O. Hoeke et al.   PLoS One

Ursodeoxycholic Acid Ameliorates Fructose-Induced Metabolic Syndrome in Rats

(2014) Amr A. A. Mahmoud et al.   PLoS One

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Ursodeoxycholic Acid Inhibits Liver X Receptor α-mediated Hepatic Lipogenesis via Induction of the Nuclear Corepressor SMILE

(2013) Ji-Min Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism

(2013) X. Hu et al.   JOURNAL OF INTERNAL MEDICINE

Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

(2012) Juan C. García-Cañaveras et al.   JOURNAL OF LIPID RESEARCH

Ursodeoxycholic acid dose-dependently improves liver injury in rats fed a methionine- and choline-deficient diet

(2011) Vyacheslav U. Buko et al.   HEPATOLOGY RESEARCH

Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet–fed KK-Ay mice

(2011) Takuma Tsuchida et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis

(2010) Tiangang Li et al.   HEPATOLOGY

Effects of farnesoid X receptor on the expression of the fatty acid synthetase and hepatic lipase

(2010) Li-Li Shen et al.   MOLECULAR BIOLOGY REPORTS

Anti-Inflammatory and Proresolving Lipid Mediators

(2008) Charles N. Serhan et al.   Annual Review of Pathology-Mechanisms of Disease