Dysfunction of the WT1-MEG3 signaling promotes AML leukemogenesis via p53-dependent and -independent pathways

Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia

(2016) R. Rampal et al.   HAEMATOLOGICA

MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53

(2016) Magdalena Wienken et al.   MOLECULAR CELL

Evidence from pyrosequencing indicates that natural variation in animal personality is associated with DRD4 DNA methylation

(2016) Eveline C. Verhulst et al.   MOLECULAR ECOLOGY

Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia

(2016) R. Rampal et al.   HAEMATOLOGICA

Long noncoding RNAs in hematopoietic malignancies

(2015) Norma I. Rodríguez-Malavé et al.   Briefings in Functional Genomics

The TET2 interactors and their links to hematological malignancies

(2015) Feng Pan et al.   IUBMB LIFE

Tumor suppression by MEG3 lncRNA in a human pituitary tumor derived cell line

(2015) Paweena Chunharojrith et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

WT1 Recruits TET2 to Regulate Its Target Gene Expression and Suppress Leukemia Cell Proliferation

(2015) Yiping Wang et al.   MOLECULAR CELL

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

Long Noncoding RNA MEG3 Interacts with p53 Protein and Regulates Partial p53 Target Genes in Hepatoma Cells

(2015) Juanjuan Zhu et al.   PLoS One

The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature

(2015) Marina Díaz-Beyá et al.   Oncotarget

Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

(2014) Matthew T. Weirauch et al.   CELL

Long noncoding RNAs during normal and malignant hematopoiesis

(2014) Juan R. Alvarez-Dominguez et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

WT1 mutations are secondary events in AML, show varying frequencies and impact on prognosis between genetic subgroups

(2014) M-T Krauth et al.   LEUKEMIA

An update on LNCipedia: a database for annotated human lncRNA sequences

(2014) Pieter-Jan Volders et al.   NUCLEIC ACIDS RESEARCH

Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression

(2013) Kai-hua Lu et al.   BMC CANCER

Expression, regulation and roles of miR-26a and MEG3 in tongue squamous cell carcinoma

(2013) Ling-Fei Jia et al.   INTERNATIONAL JOURNAL OF CANCER

Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer

(2013) Ming Sun et al.   TUMOR BIOLOGY

MDM2 Overexpression Deregulates the Transcriptional Control of RB/E2F Leading to DNA Methyltransferase 3A Overexpression in Lung Cancer

(2012) Y.-A. Tang et al.   CLINICAL CANCER RESEARCH

Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation

(2012) Pengjun Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics

(2011) W.-C. Chou et al.   BLOOD

DNA Methylation of Intronic Enhancers Directs Tissue-Specific Expression of Steroidogenic Factor 1/Adrenal 4 Binding Protein (SF-1/Ad4BP)

(2011) Erling A. Hoivik et al.   ENDOCRINOLOGY

MEG3 imprinted gene contribution in tumorigenesis

(2011) Leonidas Benetatos et al.   INTERNATIONAL JOURNAL OF CANCER

An upstream insulator regulates DLK1 imprinting in AML

(2010) H. Khoury et al.   BLOOD

Maternally Expressed Gene 3, an Imprinted Noncoding RNA Gene, Is Associated with Meningioma Pathogenesis and Progression

(2010) X. Zhang et al.   CANCER RESEARCH

The IG-DMR and the MEG3-DMR at Human Chromosome 14q32.2: Hierarchical Interaction and Distinct Functional Properties as Imprinting Control Centers

(2010) Masayo Kagami et al.   PLoS Genetics

Maternally Expressed Gene 3 (MEG3) Noncoding Ribonucleic Acid: Isoform Structure, Expression, and Functions

(2009) Xun Zhang et al.   ENDOCRINOLOGY

CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes

(2009) Leonidas Benetatos et al.   LEUKEMIA RESEARCH

Insights from genomic profiling of transcription factors

(2009) Peggy J. Farnham   NATURE REVIEWS GENETICS

Mutation inTET2in Myeloid Cancers

(2009) François Delhommeau et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

(2008) Peter Paschka et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype

(2008) C Haferlach et al.   LEUKEMIA