Differential signaling through p190 and p210 BCR-ABL fusion proteins revealed by interactome and phosphoproteome analysis

First line treatment with newer tyrosine kinase inhibitors in chronic myeloid leukemia associated with deep and durable molecular response – systematic review and meta-analysis

(2016) Ronit Gurion et al.   ACTA ONCOLOGICA

PyQuant: A Versatile Framework for Analysis of Quantitative Mass Spectrometry Data

(2016) Christopher J. Mitchell et al.   MOLECULAR & CELLULAR PROTEOMICS

The Transcription Factor ARID3a Is Important for In Vitro Differentiation of Human Hematopoietic Progenitors

(2015) Michelle L. Ratliff et al.   JOURNAL OF IMMUNOLOGY

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

(2015) Jean-Philippe Lambert et al.   Journal of Proteomics

Phosphorylated SHIP2 on Y1135 localizes at focal adhesions and at the mitotic spindle in cancer cell lines

(2014) Laurence Deneubourg et al.   CELLULAR SIGNALLING

Editorial: Recovery from chemotherapy depends on STAT1 for replenishment of B lymphopoiesis

(2014) Birgit Strobl et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Heterogeneity of Pancreatic Cancer Metastases in a Single Patient Revealed by Quantitative Proteomics

(2014) Min-Sik Kim et al.   MOLECULAR & CELLULAR PROTEOMICS

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Wiskott-Aldrich syndrome: a comprehensive review

(2013) Michel J. Massaad et al.   Annals of the New York Academy of Sciences

A role for RUNX1 in hematopoiesis and myeloid leukemia

(2013) Motoshi Ichikawa et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Diverging fates of cells of origin in acute and chronic leukaemia

(2012) Boris Kovacic et al.   EMBO Molecular Medicine

p210bcr-abl induces amoeboid motility by recruiting ADF/destrin through RhoA/ROCK1

(2012) Tristan Rochelle et al.   FASEB JOURNAL

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression

(2012) I Tala et al.   LEUKEMIA

BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

(2012) Oliver Hantschel et al.   Nature Chemical Biology

High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia

(2011) W. Warsch et al.   BLOOD

Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

(2011) R. Foa et al.   BLOOD

Molecular Pathways: BCR-ABL

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis

(2011) Kentson Lam   Frontiers in Bioscience-Landmark

Global Phosphoproteomics Reveals Crosstalk Between Bcr-Abl and Negative Feedback Mechanisms Controlling Src Signaling

(2011) L. Rubbi et al.   Science Signaling

Stat5 is indispensable for the maintenance ofbcr/abl-positive leukaemia

(2010) Andrea Hoelbl et al.   EMBO Molecular Medicine

Tyrosine phosphorylation of SHIP promotes its proteasomal degradation

(2010) Jens Ruschmann et al.   EXPERIMENTAL HEMATOLOGY

Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate

(2010) Xianwen Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hoxa9 Regulates Flt3 in Lymphohematopoietic Progenitors

(2010) K. Gwin et al.   JOURNAL OF IMMUNOLOGY

Analysis of genomic breakpoints in p190 and p210 BCR–ABL indicate distinct mechanisms of formation

(2010) J Score et al.   LEUKEMIA

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization

(2010) B Titz et al.   ONCOGENE

The function of the pleckstrin homology domain in BCR–ABL-mediated leukemogenesis

(2009) S Demehri et al.   LEUKEMIA

Charting the molecular network of the drug target Bcr-Abl

(2009) M. Brehme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The different functions of Stat5 and chromatin alteration through Stat5 proteins

(2008) Jan-Wilhelm Kornfeld   Frontiers in Bioscience-Landmark

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5

(2008) Jagan M R Pongubala et al.   NATURE IMMUNOLOGY