Article
Surgery
Y. Huang, J. Sanz, N. Rodriguez, P. Foro, A. Reig, I Membrive, M. Zhao, X. Li, A. Martinez, M. Algara
Summary: This study analyzed patients undergoing radiotherapy and breast reconstruction, finding that regardless of timing or techniques, breast reconstruction combined with radiotherapy seemed to be successful, with autologous reconstruction requiring more revision surgeries.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2021)
Review
Surgery
Xiaoshuang Guo, Zhaojian Wang, Ye Wang, Xiaolei Jin
Summary: This meta-analysis investigated the timing of postmastectomy radiotherapy (PMRT) in breast cancer patients undergoing immediate two-stage prosthetic breast reconstruction. The results showed that delivering PMRT to the tissue expander was associated with a lower risk of severe capsular contracture, while delivering PMRT to the permanent implant reduced the risk of implant loss. However, the heterogeneity in statistical methods and definitions should be taken into consideration when interpreting the synthesized result.
INTERNATIONAL JOURNAL OF SURGERY
(2022)
Article
Oncology
Walter Paul Weber, Jane Shaw, Andrea Pusic, Lynda Wyld, Monica Morrow, Tari King, Zoltan Matrai, Joerg Heil, Florian Fitzal, Shelley Potter, Isabel T. Rubio, Maria-Joao Cardoso, Oreste Davide Gentilini, Viviana Galimberti, Virgilio Sacchini, Emiel J. T. Rutgers, John Benson, Tanir M. Allweis, Martin Haug, Regis R. Paulinelli, Tibor Kovacs, Yves Harder, Bahadir M. Gulluoglu, Eduardo Gonzalez, Andree Faridi, Elisabeth Elder, Peter Dubsky, Jens-Uwe Blohmer, Vesna Bjelic-Radisic, Mitchel Barry, Susanne Dieroff Hay, Kimberly Bowles, James French, Roland Reitsamer, Rupert Koller, Peter Schrenk, Daniela Kauer-Dorner, Jorge Biazus, Fabricio Brenelli, Jaime Letzkus, Ramon Saccilotto, Sarianna Joukainen, Susanna Kauhanen, Ulla Karhunen-Enckell, Juergen Hoffmann, Ulrich Kneser, Thorsten Kuhn, Michalis Kontos, Ekaterini Christina Tampaki, Moshe Carmon, Tal Hadar, Giuseppe Catanuto, Carlos A. Garcia-Etienne, Linetta Koppert, Pedro F. Gouveia, Jakob Lagergren, Tor Svensjoe, Nadia Maggi, Elisabeth A. Kappos, Fabienne D. Schwab, Liliana Castrezana, Daniel Steffens, Janna Krol, Christoph Tausch, Andreas Gunthert, Michael Knauer, Maria C. Katapodi, Susanne Bucher, Nik Hauser, Christian Kurzeder, Rosine Mucklow, Pelagia G. Tsoutsou, Atakan Sezer, Guldeniz Karadeniz Cakmak, Hasan Karanlik, Patricia Fairbrother, Laszlo Romics, Giacomo Montagna, Cicero Urban, Melanie Walker, Silvia C. Formenti, Guenther Gruber, Frank Zimmermann, Daniel Rudolf Zwahlen, Sherko Kuemmel, Mahmoud El-Tamer, Marie Jeanne Vrancken Peeters, Orit Kaidar-Person, Michael Gnant, Philip Poortmans, Jana de Boniface
Summary: The aim of this article is to discuss the demand for nipple-and skin-sparing mastectomy (NSM/SSM) with immediate breast reconstruction (BR) and present clinical practice recommendations in the context of expanded indications for post-mastectomy radiation therapy (PMRT). The panel agrees that surgical technique for NSM/SSM should not be modified when PMRT is planned, with preference for autologous over implant-based BR. However, no specific recommendations are made regarding implant positioning, use of mesh or timing. The use of patient-reported outcomes in clinical practice is endorsed. The article emphasizes the importance of prospective randomized phase III studies and interdisciplinary collaboration for determining optimal sequencing and techniques for PMRT in the context of BR.
Review
Surgery
Yanxin Ren, Yan Yu, Kexin Xu, Zhoujian Li, Xiao Wang
Summary: This meta-analysis compared the incidence of complications and patient-reported outcomes between immediate autologous breast reconstruction (ABR) and immediate implant-based breast reconstruction (IBBR) in breast cancer patients undergoing postmastectomy radiotherapy. The results showed that IBBR had a lower risk of reconstruction failure compared to ABR, while the risk for complications requiring reoperation did not significantly differ between the two groups. However, due to variations in statistical definitions and methodologies, the synthesized result should be critically interpreted. More high-quality studies are needed for further refinement of clinical practice.
AESTHETIC PLASTIC SURGERY
(2023)
Article
Oncology
Sarah Giunta, Rebekah Laidsaar-Powell, Lorna Huang, Natasha Hatcher, Haryana Dhillon, Danielle M. Muscat, Susan Carroll, Catriona McNeil, Lucinda Burke, Pamela Howson, Belinda Chan, Ilona Juraskova
Summary: The study reveals that Australian women's decisions about breast reconstruction are influenced by factors such as information provision, values and preferences, social influence, etc. Breast care nurse support and collaboration and communication within multidisciplinary teams play a crucial role in assisting women in making decisions.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2021)
Article
Oncology
J. P. M. O'Donnell, D. Murphy, E. J. Ryan, S. A. Gasior, R. Sugrue, B. Lane O'Neill, M. R. Boland, A. J. Lowery, M. J. Kerin, N. M. McInerney
Summary: The optimal approach to avoid reconstructive failure in breast cancer patients is found to be autologous flap reconstruction combined with PMRT, while implant-based reconstruction performed prior to PMRT can reduce complication rates.
Article
Oncology
Sara R. Alcorn, Jean L. Wright
Summary: This study demonstrates that adjuvant trastuzumab-emtansine (T-DM1) improves invasive disease-free survival in patients with nonmetastatic HER2-positive breast cancer who have residual invasive disease after preoperative chemotherapy plus trastuzumab. Adjuvant T-DM1 is now recommended for these patients, requiring concurrent radiation therapy.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2022)
Article
Oncology
Dong-Yun Kim, Eonju Park, Chan Yeong Heo, Ung Sik Jin, Eun Kyu Kim, Wonshik Han, Kyung Hwan Shin, In Ah Kim
Summary: The study found that there was no significant difference in breast-related complications between hypofractionated and conventional fractionated adjuvant radiotherapy in reconstructed breast cancer patients. Hypofractionated radiotherapy showed a significant advantage in reducing major contracture compared to conventional radiotherapy.
Article
Surgery
Ara Kim, Juyoung Bae, Sa-Ik Bang, Jai-Kyong Pyon
Summary: The timing of expander-to-implant exchange after radiation therapy has different effects on short-term and long-term complications. The optimal time point for permanent implant placement is 131 days after radiation therapy, reducing short-term complications significantly but not long-term complications.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Review
Oncology
Iveta Kolarova, Bohuslav Melichar, Jaroslav Vanasek, Igor Sirak, Jiri Petera, Katerina Horackova, Denisa Pohankova, Zuzana Sinkorova, Oldrich Hosek, Milan Vosmik
Summary: Radiotherapy plays a crucial role in the treatment of breast cancer, with modern techniques allowing for better target coverage and shorter treatment times. However, there are challenges with adjuvant radiotherapy immediately after breast replacement surgery. Newer techniques minimize radiation to healthy tissue, reducing adverse effects and recovery times. External beam partial breast irradiation is currently supported for selected patients.
Article
Oncology
Andrei Ludovic Porosnicu, Stefania Mihaela Riza, Ioana Antonia Stanculescu, Sorin Viorel Parasca, Cristian Radu Jecan, Ruxandra Diana Sinescu
Summary: In breast cancer patients, immediate breast reconstruction after radical mastectomy is a common practice nowadays due to improved diagnostic tools. However, the reconstruction possibilities become a subject of debate in the presence of postmastectomy radiotherapy (PMRT) because of the increased risk of complications. This study aimed to evaluate the effects of radiotherapy on the outcome and costs of delayed two-stage breast reconstruction in a cohort of patients in Bucharest, Romania.
Article
Surgery
Jana de Boniface, Robert Szulkin, Anna L. Johansson
Summary: Older women with breast cancer have a higher risk of major medical complications after surgery, especially those who undergo mastectomy. The removal of the whole breast is associated with a higher risk of complications and worse survival in older patients. Mastectomy should be considered with caution in older women.
BRITISH JOURNAL OF SURGERY
(2023)
Article
Medicine, General & Internal
Jeongshin An, Hyungju Kwon, Woosung Lim, Byung-In Moon, Nam Sun Paik
Summary: The study introduces the use of ADM in breast reconstruction during BCS, targeting patients with minor to severe defects post-operation. Results show that ADM can quickly correct breast shape after conventional BCS surgery, with pellet-type ADM creating a breast shape similar to pre-surgery. Despite the longer surgical time, the use of ADM in breast reconstruction proves to be effective in improving shape with minor complications.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Oncology
Koichi Tomita, Tateki Kubo
Summary: Although the number of breast cancer patients continues to rise, the survival rates have improved, leading to longer lives for survivors. Breast reconstruction plays a vital role in improving quality of life after breast cancer surgery. Advances in techniques such as silicone gel implants, autologous tissue transfer, tissue expanders, perforator flaps, and fat grafting have made the procedure less invasive and more versatile. This review gives an overview of recent advancements in breast reconstruction techniques.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Chiu-Ping Chen, Chi-Yeh Lin, Chia-Chun Kuo, Tung-Ho Chen, Shao-Chen Lin, Kuo-Hsiung Tseng, Hao-Wen Cheng, Hsing-Lung Chao, Sang-Hue Yen, Ruo-Yu Lin, Chen-Ju Feng, Long-Sheng Lu, Jeng-Fong Chiou, Shih-Ming Hsu
Summary: Breast immobilization with personalized breast holder (PERSBRA) is a promising approach for reducing toxicity in the lungs and heart during whole breast radiotherapy. This study evaluated the skin surface dose for breast radiotherapy with PERSBRA using different radiotherapy techniques.