Review
Immunology
Altijana Hromic-Jahjefendic, Debmalya Barh, Vladimir Uversky, Alaa A. Aljabali, Murtaza M. Tambuwala, Khalid J. Alzahrani, Fuad M. Alzahrani, Saleh Alshammeri, Kenneth Lundstrom
Summary: According to the WHO, there have been more than 850 million cases and over 6.6 million deaths from COVID-19 worldwide as of January 2023. The reduced death rates are primarily due to the decreased pathogenicity of new SARS-CoV-2 variants and the administration of over 12.8 billion vaccine doses globally. While some serious side effects have been reported after COVID-19 vaccinations, they are relatively low in number. It is important for the scientific community to thoroughly investigate the complications caused by COVID-19 vaccines and take necessary safety measures.
Article
Health Care Sciences & Services
Hang Dong, Matus Falis, William Whiteley, Beatrice Alex, Joshua Matterson, Shaoxiong Ji, Jiaoyan Chen, Honghan Wu
Summary: Clinical coding is the process of transforming medical information into structured codes for statistical analysis. Automated clinical coding is a promising task for AI, but there are challenges in achieving explainability and consistency. Involvement of coders is necessary in the development process.
NPJ DIGITAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Aviva Philipp-Muller, Spike W. S. Lee, Richard E. Petty
Summary: This article explores the psychology behind antiscience attitudes and identifies four core principles driving these attitudes. It highlights the importance of source credibility, social identity, information processing, and message delivery in shaping antiscience attitudes. Politics plays a crucial role in triggering or amplifying these principles, making it a potent force. Evidence-based counteractive strategies are provided for increasing public acceptance of science.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Review
Biochemistry & Molecular Biology
Izabela Kolodziejczyk, Przemyslaw Tomczyk, Andrzej Kazmierczak
Summary: In recent years, new insights into a cell replication process known as endoreplication, which is common in plants and accompanies changes in animal development, have emerged. This paper aims to shed light on this phenomenon and promote understanding of its potential applications in plant cultivation. Endoreplication differs from the classical somatic cell cycle and is a compensation for the relatively small amount of genetic material in plants. It allows for the multiplication and active use of genetic material, resulting in desirable features such as vibrant colors, aroma, taste, nutrient accumulation, stress resistance, tolerance to adverse conditions, and faster organ growth in plants. The article also discusses practical applications and limitations of endoreplication.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Inorganic & Nuclear
Mariola Koszytkowska-Stawinska, Wlodzimierz Buchowicz
Summary: The bioorganometallic chemistry of ferrocene is increasingly important, as demonstrated by the significant biological properties of ferrocene-triazole conjugates. These conjugates are synthesized via azide-alkyne cycloaddition reactions and have been shown to exhibit various activities such as anticancer, antibacterial and/or antifungal, antiprotozoal, and other effects. The role of the ferrocene core in the biological activity of these conjugates is still not fully understood, but the redox properties of ferrocene have been proposed to be important in some cases.
DALTON TRANSACTIONS
(2023)
Article
Astronomy & Astrophysics
Stijn N. B. Debackere, Henk Hoekstra, Joop Schaye, Katrin Heitmann, Salman Habib
Summary: The study shows that the abundance of galaxy clusters is highly sensitive to the late-time evolution of matter distribution. It suggests that projected aperture masses are better for cluster cosmology as they can be measured more precisely and are not affected by assumptions about density profiles.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2022)
News Item
Multidisciplinary Sciences
Dyani Lewis
Summary: The coronavirus can linger on surfaces, but they are not a major source of infection.
Review
Neurosciences
Francesca Malerba
Summary: In 2007, Rita Levi-Montalcini proposed a new project and formed a research group at the European Brain Research Institute. As a young researcher, I had the opportunity to work with her and learn from her approach and attitude. She taught me to be open-minded, rational, and optimistic in my scientific pursuits. Her example has provided me with a reliable path to follow and continues to inspire me.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Adriaan Barbaroux, Isabelle Pourrat, Tiphanie Bouchez
Summary: French general practitioners have an unfavorable opinion of the pharmaceutical industry, but their behavior towards sales representatives is generally positive. This study explores the reasons behind this discrepancy and reveals practical, social, and psychological motivations that lead GPs to continue meeting with sales reps.
Review
Biodiversity Conservation
Maurizio Rossetto, Robert Kooyman
Summary: Refugia play a crucial role in protecting biodiversity by buffering environmental conditions. Improved understanding of what is being protected by refugia and why is essential for critical decision-making in biological conservation. Definitions of persistent, future, and temporary refugia, along with identification, core value, and management strategy criteria, can assist decision-making for short- and long-term conservation goals.
Article
Immunology
Elaine Kouame, Justine C. Noel, Madina Wane, Joel Babdor, Heather L. Caslin, Amy Fan, Berenice Mbiribindi, Susanne Sattler, Alexis S. Mobley
Summary: The organization Black in Immuno was formed to celebrate and support Black voices in immunology, culminating in the global event Black in Immuno Week, which aimed to highlight Black excellence, advocate for diversity in immunology, and create a supportive community for Black immunologists.
JOURNAL OF IMMUNOLOGY
(2021)
Review
Oncology
Alessandro Di Federico, Mirta Mosca, Rachele Pagani, Riccardo Carloni, Giorgio Frega, Andrea De Giglio, Alessandro Rizzo, Dalia Ricci, Simona Tavolari, Mariacristina Di Marco, Andrea Palloni, Giovanni Brandi
Summary: Immunotherapy and targeted therapies have not been as successful in treating pancreatic cancer as they have in other malignancies, possibly due to the unique tumor microenvironment of pancreatic cancer. This review provides a comprehensive overview of the distinctive tumor immune microenvironment of pancreatic cancer and summarizes existing data on the use of immunotherapy and immune biomarkers in this cancer.
Article
Health Care Sciences & Services
Mathias Akugizibwe, Flavia Zalwango, Chaka Moreen Namulundu, Ivan Namakoola, Josephine Birungi, Joseph Okebe, Max Bachmann, Murdoch Jamie, Shabbar Jaffar, Marie Claire Van Hout
Summary: This study explores the impact of integrating HIV, diabetes, and hypertension care on HIV stigma dynamics in Uganda. It finds that integrated care reduces healthcare visits, costs, and stigma, improves patient-provider relationships, and enhances healthcare providers' capacity to manage multiple chronic conditions. However, challenges at the service level and societal discrimination among HIV patients remain.
BMC HEALTH SERVICES RESEARCH
(2023)
Editorial Material
Cell Biology
Audrey Penning, Jana Jeschke, Francois Fuks
Summary: The paper discusses the challenges in studying novel mRNA modifications and provides insights on how to overcome them.
NATURE REVIEWS MOLECULAR CELL BIOLOGY
(2022)
Article
Psychology, Developmental
Patrick L. Hill, Anthony L. Burrow
Summary: This article discusses whether youth have purpose, emphasizing the importance of a sense of purpose and arguing that adolescents generally perceive themselves to have a purpose, providing a more inclusive and positive portrayal of young people.
CHILD DEVELOPMENT PERSPECTIVES
(2021)
