Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation

(2016) Christopher J. Tape et al.   CELL

Combination gemcitabine/cisplatin therapy and ERCC1 expression for resected pancreatic adenocarcinoma: Results of a Phase II prospective trial

(2016) Lauren M. Postlewait et al.   JOURNAL OF SURGICAL ONCOLOGY

Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells

(2016) Michael Friberg Bruun Nielsen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling

(2015) I. Roy et al.   CANCER RESEARCH

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma

(2014) Andrew D. Rhim et al.   CANCER CELL

Phase I Dose-Escalation Trial of the Oral Investigational Hedgehog Signaling Pathway Inhibitor TAK-441 in Patients with Advanced Solid Tumors

(2014) J. Goldman et al.   CLINICAL CANCER RESEARCH

Pilot Clinical Trial of Hedgehog Pathway Inhibitor GDC-0449 (Vismodegib) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma

(2014) E. J. Kim et al.   CLINICAL CANCER RESEARCH

CXCL12 Chemokine Expression Suppresses Human Pancreatic Cancer Growth and Metastasis

(2014) Ishan Roy et al.   PLoS One

Chemokines and chemokine receptors: Update on utility and challenges for the clinician

(2014) Ishan Roy et al.   SURGERY

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

Pancreatic stellate cells: a starring role in normal and diseased pancreas

(2012) Minoti V. Apte et al.   Frontiers in Physiology

Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy

(2011) R. Rezakhaniha et al.   Biomechanics and Modeling in Mechanobiology

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

(2011) Hyung-Ok Lee et al.   BMC CANCER

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

(2011) Hideaki Ijichi et al.   JOURNAL OF CLINICAL INVESTIGATION

Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma

(2011) Daniel Baumhoer et al.   MODERN PATHOLOGY

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells

(2011) Andrea Facciabene et al.   NATURE

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer

(2010) Edneia AS Ramos et al.   BMC CANCER

Pancreatic cancer associated fibroblasts display normal allelotypes

(2010) Kimberly Walter et al.   CANCER BIOLOGY & THERAPY

Pancreatic Stellate Cells Increase the Invasion of Human Pancreatic Cancer Cells through the Stromal Cell-Derived Factor-1/CXCR4 Axis

(2010) Zhenjun Gao et al.   PANCREATOLOGY

Isoform-Specific Upregulation of Palladin in Human and Murine Pancreas Tumors

(2010) Silvia M. Goicoechea et al.   PLoS One

Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice

(2009) Michael P Kim et al.   Nature Protocols

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

(2008) Atsushi Masamune et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer

(2008) J. M. Bailey et al.   CLINICAL CANCER RESEARCH

Fibrinogen induces cytokine and collagen production in pancreatic stellate cells

(2008) A Masamune et al.   GUT