Journal
LAB ON A CHIP
Volume 17, Issue 4, Pages 635-639Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7lc00079k
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Funding
- NIH [HL109442, AI096305, GM110494]
- Guangdong Innovative and Entrepreneurial Research Team Program [2013S086]
- Global Research Laboratory Program (Korean NSF GRL) [2015032163]
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To advance emulsion droplet technology, we synthesize functional derivatives of Pluronic F127 that can simultaneously act as surfactants and as reactive sites for droplet surface decoration. The amine-, carboxyl-, N-hydroxysuccinimide ester-, maleimide- and biotin-terminated Pluronic F127 allows ligand immobilization on single-emulsion or double-emulsion droplets via electrostatic adsorption, covalent conjugation or site-specific avidin-biotin interaction.
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