Article
Orthopedics
Anthony G. Schache, Prasanna Sritharan, Adam G. Culvenor, Brooke E. Patterson, Luke G. Perraton, Adam L. Bryant, Ali Guermazi, Hayden G. Morris, Timothy S. Whitehead, Kay M. Crossley
Summary: Patellofemoral joint (PFJ) osteoarthritis is common following anterior cruciate ligament reconstruction (ACLR) and altered joint loading may contribute. This study examined the relationship between PFJ loading and prevalent and worsening PFJ osteoarthritis post-ACLR. The results showed that lower peak PFJ contact force was associated with prevalent early PFJ osteoarthritis at 1-year post-ACLR and a higher risk of worsening PFJ osteoarthritis between 1- and 5-years post-ACLR.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Article
Orthopedics
Argell J. San Jose, Nirav Maniar, Rodney Whiteley, David A. Opar, Ryan G. Timmins, Roula Kotsifaki
Summary: After ACL reconstruction, there is a lower patellofemoral joint contact force and deficits in quadriceps force and knee flexion angle during side-step cutting tasks. This indicates an increased risk of developing patellofemoral osteoarthritis even after ACL reconstruction.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2023)
Article
Multidisciplinary Sciences
Raelene M. Cowie, Philippa Bowland, Divya Baji, Hazel L. Fermor, Eileen Ingham, John Fisher, Louise M. Jennings
Summary: This study developed a method to simulate physiological loading and motion in the porcine patellofemoral joint using a 6-axis simulator, and investigated the influence of surgical positioning of osteochondral allografts in the patella. Allografts implanted flush with the surrounding cartilage could restore the articulating surface of the patella resulting in low wear, damage and deformation of the opposing cartilage surface.
Article
Orthopedics
Ke Song, Rodrigo Scattone Silva, Todd J. Hullfish, Karin Gravare Silbernagel, Josh R. Baxter
Summary: This study defines a loading index to quantify patellofemoral joint loading in various weightbearing exercises and activities. The results show that most rehabilitation exercises generate a moderate level of loading, with few exercises resembling walking or providing high-level loading. Exercises with high knee flexion tend to have higher patellofemoral joint loading.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2023)
Article
Rehabilitation
Danielle Goulette, Patrick Griffith, Michael Schiller, Drew Rutherford, Thomas W. Kernozek
Summary: This study aimed to examine the effects of two lunge movements on patellofemoral joint loading, with results indicating that the Forward Lunge produced greater PFJ loading variables compared to the Backward Lunge. Further research is needed to explore the impact on individuals with patellofemoral pain (PFP) when using the Backward Lunge.
PHYSICAL THERAPY IN SPORT
(2021)
Article
Chemistry, Analytical
Robert Karpinski, Przemyslaw Krakowski, Jozef Jonak, Anna Machrowska, Marcin Maciejewski, Adam Nogalski
Summary: This study evaluated the examination and acquisition protocol for the patellofemoral joint using vibroarthrography (VAG) and determined the optimal protocol for diagnostic results. Neural networks were used for classification, suggesting the potential for simplifying the examination protocol to single kinetic chain analyses.
Article
Ecology
Peter J. Bishop, Robert J. Brocklehurst, Stephanie E. Pierce
Summary: This study introduces an iterative algorithm called 'APSE' for quantifying joint function and mobility, which can rapidly and intelligently sample high-dimensional joint pose space. The algorithm produces high-dimensional joint mobility assessments with greater precision and significantly reduces the computational time required for analysis.
METHODS IN ECOLOGY AND EVOLUTION
(2023)
Article
Multidisciplinary Sciences
Stanislaw Burzynski, Agnieszka Sabik, Wojciech Witkowski, Piotr Luczkiewicz
Summary: Soft tissue tension is an important factor in post-THA dislocation, with femoral offset playing a significant role in stabilizing the prosthesis. This study found that an increased femoral offset can stretch the quadratus femoris muscle significantly, enhancing its stabilizing effect on the hip prosthesis.
Article
Orthopedics
Heath P. Gould, Nicholas R. Delaney, Brent G. Parks, Roshan T. Melvani, Richard Y. Hinton
Summary: This study aimed to compare suture anchors (SAs) with interference screws (IS) for femoral fixation in medial patellofemoral ligament (MPFL) reconstruction. The results showed no significant difference in load to failure, but interference screws had significantly higher mean stiffness compared to suture anchors.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2021)
Article
Biotechnology & Applied Microbiology
Liang Chen, Ziang Jiang, Chen Yang, Rongshan Cheng, Size Zheng, Jingguang Qian
Summary: The study found that different landing actions have impact on muscle forces and knee joint angles, but not significantly on ACL forces. Factors like knee flexion angle and quadriceps and gastrocnemius forces are critical for ACL injury.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
Xijin Hua, Junyan Li, Enrico De Pieri, Stephen J. Ferguson
Summary: This study developed a multiscale computational modeling approach to investigate the time-dependent biphasic behavior of the articular cartilage in the hip joint under physiological loading. The results showed that the interstitial fluid pressure in the cartilage supported the majority of the load, and the location of the contact area affected the changes in peak pressures during various activities.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Review
Medicine, Research & Experimental
Maria Justina Roxana Virlan, Diana Loreta Paun, Elena Nicoleta Bordea, Angelo Pellegrini, Arsenie Dan Spinu, Roxana Victoria Ivascu, Victor Nimigean, Vanda Roxana Nimigean
Summary: This study assessed significant factors influencing the inclination of the AE, especially modifications caused by aging, biological sex or edentulism. The research found that various factors have an impact on the angle of the AE, with edentulism being a significant factor.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2021)
Review
Materials Science, Multidisciplinary
Nian Liu, Huabo Zhang, Xingyu Ni, Tiancheng Liu, Nan Jiang
Summary: This review compares the similarities and differences between condylar cartilage and tibial plateau cartilage in terms of composition, structure, biomechanics, and tissue-engineering strategies. The researches included in this review concluded the focus and deficiency of the studies. The two cartilages are roughly divided into four layers in structure, but there are differences in cell shape and size as well as the way collagen exists. The tibial cartilage has stronger compression resistance compared to the condylar cartilage, which is related to their roles in normal life.
ADVANCED ENGINEERING MATERIALS
(2022)
Article
Orthopedics
Wenhan Huang, Xiaolong Zeng, Gene Chi-Wai Man, Liu Yang, Yu Zhang
Summary: The aim of this study was to measure the kinematics and contact pressures in cadaveric knees. High ICC values were found for 6 degrees of freedom in the patellofemoral joints. There were no significant differences in PFJ kinematics with and without the pressure sensor, and most ICC values for contact pressures ranged from 0.8 to 0.9, allowing for accurate interpretation of the measurements.
ORTHOPAEDIC SURGERY
(2022)
Article
Biophysics
Chaochao Zhou, Zhenming Zhang, Zhitao Rao, Timothy Foster, Hany Bedair, Guoan Li
Summary: This study compared the morphological and physiological kinematic measures of knee joints during a single-leg lunge, finding differences between the morphological femoral condyle motion and physiological tibiofemoral cartilage contact location changes. The data highlighted the importance of including both morphological and physiological kinematics data in biomechanical evaluations of knee joint motion to accurately demonstrate its functionality.
JOURNAL OF BIOMECHANICS
(2021)
Article
Orthopedics
Merrill Lee, Jade Pei Yuik Ho, Jerry Yongqiang Chen, Chung Kia Ng, Seng Jin Yeo, Azhar M. Merican
Summary: In this study, a reliable method for restoring the anatomical joint line and posterior condylar offset in revision total knee arthroplasty (rTKA) was determined based on three-dimensional reconstruction of computed tomography (CT) images of the distal femur. The findings suggest that fixed ratios of MEPC to TEW (0.33) and MEPC to MEDC (1.06) provide a reliable means for surgeons to determine the anatomical joint line.
JOURNAL OF KNEE SURGERY
(2022)
Article
Orthopedics
Oliver Dandridge, Amy Garner, Andrew A. Amis, Justin P. Cobb, Richard J. van Arkel
Summary: The mechanical advantage of the knee extensor mechanism is heavily influenced by the patellar tendon moment arm (PTMA), which varies due to factors such as gender and knee size. This study optimized PTMA measurement and found that males have a consistently larger PTMA compared to females, with knee size also playing a significant role. The peak PTMA occurs closer to terminal extension in females, despite scaling eliminating sex differences in PTMA magnitude.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Critical Care Medicine
Muhammad Hafiz Hashim, Seow Hui Teo, Mohamed Zubair Mohamed Al-Fayyadh, Sahrinanah Mappiare, Wuey Min Ng, Mohamed Razif Mohamed Ali
Summary: This study compared the strength of Achilles tendons repaired with Giftbox and Krackow techniques after six weeks of healing in rabbits. The results showed that the tendons repaired with the Giftbox technique were significantly stronger biomechanically than those repaired with the Krackow technique.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Article
Orthopedics
K. C. Geoffrey Ng, Marcus J. K. Bankes, Hadi El Daou, Paul E. Beaule, Justin P. Cobb, Jonathan R. T. Jeffers
Summary: This study examined the effects of PAO on capsular mechanics and joint range of motion in dysplastic hips. The results showed that PAO reduced internal rotation and increased external rotation and adduction in the hip joint.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Article
Cell & Tissue Engineering
A. J. Garner, O. W. Dandridge, A. A. Amis, J. P. Cobb, R. J. van Arkel
Summary: The study found that patients who underwent Bi-unicondylar arthroplasty (Bi-UKA) walked faster, had vertical ground reaction forces closer to normal, and longer step lengths compared to matched total knee arthroplasty (TKA) patients. Additionally, Bi-UKA patients reported higher clinical scores and quality of life assessments.
BONE & JOINT RESEARCH
(2021)
Article
Cell & Tissue Engineering
M. J. Munford, J. C. Stoddart, A. D. Liddle, J. P. Cobb, J. R. T. Jeffers
Summary: This study investigates whether titanium lattice implants can maintain natural load transfer in the proximal tibia during UKA and TKA procedures. The results show that titanium lattice implants were able to restore the mechanical environment of the native tibia, while conventional solid implants did not.
BONE & JOINT RESEARCH
(2022)
Article
Cell & Tissue Engineering
T. C. Edwards, B. Guest, A. Garner, K. Logishetty, A. D. Piddle, J. P. Cobb
Summary: This study investigates the use of the metabolic equivalent of task (MET) score in a young hip arthroplasty population and demonstrates its ability to capture additional benefits beyond the ceiling effect of conventional patient-reported outcome measures. The MET is normally distributed in patients following hip arthroplasty, recording levels of activity that are undetectable using the OHS.
BONE & JOINT RESEARCH
(2022)
Review
Cell & Tissue Engineering
Tuan-Xin Goh, Sik-Loo Tan, Margaret M. Roebuck, Seow-Hui Teo, Tunku Kamarul
Summary: This review investigated the expression profiles of EV-derived piRNA in various human samples and their roles in diseases. Differentially expressed EV-piRNAs were found in patients with specific diseases, indicating a potential association between piRNA and disease progression.
TISSUE ENGINEERING PART C-METHODS
(2022)
Article
Cell & Tissue Engineering
J. C. Stoddart, A. Garner, M. Tuncer, J. P. Cobb, R. J. van Arkel
Summary: The study aimed to compare the risk of tibial eminence avulsion intraoperatively for bi-unicondylar knee arthroplasty (Bi-UKA), isolated medial unicondylar knee arthroplasty (UKA-M), and bicruciate-retaining total knee arthroplasty (BCR-TKA) and consider the impact of implant positioning, overstuffing, and sex. The results showed that lateral translation of the medial implant in Bi-UKA and joint overstuffing had the greatest impact on risk increase. Smaller and less dense tibiae had a higher risk, and removing anterior bone doubled the risk.
BONE & JOINT RESEARCH
(2022)
Article
Orthopedics
Sugesh Raghavan, Seow Hui Teo, Mohamed Zubair Mohamed Al-Fayyadh, Mohamed Razif Mohamed Ali, Wuey Min Ng
Summary: This study investigated the presence and quantitative anatomy of the Kaplan fibers in Caucasian and Asian knees. The results showed that the Kaplan fibers are a consistent attachment of the iliotibial band at the distal femur in both groups, with two different patterns of insertion. This information is important for anatomical-based surgical reconstruction.
Article
Medicine, General & Internal
Nik Syazana Izyan Saffery, Krishnamurithy Genasan, Chee Ken Chan, Khairul Anwar Ayob, Seow Hui Teo, Mohamed Zubair Mohamed Al-Fayyadh, Iekhsan Othman, Syafiq Asnawi Zainal Abidin, Murali Malliga Raman, Hanumantha Rao Balaji Raghavendran, Tunku Kamarul
Summary: This study found that osteoarthritis synovium has a specific protein profile that can cause migration, activation, and functional commitment of monocytes. These findings may have important implications for the treatment of osteoarthritis.
FRONTIERS IN MEDICINE
(2022)
Article
Orthopedics
Seow Hui Teo, Teng Khiam Ong, Azhar Mahmood Merican, Muhammad Sufian Hashim, Wuey Min Ng, Mohamed Zubair Mohamed Al-Fayyadh, Mohamed Razif Mohamed Ali
Summary: This study compared the reliabilities between two-dimensional (2-D) and three-dimensional (3-D) methods of measuring TT-TG distance and found that there were no significant differences between the two methods.
INDIAN JOURNAL OF ORTHOPAEDICS
(2023)
Article
Biotechnology & Applied Microbiology
M. Abdulhadi Alagha, Kartik Logishetty, Ciaran O'Hanlon, Alexander D. Liddle, Justin Cobb
Summary: Three-dimensional planning of hip arthroplasty using the 3D Hip Planner software can improve visualization of anatomical landmarks, enhance preoperative implant sizing, and lead to a decrease in surgical time and complications. The study found that the software is valid and reliable, with significant potential in optimizing the quality and accuracy of surgical planning for hip resurfacing arthroplasty.
BIOENGINEERING-BASEL
(2023)
Article
Medicine, General & Internal
Mohamed Zaim Mohamed Thajudeen, Azhar Mahmood Merican, Muhammad Sufian Hashim, Abid Nordin
Summary: Femoral anteversion is an important parameter in total hip arthroplasty, and assessing it can be challenging in cases with significant femoral neck defect. This study found a negative correlation between linea aspera version and femoral anteversion, suggesting that linea aspera can be used as an additional bony landmark for assessing proper implant positioning.
Article
Surgery
Mohamed Zaim bin Mohamed Thajudeen, Azhar Mahmood Merican, Muhammad Sufian Hashim, Abid Nordin
Summary: This study aimed to determine the correlation between femoral anteversion and lesser trochanter version, and the results showed an inverse correlation between them.
SURGICAL TECHNIQUES DEVELOPMENT
(2022)
Article
Orthopedics
Jack Zhong, Nathan J. Lee, Ajay Padaki, Connor Crutchfield, Christopher S. Ahmad, David Trofa, Sean Lynch
Summary: This study aimed to evaluate if age is associated with the risk of short-term complications after ACL reconstruction. The results showed that older patients had higher fragility index scores, shorter operative times, and lower use of general anesthesia. Older age was an independent risk factor for VTE, while younger age was associated with prolonged surgeries.
Article
Orthopedics
Ignacio Pasqualini, Michael Mariorenzi, Alison K. Klika, Pedro J. Rullan, Chao Zhang, Trevor G. Murray, Robert M. Molloy, Nicolas S. Piuzzi
Summary: This study aimed to determine the minimal clinically important difference (MCID) and the patient acceptable symptoms state (PASS) threshold for the knee injury and osteoarthritis outcome score (KOOS) pain subscore, KOOS physical short form (PS), and KOOS joint replacement (JR) following medial unicompartmental knee arthroplasty (mUKA). The study identified useful values for the MCID and PASS thresholds at 1 year following medial UKA of KOOS pain, KOOS PS, and KOOS JR scores. These values may be used as targets for surgeons when evaluating PROMS using KOOS to determine whether patients have achieved successful outcomes after their surgical intervention.