Journal
KIDNEY INTERNATIONAL
Volume 91, Issue 5, Pages 1047-1056Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.kint.2016.10.045
Keywords
acute rejection; chronic kidney disease; kidney transplantation; outcomes; pregnancy
Categories
Funding
- National Institute for Health Research [CL-2015-21-007] Funding Source: researchfish
Ask authors/readers for more resources
Chronic kidney disease (CKD) affects up to 6% of women of childbearing age in high income countries, and is estimated to affect 3% of pregnant women. Advanced renal dysfunction, proteinuria, hypertension, and poorly controlled underlying primary renal disease are all significant risks for adverse maternal, fetal, and renal outcomes. In order to achieve the best outcomes, it is therefore of paramount importance that these pregnancies are planned, where possible, to allow the opportunity to counsel women and their partners in advance and to optimize these risks. These pregnancies should be deemed high risk and they require close antenatal monitoring from an expert multidisciplinary team. We discuss the effect of pregnancy on CKD, and also current guidelines and literature with specific reference to transplantation, autoimmune disease, and medication use in pregnancy. We also discuss the benefits of prepregnancy counseling and give practical recommendations to advise pregnant women with renal disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available