Article
Psychology, Multidisciplinary
Luis-Joaquin Garcia-Lopez, David Jimenez-Vazquez, Jose-Antonio Muela-Martinez, Jose A. Piqueras, Lourdes Espinosa-Fernandez, Josefa Canals-Sans, Manuel Vivas-Fernandez, Paula Morales-Hidalgo, Maria-Mar Diaz-Castela, Maria Rivera, Jill Ehrenreich-May
Summary: This study is the first randomized controlled trial to assess the effectiveness of an online, 8-session group version of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents. The results showed that participants in the intervention group demonstrated improvements in several outcome measures, including reduction of anxiety and mood symptomatology, increase of psychological flexibility, and emotional regulation. Significant differences were found between the intervention group and the control group after the booster session.
CURRENT PSYCHOLOGY
(2023)
Article
Psychiatry
M. J. C. Formica, L. J. Phillips, J. A. Hartmann, A. R. Yung, S. J. Wood, A. Lin, G. P. Amminger, P. D. McGorry, B. Nelson
Summary: The study found that changes in standard treatment, particularly increases in cognitive behavioral therapy (CBT), may have contributed to the decline in psychosis risk observed in recent ultra-high-risk cohorts. However, these variables do not fully explain this trend.
SCHIZOPHRENIA RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Petr Bob, Tereza Petraskova Touskova, Ondrej Pec, Jiri Raboch, Nash Boutros, Paul Lysaker
Summary: This study found a significant correlation between hair cortisol levels and stress symptoms as well as complex partial seizure-like symptoms in patients experiencing their initial episode of psychosis. However, there was no significant correlation between hair cortisol levels and symptoms of anxiety and depression. These findings suggest a potential relationship between epileptic-like symptoms and stress responses in patients during their first psychotic episode.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Psychology, Clinical
Cristina Mei, Mark van der Gaag, Barnaby Nelson, Filip Smit, Hok Pan Yuen, Maximus Berger, Marija Krcmar, Paul French, G. Paul Amminger, Andreas Bechdolf, Pim Cuijpers, Alison R. Yung, Patrick D. McGorry
Summary: Intervention at the earliest illness stage, particularly with cognitive behavioral therapy (CBT), shows promising results in reducing transition rate and attenuating positive psychotic symptoms. However, further research is needed to target other symptom domains and functional outcomes for psychosis prevention.
CLINICAL PSYCHOLOGY REVIEW
(2021)
Article
Psychiatry
Melanie Iorio, Erica Casini, Stefano Damiani, Paolo Fusar-Poli, Renato Borgatti, Martina Maria Mensi
Summary: This study compares family functioning and perceived stress in parents of adolescents with CHR-P, EOP, or other psychiatric disorders. The results suggest that family functioning has a central role in CHR-P adolescents and could be a worthwhile target for intervention.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Psychiatry
Giacomo Ciocca, Tommaso B. Jannini, Michele Ribolsi, Rodolfo Rossi, Cinzia Niolu, Alberto Siracusano, Emmanuele A. Jannini, Giorgio Di Lorenzo
Summary: A considerable amount of literature indicates that individuals with psychotic disorders often experience sexual dysfunctions, possibly due to long-term use of antipsychotic drugs. Research focusing on sexuality in ultra-high risk and first-episode psychosis reveals the impact of sexual dysfunctions during the transition period of illness.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Daan Jan Kuis, Tara van de Giessen, Steven de Jong, Bouwina Esther Sportel, Nynke Boonstra, Rozanne van Donkersgoed, Paul H. Lysaker, Ilanit Hasson-Ohayon, Gerdina Hendrika Maria Pijnenborg
Summary: In individuals in the UHR phase of psychosis, impairments in subjective cognitive empathy seem to precede the onset of psychotic disorders, suggesting potential targets for future interventions. There is a relationship between empathy and social functioning in this population, with cognitive empathy being lower but affective empathy relatively intact.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Clinical Neurology
Leda L. Talib, Alana C. Costa, Helena P. G. Joaquim, Cicero A. C. Pereira, Martinus T. van de Bilt, Alexandre A. Loch, Wagner F. Gattaz
Summary: The study found significantly increased activities of iPLA(2) and cPLA(2) in UHR individuals, suggesting that PLA(2) activity may serve as a biological risk marker for psychotic disorders.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2021)
Article
Psychology, Multidisciplinary
Jiaojiao Hou, Simon Schmitt, Xudong Zhao, Jiayi Wang, Jianxing Chen, Ziyu Mao, Ansi Qi, Zheng Lu, Tilo Kircher, Yunbo Yang, Jingyu Shi
Summary: Individuals at ultra-high risk for psychosis show no behavioral deficits during facial emotion recognition, but exhibit functional hyperactivities in brain regions associated with this cognitive process.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
Bouwina Esther Sportel, Mirjam van Enthoven, Rozanne J. M. van Donkersgoed, Daan Jan Kuis, Tara van de Giessen, Paul H. Lysaker, Ilanit Hasson-Ohayon, Steven de Jong, Nynke Boonstra, Gerdina H. M. Pijnenborg
Summary: This study aimed to investigate whether self-stigma is already present in individuals at ultra-high risk of developing psychosis, and whether this is associated with impaired cognitive insight. The findings showed that self-stigma was already present in the ultra-high risk phase, to a similar degree as in individuals with a diagnosis of a schizophrenia spectrum disorder. While cognitive insight in individuals at ultra-high risk of psychosis appears to be intact, those individuals showed more self-reflectiveness and those at risk with high cognitive insight also reported high levels of self-stigma.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Ricardo E. Carrion, Andrea M. Auther, Danielle Mclaughlin, Steven Adelsheim, Cynthia Z. Burton, Cameron S. Carter, Tara Niendam, J. Daniel Ragland, Tamara G. Sale, Stephan F. Taylor, Ivy F. Tso, William R. McFarlane, Barbara A. Cornblatt
Summary: The association between cannabis use and psychosis is inconsistent, especially in individuals at clinical high risk for psychosis. However, this study found that continuous cannabis use in CHR youth was associated with improved neurocognition and social functioning over time, as well as decreased medication usage. Surprisingly, clinical symptoms also improved despite the decrease in medication.
PSYCHIATRY RESEARCH
(2023)
Article
Nutrition & Dietetics
Ariel Frajerman, Boris Chaumette, Dominique Farabos, Gaetan Despres, Christelle Simonard, Antonin Lamaziere, Marie-Odile Krebs, Oussama Kebir
Summary: This study explored the role of sterols, fatty acids, and phospholipids in individuals at ultra-high risk of psychosis for the first time. The study found that elevated baseline membrane linoleic acid level was associated with conversion to psychosis, and combining sterols, fatty acids, and phospholipids improved the prediction of psychosis onset.
Article
Psychiatry
Laila Hasmi, Lotta-Katrin Pries, Margreet ten Have, Ron de Graaf, Saskia van Dorsselaer, Maarten Bak, Gunter Kenis, Alexander Richards, Bochao D. Lin, Michael C. O'Donovan, Jurjen J. Luykx, Bart P. F. Rutten, Sinan Guloksuz, Jim van Os
Summary: Research shows that in clinical high-risk states, the co-occurrence of NPD with attenuated psychotic symptoms can influence the risk of developing psychotic disorders, and early psychotic experiences combined with NPD often result in poorer functional outcomes and environmental risks.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2021)
Review
Psychiatry
Patrick D. McGorry, Cristina Mei, Jessica Hartmann, Alison R. Yung, Barnaby Nelson
Summary: This passage discusses the research findings on the efficacy of interventions for the UHR population and explores the optimal types of interventions, highlighting the clinical benefits of psychosocial treatment.
SCHIZOPHRENIA RESEARCH
(2021)
Article
Psychiatry
Frederike Schirmbeck, Nadine C. van der Burg, Matthijs Blankers, Jentien M. Vermeulen, Philip McGuire, Lucia R. Valmaggia, Matthew J. Kempton, Mark van der Gaag, Anita Riecher-Rossler, Rodrigo A. Bressan, Neus Barrantes-Vidal, Barnaby Nelson, G. Paul Amminger, Patrick McGorry, Christos Pantelis, Marie-Odile Krebs, Stephan Ruhrmann, Gabriele Sachs, Bart P. F. Rutten, Jim van Os, Merete Nordentoft, Birte Glenthoj, Paolo Fusar-Poli, Lieuwe de Haan
Summary: This study found that a past depressive episode in UHR individuals is associated with a higher risk of an unfavorable course of APS, while past or current anxiety disorders may be associated with a lower risk of an unfavorable course. Additionally, past depression is significantly associated with a higher risk of transitioning to psychosis.
SCHIZOPHRENIA BULLETIN
(2022)
Article
Psychology, Clinical
Vincent Paquin, Lani Cupo, Ashok K. Malla, Srividya N. Iyer, Ridha Joober, Jai L. Shah
Summary: This study aimed to investigate the association between the first identifiable symptom and the subsequent speed of illness progression in psychosis. The findings showed that having a subthreshold psychotic symptom as the first symptom was not associated with the time to first-episode psychosis onset but was associated with a higher symptom incidence rate. Meanwhile, a first symptom of suspiciousness was associated with a shorter time to onset and a higher symptom incidence rate, while a first symptom of self-harm was associated with a lower symptom incidence rate.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Sarah McIlwaine, M. Ferrari, S. Iyer, A. Malla, J. Shah
Summary: This article describes how young people with mental health problems seek help and access clinical high risk for psychosis (CHR) services. Interviews with eleven participants at a CHR service in Montreal, Canada revealed that participants' difficulties with mental health hindered their everyday activities, leading them to seek out services. The study also found that long wait times and other challenges were experienced during the mental health care journey, but strong collaboration between services facilitated rapid access to care.
PSYCHOSIS-PSYCHOLOGICAL SOCIAL AND INTEGRATIVE APPROACHES
(2023)
Article
Psychiatry
Gil Grunfeld, Ann-Catherine Lemonde, Ian Gold, Srividya N. Iyer, Ashok Malla, Martin Lepage, Ridha Joober, Patricia Boksa, Jai L. Shah
Summary: The study found relatively stable prevalence of delusional themes across cohorts of individuals experiencing first episode psychosis over a period of 12 years. Gender and education level remained stable across different cohorts, while patient age varied.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2023)
Article
Psychiatry
Srividya N. Iyer, Aarati Taksal, Ashok Malla, Helen Martin, Mary Anne Levasseur, Megan A. Pope, Thara Rangaswamy, Padmavati Ramachandran, Greeshma Mohan
Summary: Despite the lack of research in patients' and families' experiences of care in early intervention services for psychosis, this study aimed to compare the experiences in two similar services in different countries. The authors developed a new measure called "Show me you care" which was evaluated in terms of reliability, validity, and usability. The measure showed promise for global application as it was co-designed, developed in multiple languages, and tested in different income contexts.
EARLY INTERVENTION IN PSYCHIATRY
(2023)
Article
Health Policy & Services
Amanda Kwan, Kim Conroy, Keri Barron, Nadia Nandlall, Srividya N. Iyer, J. L. Henderson, Skye Barbic
Summary: In 2021, BC Interior experienced unprecedented disasters, including extreme heat, wildfires, flooding, and COVID-19 outbreaks. Despite these challenges, youth in BC were provided with access to mental health services through adaptions in Foundry Penticton. This Open Forum discusses the program considerations and adaptations made to ensure service delivery during acute and chronic disasters.
PSYCHIATRIC SERVICES
(2023)
Review
Health Policy & Services
Sakiko Yamaguchi, Naima Bentayeb, Alexandra Holtom, Paula Molnar, Teodora Constantinescu, E. Kay M. Tisdall, Josie Tuong, Srividya N. Iyer, Monica Ruiz-Casares
Summary: This study conducted a scoping review to examine the participation of children and youth in mental health policymaking. It found a lack of diversity among the youth involved, with most participation focused on situational analysis and policy design rather than implementation and evaluation. The facilitators and barriers to participation were found to be complex and interconnected. Although there were expected outcomes for youth, adults, organizations, and communities, the actual effects of participation were not extensively explored or reported.
ADMINISTRATION AND POLICY IN MENTAL HEALTH AND MENTAL HEALTH SERVICES RESEARCH
(2023)
Article
Health Policy & Services
Sakiko Yamaguchi, Josie Tuong, E. Kay M. Tisdall, Naima Bentayeb, Alexandra Holtom, Srividya N. Iyer, Monica Ruiz-Casares
Summary: This study conducted global consultations with stakeholders involved in mental health policymaking to gather perspectives on the findings of a scoping review on youth participation in this area. The findings showed that youth often face exclusion and tokenism in the policymaking process, while adults highlighted challenges such as the need for political knowledge and time constraints. Various cultural, socio-economic, and political barriers to youth participation were also identified. Recommendations include recognizing lived experience as expertise, including diverse groups, reducing tokenistic relationships, and adopting an intersectional approach. This study highlights the importance of stakeholder consultations in scoping reviews.
ADMINISTRATION AND POLICY IN MENTAL HEALTH AND MENTAL HEALTH SERVICES RESEARCH
(2023)
Article
Psychiatry
Swaran P. Singh, Catherine Winsper, Mohapradeep Mohan, Max Birchwood, Rakesh K. Chadda, Vivek Furtado, Srividya N. Iyer, Richard J. Lilford, Jason Madan, Caroline Meyer, Padmavati Ramachandran, Thara Rangaswamy, Jai Shah, Mamta Sood
Summary: Developing countries like India have a significant gap in mental health care. This study compares the care pathways for first episode psychosis patients in North and South India to address the treatment gap.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Psychology, Developmental
Jai L. Shah, Vincent Paquin, Sarah V. McIlwaine, Ashok K. Malla, Ridha Joober, Marita Pruessner
Summary: The stress-vulnerability model has been widely studied in relation to psychosis. However, there are few studies comparing stress response across stages of illness. This study examined the psychobiological response to stress in clinical high-risk and first-episode psychosis patients and found that individual stress response markers may differentially emerge at particular stages en route to psychosis.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2023)
Article
Anthropology
Anika Maraj, Manuela Ferrari, Kathleen MacDonald, Matthew Peters, Ridha Joober, Jai L. Shah, Srividya N. Iyer
Summary: Language status has an impact on healthcare accessibility and outcomes, but its influence on treatment engagement and disengagement is unclear. This study investigates the impact of language on service disengagement in a psychosis program, comparing English and French speakers. The findings show that language preference affects service engagement, highlighting the importance of communication and cultural understanding in clinical settings.
TRANSCULTURAL PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Gerald Jordan, Christina Mutschler, Sean A. A. Kidd, Michael Rowe, Srividya N. N. Iyer
Summary: This paper discusses how youth mental health services in Canada can help young people recover a sense of citizenship by addressing social issues, developing a citizenship-based system of care, addressing identity-related disparities, and more.
JOURNAL OF PUBLIC MENTAL HEALTH
(2023)
Article
Psychology, Clinical
Vincent Paquin, Ashok K. K. Malla, Srividya N. N. Iyer, Martin Lepage, Ridha Joober, Jai L. L. Shah
Summary: Across subthreshold psychotic and nonpsychotic syndromes, pre-onset self-harm and suicide attempts are associated with more severe positive, depressive, and anxiety symptoms during the follow-up period after the first episode of psychosis. However, pre-onset subthreshold psychotic symptoms do not have a significant impact on outcomes, except for a slightly different trajectory of functioning.
JOURNAL OF PSYCHOPATHOLOGY AND CLINICAL SCIENCE
(2023)
Review
Public, Environmental & Occupational Health
Tanya Halsall, Kianna Mahmoud, Srividya N. Iyer, Heather Orpana, Megan Zeni, Kimberly Matheson
Summary: This research examines the implementation of the Icelandic Prevention Model (IPM) in Canada and identifies opportunities to re-design the social eco-system to promote wellbeing revealed by the COVID-19 pandemic. The study finds that patterns of time and space use and family and community cohesion influence youth substance use. The pandemic presents opportunities for promoting youth wellbeing. The concepts of time and space are used to discuss implications for policy and practice.
INTERNATIONAL JOURNAL OF QUALITATIVE STUDIES ON HEALTH AND WELL-BEING
(2023)
