IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling

Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma

(2016) Hui-Hui Cao et al.   Scientific Reports

Melanoma and the Unfolded Protein Response

(2016) Erin Sykes et al.   Cancers

Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses

(2015) Yang Liu et al.   JOURNAL OF HEPATOLOGY

Proteome Analysis of Renoprotection Mediated by a Novel Cyclic Helix B Peptide in Acute Kidney Injury

(2015) Cheng Yang et al.   Scientific Reports

Human Melanoma Cells under Endoplasmic Reticulum Stress Acquire Resistance to Microtubule-Targeting Drugs through XBP-1-Mediated Activation of Akt

(2015) Chen Chen Jiang et al.   NEOPLASIA

A novel proteolysis-resistant cyclic helix B peptide ameliorates kidney ischemia reperfusion injury

(2014) Cheng Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma

(2014) M Corazzari et al.   CELL DEATH AND DIFFERENTIATION

The IRE1α-XBP1 pathway regulates metabolic stress-induced compensatory proliferation of pancreatic β-cells

(2014) Tongfu Xu et al.   CELL RESEARCH

Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma

(2014) Xiao-Hong Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum-stabilized Naked Caspase-3 siRNA Protects Autotransplant Kidneys in a Porcine Model

(2014) Cheng Yang et al.   MOLECULAR THERAPY

Oncogenic Activation of MEK/ERK Primes Melanoma Cells for Adaptation to Endoplasmic Reticulum Stress

(2013) Amanda Croft et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IRE1α-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis

(2012) Shiyu Wang et al.   Cell Metabolism

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism

(2012) Yingfeng Deng et al.   JOURNAL OF CLINICAL INVESTIGATION

Vitiligo-Inducing Phenols Activate the Unfolded Protein Response in Melanocytes Resulting in Upregulation of IL6 and IL8

(2012) Siavash Toosi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interleukin-6 and melanoma

(2012) Lise Hoejberg et al.   MELANOMA RESEARCH

Serum interleukin-6 as a prognostic biomarker in patients with metastatic melanoma

(2012) Lise Hoejberg et al.   MELANOMA RESEARCH

Activation of PI3K/AKT and MAPK Pathway through a PDGFRβ-Dependent Feedback Loop Is Involved in Rapamycin Resistance in Hepatocellular Carcinoma

(2012) Quan-Lin Li et al.   PLoS One

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer-Initiating Cells

(2011) L. Lin et al.   CANCER RESEARCH

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction

(2011) Yingjiang Zhou et al.   NATURE MEDICINE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

(2010) Fabio Martinon et al.   NATURE IMMUNOLOGY

IRE1α controls cyclin A1 expression and promotes cell proliferation through XBP-1

(2009) Jeffery A. Thorpe et al.   CELL STRESS & CHAPERONES

Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma

(2009) Liquing Zhuang et al.   HISTOPATHOLOGY

Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma

(2008) Peter Hersey et al.   Pigment Cell & Melanoma Research