Anticancer effects of seaweed compounds fucoxanthin and phloroglucinol, alone and in combination with 5-fluorouracil in colon cells

Structural characterization and comparative biomedical properties of phloroglucinol from Indian brown seaweeds

(2016) Ramachandran Karthik et al.   JOURNAL OF APPLIED PHYCOLOGY

Essential and toxic elements in seaweeds for human consumption

(2016) D. Desideri et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Bioactive compounds from brown seaweeds: Phloroglucinol, fucoxanthin and fucoidan as promising therapeutic agents against breast cancer

(2015) D. Pádua et al.   Phytochemistry Letters

Effects of 5-Fluorouracil on Morphology, Cell Cycle, Proliferation, Apoptosis, Autophagy and ROS Production in Endothelial Cells and Cardiomyocytes

(2015) Chiara Focaccetti et al.   PLoS One

In Vitro and in Vivo Evaluation of the Antioxidant and Prooxidant Activity of Phenolic Compounds Obtained from Grape (Vitis vinifera) Pomace

(2014) Milena Cotoras et al.   MOLECULES

Phloroglucinol induces apoptosis via apoptotic signaling pathways in HT-29 colon cancer cells

(2014) MI-HYE KANG et al.   ONCOLOGY REPORTS

Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation

(2014) Y Fu et al.   Cell Death & Disease

Cytotoxic activity of acyl phloroglucinols isolated from the leaves of Eucalyptus cinerea F. Muell. ex Benth. cultivated in Egypt

(2014) Fathy M. Soliman et al.   Scientific Reports

Antiproliferative activity of the dimeric phloroglucinol and benzophenone derivatives of Hypericum spp. native to southern Brazil

(2013) Amanda V. Pinhatti et al.   ANTI-CANCER DRUGS

Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties

(2013) Jin-Ching Lee et al.   Cancer Cell International

Synergistic antitumor effect of 5-fluorouracil in combination with parthenolide in human colorectal cancer

(2013) Se-Lim Kim et al.   CANCER LETTERS

Anti-diabetic effects of brown algae derived phlorotannins, marine polyphenols through diverse mechanisms

(2013) Seung-Hong Lee et al.   FITOTERAPIA

Fucoxanthin: A Marine Carotenoid Exerting Anti-Cancer Effects by Affecting Multiple Mechanisms

(2013) Sangeetha Kumar et al.   Marine Drugs

Epigenetic and genetic features of 24 colon cancer cell lines

(2013) D Ahmed et al.   Oncogenesis

Carotenoids reverse multidrug resistance in cancer cells by interfering with ABC-transporters

(2012) Safaa Yehia Eid et al.   PHYTOMEDICINE

Chromosomal Instability Confers Intrinsic Multidrug Resistance

(2011) A. J. X. Lee et al.   CANCER RESEARCH

Fucoxanthin, a Marine Carotenoid Present in Brown Seaweeds and Diatoms: Metabolism and Bioactivities Relevant to Human Health

(2011) Juan Peng et al.   Marine Drugs

5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency

(2010) K Bracht et al.   BRITISH JOURNAL OF CANCER

Phloroglucinol (1,3,5-trihydroxybenzene) protects against ionizing radiation-induced cell damage through inhibition of oxidative stress in vitro and in vivo

(2010) Kyoung Ah Kang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway

(2010) Rui-xue Yu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism

(2010) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

Protective effects of Ursolic acid and Luteolin against oxidative DNA damage include enhancement of DNA repair in Caco-2 cells

(2010) Alice A. Ramos et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses

(2010) Jaouad Bouayed et al.   Oxidative Medicine and Cellular Longevity

Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway

(2010) Kil-Nam Kim et al.   TOXICOLOGY IN VITRO

Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells

(2009) Jie Li et al.   ANNALS OF SURGICAL ONCOLOGY

Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication

(2009) Cheng-Ling Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Phloroglucinol compounds of therapeutic interest: global patent and technology status

(2009) Inder Pal Singh et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells

(2009) Chang-Suk Kong et al.   FOOD AND CHEMICAL TOXICOLOGY

Preventive effects of Chlorella on cognitive decline in age-dependent dementia model mice

(2009) Yuya Nakashima et al.   NEUROSCIENCE LETTERS

Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors

(2009) Fatima Haggar et al.   Clinics in Colon and Rectal Surgery

5-Fluorouracil: Mechanisms of Resistance and Reversal Strategies

(2008) Ning Zhang et al.   MOLECULES

The comet assay: topical issues

(2008) A. R. Collins et al.   MUTAGENESIS