Platelet RNA as a circulating biomarker trove for cancer diagnostics

Hyperglycaemia suppresses microRNA expression in platelets to increase P2RY12 and SELP levels in type 2 diabetes mellitus

(2017) Zsolt Fejes et al.   THROMBOSIS AND HAEMOSTASIS

Assessing blood platelets as RNA biomarker source for prostate cancer

(2016) Jörg Hänze et al.   BIOMARKERS

Platelets enrich their transcriptome circle

(2016) Patrick Provost   BLOOD

Hunting for the ultimate liquid cancer biopsy - let the TEP dance begin

(2016) Stephan M. Feller et al.   Cell Communication and Signaling

Platelets are not hyperreactive in patients with ovarian cancer

(2016) Shuju Feng et al.   PLATELETS

Platelet microparticles reprogram macrophage gene expression and function

(2016) Matthieu Rousseau et al.   THROMBOSIS AND HAEMOSTASIS

Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response

(2016) Jan Rossaint et al.   Nature Communications

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells

(2016) Amit Grover et al.   Nature Communications

Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets

(2016) Eric W. Mills et al.   Cell Reports

Time-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation Activity

(2016) Catherine Angénieux et al.   PLoS One

Transcriptome Profile of the Chicken Thrombocyte: New Implications as an Advanced Immune Effector Cell

(2016) Farzana Ferdous et al.   PLoS One

Circular RNA enrichment in platelets is a signature of transcriptome degradation

(2015) Abd A. Alhasan et al.   BLOOD

Horizontal RNA transfer mediates platelet-induced hepatocyte proliferation

(2015) M. Kirschbaum et al.   BLOOD

RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

(2015) Myron G. Best et al.   CANCER CELL

Association of MicroRNAs and YRNAs With Platelet FunctionNovelty and Significance

(2015) Dorothee Kaudewitz et al.   CIRCULATION RESEARCH

Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction

(2015) John D. Eicher et al.   PLATELETS

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA

(2015) Anne-Claire Duchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer

(2015) Rui Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating stimuli induce platelet microRNA modulation and proteome reorganisation

(2015) Giovanni Nassa et al.   THROMBOSIS AND HAEMOSTASIS

Breaking the Mold: Transcription Factors in the Anucleate Platelet and Platelet-Derived Microparticles

(2015) Katie L. Lannan et al.   Frontiers in Immunology

Does thrombopoiesis in multiple myeloma patients depend on the stage of the disease?

(2014) Joanna Kamińska et al.   Advances in Medical Sciences

Mechanism of Race-Dependent Platelet Activation Through the Protease-Activated Receptor-4 and Gq Signaling Axis

(2014) Benjamin E. Tourdot et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome

(2014) Eric R Londin et al.   Biology Direct

A tour through the transcriptional landscape of platelets

(2014) S. Schubert et al.   BLOOD

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics

(2014) L. M. Simon et al.   BLOOD

Platelets and cancer: a casual or causal relationship: revisited

(2014) David G. Menter et al.   CANCER AND METASTASIS REVIEWS

Differential Platelet Levels Affect Response to Taxane-Based Therapy in Ovarian Cancer

(2014) Justin Bottsford-Miller et al.   CLINICAL CANCER RESEARCH

The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

(2014) Sandra S. McAllister et al.   NATURE CELL BIOLOGY

Platelets guide the formation of early metastatic niches

(2014) M. Labelle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

(2014) Danijela Koppers-Lalic et al.   Cell Reports

Activated platelets can deliver mRNA regulatory Ago2bulletmicroRNA complexes to endothelial cells via microparticles

(2013) B. Laffont et al.   BLOOD

Coordinate expression of transcripts and proteins in platelets

(2013) J. W. Rowley et al.   BLOOD

The complex transcriptional landscape of the anucleate human platelet

(2013) Paul F Bray et al.   BMC GENOMICS

Platelets and Inflammatory Markers in Patients with Gastric Cancer

(2013) Joanna Matowicka-Karna et al.   Clinical & Developmental Immunology

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

(2013) Alejandra Sanjuan-Pla et al.   NATURE

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c

(2013) Leonard C Edelstein et al.   NATURE MEDICINE

Next Generation Sequencing Analysis of Human Platelet PolyA+ mRNAs and rRNA-Depleted Total RNA

(2013) Antheia Kissopoulou et al.   PLoS One

VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients

(2012) Jon E. Peterson et al.   ANGIOGENESIS

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

(2012) J. M. Burkhart et al.   BLOOD

Platelets increase the proliferation of ovarian cancer cells

(2012) M. S. Cho et al.   BLOOD

Systematic analysis of microRNA fingerprints in thrombocythemic platelets using integrated platforms

(2012) X. Xu et al.   BLOOD

Platelets and platelet-like particles mediate intercellular RNA transfer

(2012) A. Risitano et al.   BLOOD

Paraneoplastic Thrombocytosis in Ovarian Cancer

(2012) Rebecca L. Stone et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Repertoire and Features of Human Platelet microRNAs

(2012) Hélène Plé et al.   PLoS One

Micro-array profiling exhibits remarkable intra-individual stability of human platelet micro-RNA

(2012) Christian Stratz et al.   THROMBOSIS AND HAEMOSTASIS

Identification of Luminal Breast Cancers That Establish a Tumor-Supportive Macroenvironment Defined by Proangiogenic Platelets and Bone Marrow-Derived Cells

(2012) H. S. Kuznetsov et al.   Cancer Discovery

Alzheimer disease and platelets: how’s that relevant

(2012) Silvia Catricala et al.   Immunity & Ageing

Platelets in pulmonary vascular physiology and pathology

(2012) Michael H. Kroll et al.   Pulmonary Circulation

Megakaryocytes differentially sort mRNAs for matrix metalloproteinases and their inhibitors into platelets: a mechanism for regulating synthetic events

(2011) L. Cecchetti et al.   BLOOD

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes

(2011) J. W. Rowley et al.   BLOOD

Blood platelets contain tumor-derived RNA biomarkers

(2011) R. J. A. Nilsson et al.   BLOOD

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells

(2011) T. Placke et al.   CANCER RESEARCH

Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1 -Rich Microparticles

(2011) G. T. Brown et al.   JOURNAL OF IMMUNOLOGY

Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease

(2010) C. Lood et al.   BLOOD

Relation of Platelet and Leukocyte Inflammatory Transcripts to Body Mass Index in the Framingham Heart Study

(2010) Jane E. Freedman et al.   CIRCULATION

Significant Downregulation of Platelet Gene Expression in Metastatic Lung Cancer

(2010) David C. Calverley et al.   CTS-Clinical and Translational Science

The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing

(2010) Shivendra Kishore et al.   HUMAN MOLECULAR GENETICS

Platelet activation in patients with advanced gastric cancer

(2010) J. Osada et al.   NEOPLASMA

Beyond Clotting: The Powers of Platelets

(2010) M. Leslie   SCIENCE

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

(2010) E. Boilard et al.   SCIENCE

Class prediction models of thrombocytosis using genetic biomarkers

(2009) D. V. Gnatenko et al.   BLOOD

Existence of a microRNA pathway in anucleate platelets

(2009) Patricia Landry et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Signal-Dependent Protein Synthesis by Activated Platelets

(2008) Guy A. Zimmerman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelets actively sequester angiogenesis regulators

(2008) G. Lakka Klement et al.   BLOOD