Novel insights into the regulation of coagulation by factor V isoforms, tissue factor pathway inhibitorα, and protein S

Rethinking events in the haemostatic process: role of factor V and TFPI

(2016) R. M. Camire   HAEMOPHILIA

Pro- and anticoagulant properties of factor V in pathogenesis of thrombosis and bleeding disorders

(2016) Björn Dahlbäck   International Journal of Laboratory Hematology

Identification and functional characterization of a novel F5 mutation (Ala512Val, FVB onn ) associated with activated protein C resistance

(2016) B. Pezeshkpoor et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The C-terminus of tissue factor pathway inhibitor-α inhibits factor V activation by protecting the Arg1545cleavage site

(2016) P. van Doorn et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Role of exosite binding modulators in the inhibition of Fxa by TFPI

(2016) Alexandra Heinzmann et al.   THROMBOSIS AND HAEMOSTASIS

A novel mutation in the F5 gene (factor V Amsterdam) associated with bleeding independent of factor V procoagulant function

(2015) M. L. R. Cunha et al.   BLOOD

New insights into the biology of tissue factor pathway inhibitor

(2015) S. A. Maroney et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Polyphosphate as modulator of hemostasis, thrombosis, and inflammation

(2015) J. H. Morrissey et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

New insights into the spatiotemporal localization of prothrombinase in vivo

(2014) L. Ivanciu et al.   BLOOD

Novel FV mutation (W1920R, FVNara) associated with serious deep vein thrombosis and more potent APC resistance relative to FVLeiden

(2014) K. Nogami et al.   BLOOD

Protein S Is a Cofactor for Platelet and Endothelial Tissue Factor Pathway Inhibitor-α but Not for Cell Surface–Associated Tissue Factor Pathway Inhibitor

(2013) Jeremy P. Wood et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis

(2013) B. C. Lechtenberg et al.   BLOOD

Restoring the Procofactor State of Factor Va-like Variants by Complementation with B-domain Peptides

(2013) Matthew W. Bunce et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Factor V, tissue factor pathway inhibitor, and east Texas bleeding disorder

(2013) George J. Broze et al.   JOURNAL OF CLINICAL INVESTIGATION

Coagulation factor VA2440G causes east Texas bleeding disorder via TFPIα

(2013) Lisa M. Vincent et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteolysis of plasma-derived factor V following its endocytosis by megakaryocytes forms the platelet-derived factor V/Va pool

(2013) F. Ayombil et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The transition of prothrombin to thrombin

(2013) S. Krishnaswamy   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation

(2013) J. P. Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parahemophilia: New Insights into Factor V Deficiency

(2013) Nabil Thalji et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S

(2012) J. Ahnstrom et al.   BLOOD

Protein C anticoagulant and cytoprotective pathways

(2012) John H. Griffin et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

A Bipartite Autoinhibitory Region within the B-domain Suppresses Function in Factor V

(2012) Mettine H. A. Bos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The C-terminus of tissue factor pathway inhibitor α is required for its interaction with factors V and Va

(2012) M. NDONWI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet tissue factor pathway inhibitor modulates intravascular coagulation

(2012) Susan A. Maroney et al.   THROMBOSIS RESEARCH

TFPI-dependent activities of Protein S

(2012) Sameera Peraramelli et al.   THROMBOSIS RESEARCH

TFPI  is the GPI-anchored TFPI isoform on human endothelial cells and placental microsomes

(2011) T. J. Girard et al.   BLOOD

Structural basis of coagulation factor V recognition for cleavage by RVV-V

(2011) Daisuke Nakayama et al.   FEBS LETTERS

Tissue factor pathway inhibitor: structure-function

(2011) George et al.   Frontiers in Bioscience-Landmark

Properties of Procoagulant Platelets

(2010) Ammon M. Fager et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Kunitz-3 domain of TFPI-  is required for protein S-dependent enhancement of factor Xa inhibition

(2010) M. Ndonwi et al.   BLOOD

Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms

(2009) C. Duckers et al.   BLOOD

Basic mechanisms and pathogenesis of venous thrombosis

(2009) Charles T. Esmon   BLOOD REVIEWS

Advances in understanding the bleeding diathesis in factor V deficiency

(2009) Connie Duckers et al.   BRITISH JOURNAL OF HAEMATOLOGY

APC resistance: biological basis and acquired influences

(2009) E. CASTOLDI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The molecular basis of factor V and VIII procofactor activation

(2009) R. M. CAMIRE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Regulation of TFPI function by protein S

(2009) T. M. HACKENG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma

(2009) E. CASTOLDI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Factor V Deficiency

(2009) Rosanna Asselta et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Advances in understanding pathogenic mechanisms of thrombophilic disorders

(2008) B. Dahlback   BLOOD

Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency

(2008) C. Duckers et al.   BLOOD

Effects of Prothrombin on the Individual Activated Protein C-mediated Cleavages of Coagulation Factor Va

(2008) Sinh Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping of the Factor Xa Binding Site on Factor Va by Site-directed Mutagenesis

(2008) Mårten Steen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY