Article
Cardiac & Cardiovascular Systems
Nathalie Mini, Peter A. Zartner, Martin B. E. Schneider
Summary: This study aimed to explore the diagnostic value of the ratio between pulmonary and systemic blood flow (Qp/Qs) in patients with severe coarctation of the aorta (CoA). By retrospectively analyzing the cardiac catheterization data of 78 CoA patients, the results showed a significant correlation between Qp/Qs and the severity and prognosis of the heart condition.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Caecilia Euringer, Thibault Schaeffer, Paul Philipp Heinisch, Melchior Burri, Stanimir Georgiev, Julia Lemmer, Peter Ewert, Alfred Hager, Juergen Hoerer, Masamichi Ono
Summary: This study aimed to determine whether the size of the pulmonary artery (PA) affects survival and if an additional aortopulmonary shunt (APS) promotes left PA growth in patients with hypoplastic left heart syndrome who underwent bidirectional cavopulmonary shunt (BCPS). The study found that preoperative PA index did not affect mortality after BCPS, and the additional APS was unable to improve left PA size in patients with inadequate BCPS.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Ahmed F. Elmahrouk, Mohamed F. Ismail, Amr A. Arafat, Ahmed M. Dohain, Azzahra M. Edrees Mbbs, Ahmed A. Jamjoom Mbbs, Osman O. Al-Radi
Summary: This study demonstrates the feasibility of using a primary cavopulmonary shunt as part of the initial Norwood palliation in patients with unrestricted pulmonary blood flow and low pulmonary vascular resistance. Delayed chest closure and postoperative inhaled nitric oxide were required in some patients, but overall results suggest that the initial use of the cavopulmonary shunt is effective and provides a foundation for further surgical strategies.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Takashi Kido, Melchior Burri, Benedikt Mayr, Martina Strbad, Julie Cleuziou, Alfred Hager, Juergen Hoerer, Masamichi Ono
Summary: This study aimed to assess the impact of high mean pulmonary artery pressure before bidirectional cavopulmonary shunt on late adverse events in low pulmonary artery pressure patients before total cavopulmonary connection (TCPC). Results showed that high mean pulmonary artery pressure remained a significant risk factor for adverse events after TCPC, even if the pressure decreased below 10mmHg before TCPC. Various factors such as previous atrial septectomy and pulmonary artery banding were associated with different pressure levels before TCPC.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Helena Staehler, Thibault Schaeffer, Johanna Wasner, Julia Lemmer, Michel Adam, Melchior Burri, Alfred Hager, Peter Ewert, Juergen Hoerer, Masamichi Ono, Paul Philipp Heinisch
Summary: A home monitoring program (HMP) can decrease interstage mortality for patients with hypoplastic left heart syndrome before undergoing bidirectional cavopulmonary shunt (BCPS). HMP allows for timely intervention and reduces the risk of interstage mortality.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Garrett N. Coyan, Carlos Diaz-Castrillon, Mario Castro-Medina, Luciana Da Fonseca Da Silva, Melita Viegas, Victor O. Morell
Summary: High-risk status in patients undergoing stage 1 palliation is associated with increased mortality, length of stay, and readmission rates after stage 2 palliation. However, high-risk patients have similar survival to low-risk patients after stage 3 palliation.
ANNALS OF THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Isaac Wamala, Kevin G. Friedman, Mossab Y. Saeed, Kimberlee Gauvreau, Laura Gellis, Michele Borisuk, Aditya Kaza, Sitaram Emani, Pedro J. del Nido, Christopher W. Baird
Summary: The study aimed to describe the outcomes of tricuspid valve reconstruction (TVR) concomitant with the Norwood operation in patients with hypoplastic left heart syndrome (HLHS) and evaluate the structural factors associated with successful functional correction. The study found that improvement in tricuspid regurgitation (TR) grade and having mild TR at discharge were associated with improved reintervention and TR-free survival. Patients with successful functional correction had smaller preoperative tricuspid annulus lateral dimensions, tricuspid valve area, and right ventricle midwidth.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Masamichi Ono, Takashi Kido, Marie Wallner, Melchior Burri, Julia Lemmer, Peter Ewert, Martina Strbad, Julie Cleuziou, Alfred Hager, Jurgen Hoerer
Summary: This study evaluated the outcomes of neonates undergoing the Norwood procedure with modified Blalock-Taussig shunt (MBTS) or right ventricular-pulmonary artery conduit (RVPAC). The results showed no significant difference in early mortality, inter-stage attritions, or overall survival between the two types of shunts during a maximum follow-up period of 18.8 years.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Makoto Miyake, Jiro Sakamoto, Hirokazu Kondo, Atsushi Iwakura, Hiraku Doi, Toshihiro Tamura
Summary: This study aimed to investigate the long-term outcomes of patients with single-ventricle physiology after the Glenn procedure without the subsequent Fontan procedure. The study found that the 40-year overall survival after the Glenn procedure in patients with single-ventricle physiology was 40.3%. Dominant left ventricular morphology may be associated with better long-term overall survival than dominant right ventricular morphology.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Koji Miwa, Shigemitsu Iwai, Tomomitsu Kanaya, Shota Kawai
Summary: This study compared the surgical outcomes and hemodynamics in children with hypoplastic left heart syndrome who underwent the Norwood operation preceded by bilateral pulmonary artery banding, with either a right ventricular-pulmonary artery shunt or bidirectional Glenn anastomosis. The results showed similar pressures after the Fontan procedure in both groups, but significantly lower superior vena cava pressure after bidirectional Glenn anastomosis in the comprehensive stage II strategy group. However, the right ventricular-pulmonary artery shunt adversely influenced right ventricular volume.
PEDIATRIC CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Rasmus Kristensen, Benjamin Kelly, Emily Kim, Yoav Dori, Vibeke E. Hjortdal
Summary: This study retrospectively reviewed patients with single-ventricle physiology who underwent T2-weighted magnetic resonance imaging before the Glenn operation at The Children's Hospital of Philadelphia from 2012 to 2022. The results showed that lymphatic abnormalities were present in 21% of patients, with 20% being severe abnormalities, and 59% of patients had normal lymphatic perfusion patterns. Patients with severe lymphatic abnormalities had higher mortality and chylothorax rates.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Sebastian Rimpau, Kristen Gibbons, Prem Venugopal, Nelson Alphonso, Benjamin Anderson, Kerry E. Johnson, Adrian C. Mattke
Summary: This study retrospectively evaluated the outcomes of Norwood procedures performed at Queensland Children's Hospital over the past 6 years. The results demonstrate that the Norwood program at this center has achieved comparable results to other established centers and the international literature.
HEART LUNG AND CIRCULATION
(2022)
Article
Cardiac & Cardiovascular Systems
Kendall M. Lawrence, Richard F. Ittenbach, Mallory L. Hunt, Michelle Kaplinski, Chitra Ravishankar, Jack Rychik, James M. Steven, Stephanie M. Fuller, Susan C. Nicolson, J. William Gaynor, Thomas L. Spray, Christopher E. Mascio
Summary: In children with hypoplastic left heart syndrome who survived superior cavopulmonary connection, over three decades, over 8% failed to undergo the Fontan procedure and this rate has remained stable. The use of a right ventricle to pulmonary artery shunt during the Norwood procedure was associated with increased attrition.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
George M. Hoffman, Robert A. Niebler, John P. Scott, Rebecca A. Bertrandt, Martin K. Wakeham, Nathan E. Thompson, Nancy S. Ghanayem, Eckehard A. Stuth, Michael E. Mitchell, Ronald K. Woods, Viktor Hraska, Kathleen A. Mussatto, James S. Tweddell
Summary: This study identified interventions associated with low-CO state occupancy and transition through bivariate analysis of hemodynamic states. Maintaining or increasing inodilator and hemoglobin levels were found to improve hemodynamic conditions and predict successful transitions from the low-CO state in the future.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Melvin Schmiel, Takashi Kido, Stanimir Georgiev, Melchior Burri, Paul Philipp Heinisch, Janez Vodiskar, Martina Strbad, Peter Ewert, Alfred Hager, Juergen Hoerer, Masamichi Ono
Summary: The incidence and associated factors of aortopulmonary collaterals (APCs) in patients with univentricular heart undergoing staged palliation were examined in this study. The presence of APCs before Glenn shunt was highly associated with hypoplastic left heart syndrome, while lower Nakata-Index and younger age at Glenn shunt were associated with the development of APCs before Fontan procedure. However, the presence of APCs or intervention for APCs did not affect intensive care unit stay or mortality after total cavopulmonary connection.
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Phil Botha, Shriprasad R. Deshpande, Michael Wolf, Micheal Heard, Bahaaldin Alsoufi, Brian Kogon, Kirk Kanter
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2016)
Article
Cardiac & Cardiovascular Systems
Phil Botha, Ruth Solana, Jane Cassidy, Gareth Parry, Richard Kirk, Asif Hasan, Massimo Griselli
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2013)
Article
Cardiac & Cardiovascular Systems
David J. Barron, Dawood K. Mehsood, Ramesh S. Kutty, John Stickley, Phil Botha, Natasha E. Khan, Timothy J. Jones, William J. Brawn
ANNALS OF THORACIC SURGERY
(2019)
Article
Cardiac & Cardiovascular Systems
David J. Barron, Ramesh S. Kutty, John Stickley, Oliver Stuemper, Phil Botha, Natasha E. Khan, Timothy J. Jones, Nigel E. Drury, William J. Brawn
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2019)
Article
Cardiac & Cardiovascular Systems
Mohammad Abumehdi, Mohamed Al Nasef, Chetan Mehta, Phil Botha, Colin McMahon, Paul Oslizlok, Kevin P. Walsh, Brian McCrossan, Damien Kenny, Oliver Stumper
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2020)
Article
Cardiac & Cardiovascular Systems
Mohammad Abumehdi, Deepa Sasikumar, Milind Chaudhari, Vinay Bhole, Phil Botha, Chetan Mehta, Oliver Stumper
Summary: Right ventricular outflow tract stenting is a valuable intervention in patients with Tetralogy of Fallot with pulmonary stenosis and major aortopulmonary collateral arteries, where promoting native pulmonary arterial growth is crucial for repair. The procedure resulted in improved oxygen saturations and increased z scores for both right and left pulmonary arteries, allowing for further catheterization and successful anatomical repair in some cases.
CARDIOLOGY IN THE YOUNG
(2021)
Article
Cardiac & Cardiovascular Systems
Robert G. Willetts, John Stickley, Nigel E. Drury, Chetan Mehta, Oliver Stumper, Natasha E. Khan, Timothy J. Jones, David J. Barron, William J. Brawn, Phil Botha
Summary: The most durable valved right ventricle to pulmonary artery conduit for the repair of congenital heart defects in patients of different ages, sizes, and anatomic substrate remains uncertain. Pulmonary and aortic homografts had greater durability than xenograft conduits, particularly in patients weighing 5 to 20 kg. Judicious oversizing was the most significant surgeon-modifiable factor affecting conduit longevity.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Phil Botha
ANNALS OF THORACIC SURGERY
(2023)
Review
Pediatrics
Snighda M. Reddy, Anthony D. Lander, Oliver Stumper, Phil Botha, Natasha Khan, Max Pachl
Summary: This study presents a series of five surviving patients with esophago-vascular fistulae, proposing a management approach and conducting a literature review. The results show favorable outcomes with multidisciplinary discussion and surgery. Survival to discharge is possible if hemorrhage is controlled, although the surgical intervention involved is significant and high-risk.
JOURNAL OF PEDIATRIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Nigel E. Drury, Shafi Mussa, John Stickley, Oliver Stumper, Adrian Crucean, Rami Dhillon, Anna N. Seale, Phil Botha, Natasha E. Khan, David J. Barron, William J. Brawn, Timothy J. Jones
Summary: This study aimed to describe the early and late outcomes of the arterial switch for transposition. A retrospective cohort study was conducted to assess the outcomes of arterial switch performed between 1988 and 2018, compared by morphological groups. The results showed that using a standardized approach, the arterial switch can be performed with low early mortality, moderate rates of reintervention, and excellent long-term survival.
INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Safak Alpat, Adrian Crucean, Tarak Desai, Simon McGuirk, Robert H. Anderson, Phil Botha, David Barron
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Bahaaldin Alsoufi, Michael Wolf, Phil Botha, Brian Kogon, Courtney McCracken, Alexandra Ehrlich, Kirk Kanter, Shriprasad Deshpande
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
(2015)
Article
Cardiac & Cardiovascular Systems
Phil Botha, Asif Hasan, Gianluigi Perri, Sergio Filippelli, Massimo Griselli
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
(2012)
Article
Cardiac & Cardiovascular Systems
Yaroslav Ivanov, Nigel E. Drury, John Stickley, Phil Botha, Natasha E. Khan, Timothy J. Jones, William J. Brawn, David J. Barron
SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY
(2020)