Bioelectric gene and reaction networks: computational modelling of genetic, biochemical and bioelectrical dynamics in pattern regulation

Gap junctional signaling in pattern regulation: Physiological network connectivity instructs growth and form

(2016) Juanita Mathews et al.   Developmental Neurobiology

Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome

(2016) Dany Spencer Adams et al.   JOURNAL OF PHYSIOLOGY-LONDON

Use of genetically encoded, light-gated ion translocators to control tumorigenesis

(2016) Brook T. Chernet et al.   Oncotarget

Bioelectrical Signals and Ion Channels in the Modeling of Multicellular Patterns and Cancer Biophysics

(2016) Javier Cervera et al.   Scientific Reports

Keppen-Lubinsky Syndrome Is Caused by Mutations in the Inwardly Rectifying K+ Channel Encoded by KCNJ6

(2015) Andrea Masotti et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ion Channels in Development and Cancer

(2015) Emily Bates   Annual Review of Cell and Developmental Biology

Bioelectrical regulation of cell cycle and the planarian model system

(2015) Paul G. Barghouth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bioelectric patterning during oogenesis: stage-specific distribution of membrane potentials, intracellular pH and ion-transport mechanisms in Drosophila ovarian follicles

(2015) Julia Krüger et al.   BMC DEVELOPMENTAL BIOLOGY

The Thermodynamic Driving Force for Kinetics in General and Enzyme Kinetics in Particular

(2015) Miloslav Pekař   CHEMPHYSCHEM

Positional information and reaction-diffusion: two big ideas in developmental biology combine

(2015) J. B. A. Green et al.   DEVELOPMENT

Protein expression profiling in head fragments during planarian regeneration after amputation

(2015) Xiaoguang Chen et al.   DEVELOPMENT GENES AND EVOLUTION

Gap Junctional Blockade Stochastically Induces Different Species-Specific Head Anatomies in Genetically Wild-Type Girardia dorotocephala Flatworms

(2015) Maya Emmons-Bell et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endogenous Gradients of Resting Potential Instructively Pattern Embryonic Neural Tissue via Notch Signaling and Regulation of Proliferation

(2015) V. P. Pai et al.   JOURNAL OF NEUROSCIENCE

Electrical Coupling in Ensembles of Nonexcitable Cells: Modeling the Spatial Map of Single Cell Potentials

(2015) Javier Cervera et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Data-driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud

(2015) M. Uzkudun et al.   Molecular Systems Biology

Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome

(2015) Fanny Kortüm et al.   NATURE GENETICS

Scaling and Regeneration of Self-Organized Patterns

(2015) Steffen Werner et al.   PHYSICAL REVIEW LETTERS

Cancer as a channelopathy: ion channels and pumps in tumor development and progression

(2015) Alisa Litan et al.   Frontiers in Cellular Neuroscience

Comparison of the depolarization response of human mesenchymal stem cells from different donors

(2015) Sarah Sundelacruz et al.   Scientific Reports

Inferring Regulatory Networks from Experimental Morphological Phenotypes: A Computational Method Reverse-Engineers Planarian Regeneration

(2015) Daniel Lobo et al.   PLoS Computational Biology

Single-channel kinetics of BK (Slo1) channels

(2015) Yanyan Geng et al.   Frontiers in Physiology

Magnetogenetics: remote non-invasive magnetic activation of neuronal activity with a magnetoreceptor

(2015) Xiaoyang Long et al.   Science Bulletin

Optogenetics in Developmental Biology: using light to control ion flux-dependent signals in Xenopus embryos

(2015) Dany Spencer Adams et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions

(2015) Laura N. Vandenberg et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

A dynamic regulatory network explains ParaHox gene control of gut patterning in the sea urchin

(2014) R. Annunziata et al.   DEVELOPMENT

Membrane Potential Bistability in Nonexcitable Cells as Described by Inward and Outward Voltage-Gated Ion Channels

(2014) Javier Cervera et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A linear-encoding model explains the variability of the target morphology in regeneration

(2014) D. Lobo et al.   Journal of the Royal Society Interface

Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo

(2014) Michael Levin   MOLECULAR BIOLOGY OF THE CELL

Bioelectric Signaling Regulates Size in Zebrafish Fins

(2014) Simon Perathoner et al.   PLoS Genetics

Early asymmetric cues triggering the dorsal/ventral gene regulatory network of the sea urchin embryo

(2014) Vincenzo Cavalieri et al.   eLife

Establishment of spatial pattern

(2014) Jonathan Slack   Wiley Interdisciplinary Reviews-Developmental Biology

Metabolic gradients as key regulators in zonation of tumor energy metabolism: A tissue-scale model-based study

(2013) Matthias König et al.   Biotechnology Journal

Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response

(2013) Emma Watson et al.   CELL

Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model

(2013) B. T. Chernet et al.   Disease Models & Mechanisms

Quantifying causal emergence shows that macro can beat micro

(2013) E. P. Hoel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Light-activation of the Archaerhodopsin H+-pump reverses age-dependent loss of vertebrate regeneration: sparking system-level controls in vivo

(2013) D. S. Adams et al.   Biology Open

Transducing Bioelectric Signals into Epigenetic Pathways During Tadpole Tail Regeneration

(2012) Ai-Sun Tseng et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Regulation of Cell Behavior and Tissue Patterning by Bioelectrical Signals: Challenges and Opportunities for Biomedical Engineering

(2012) Michael Levin et al.   Annual Review of Biomedical Engineering

What is Hysteresis?

(2012) K. A. Morris   Applied Mechanics Reviews

Morphogenetic fields in embryogenesis, regeneration, and cancer: Non-local control of complex patterning

(2012) Michael Levin   BIOSYSTEMS

Organ repair and regeneration: An overview

(2012) Joëlle A. Baddour et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Bioelectric signaling regulates head and organ size during planarian regeneration

(2012) W. S. Beane et al.   DEVELOPMENT

Wnt signaling in planarians: new answers to old questions

(2012) Maria Almuedo-Castillo et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The logic of gene regulatory networks in early vertebrate forebrain patterning

(2012) Leonardo Beccari et al.   MECHANISMS OF DEVELOPMENT

Wnt Proteins

(2012) K. Willert et al.   Cold Spring Harbor Perspectives in Biology

Modeling Planarian Regeneration: A Primer for Reverse-Engineering the Worm

(2012) Daniel Lobo et al.   PLoS Computational Biology

Neurally Derived Tissues inXenopus laevisEmbryos Exhibit a Consistent Bioelectrical Left-Right Asymmetry

(2012) Vaibhav P. Pai et al.   Stem Cells International

Network based transcription factor analysis of regenerating axolotl limbs

(2011) Deepali Jhamb et al.   BMC BIOINFORMATICS

A Jump-Start for Planarian Head Regeneration

(2011) Amy K. Sater   CHEMISTRY & BIOLOGY

A Chemical Genetics Approach Reveals H,K-ATPase-Mediated Membrane Voltage Is Required for Planarian Head Regeneration

(2011) Wendy S. Beane et al.   CHEMISTRY & BIOLOGY

Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis

(2011) V. P. Pai et al.   DEVELOPMENT

The Cellular Basis for Animal Regeneration

(2011) Elly M. Tanaka et al.   DEVELOPMENTAL CELL

V-ATPase-dependent ectodermal voltage and ph regionalization are required for craniofacial morphogenesis

(2011) Laura N. Vandenberg et al.   DEVELOPMENTAL DYNAMICS

HDAC Activity Is Required during Xenopus Tail Regeneration

(2011) Ai-Sun Tseng et al.   PLoS One

Investigation of the enzymatic activity of the Na+,K+-ATPase via isothermal titration microcalorimetry

(2010) Raimund Noske et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The ATP-sensitive K+-channel (KATP) controls early left–right patterning in Xenopus and chick embryos

(2010) Sherry Aw et al.   DEVELOPMENTAL BIOLOGY

The planarian flatworm: an in vivo model for stem cell biology and nervous system regeneration

(2010) L. Gentile et al.   Disease Models & Mechanisms

Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway

(2010) D. Blackiston et al.   Disease Models & Mechanisms

Induction of Vertebrate Regeneration by a Transient Sodium Current

(2010) A.-S. Tseng et al.   JOURNAL OF NEUROSCIENCE

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin

(2010) Ligong Chen et al.   Pharmacogenetics and Genomics

Beta-catenin and axis formation in planarians

(2009) Hans Meinhardt   BIOESSAYS

Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration

(2009) Néstor J. Oviedo et al.   DEVELOPMENTAL BIOLOGY

Planarian regeneration: achievements and future directions after 20 years of research

(2009) Emili Salo et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Electrical dimensions in cell science

(2009) C. D. McCaig et al.   JOURNAL OF CELL SCIENCE

Glutamate Transporter Coupling to Na,K-ATPase

(2009) E. M. Rose et al.   JOURNAL OF NEUROSCIENCE

Role of Membrane Potential in the Regulation of Cell Proliferation and Differentiation

(2009) Sarah Sundelacruz et al.   Stem Cell Reviews and Reports

Gradients in Planarian Regeneration and Homeostasis

(2009) T. Adell et al.   Cold Spring Harbor Perspectives in Biology

Using Chemistry and Microfluidics To Understand the Spatial Dynamics of Complex Biological Networks

(2008) Christian J. Kastrup et al.   ACCOUNTS OF CHEMICAL RESEARCH

Slicing across Kingdoms: Regeneration in Plants and Animals

(2008) Kenneth D. Birnbaum et al.   CELL

Metabolic Gradients: A New System for Old Questions

(2008) Neil W. Blackstone   CURRENT BIOLOGY

How ATP Inhibits the Open KATPChannel

(2008) Tim J. Craig et al.   JOURNAL OF GENERAL PHYSIOLOGY

Binding of spermine and ifenprodil to a purified, soluble regulatory domain of theN-methyl-d-aspartate receptor

(2008) Xia Han et al.   JOURNAL OF NEUROCHEMISTRY

On the voltage-dependent Ca2+block of serotonin 5-HT3receptors: a critical role of intracellular phosphates

(2008) Yoav Noam et al.   JOURNAL OF PHYSIOLOGY-LONDON

Modelling and analysis of gene regulatory networks

(2008) Guy Karlebach et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane Potential Controls Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells

(2008) Sarah Sundelacruz et al.   PLoS One