A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition
Authors
Keywords
-
Journal
Journal of the Royal Society Interface
Volume 14, Issue 134, Pages 20170320
Publisher
The Royal Society
Online
2017-09-20
DOI
10.1098/rsif.2017.0320
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- 3D hybrid modelling of vascular network formation
- (2017) Holger Perfahl et al. JOURNAL OF THEORETICAL BIOLOGY
- Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy
- (2016) R. Serre et al. CANCER RESEARCH
- Employing dynamical computational models for personalizing cancer immunotherapy
- (2016) Zvia Agur et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- A cancer treatment based on synergy between anti-angiogenic and immune cell therapies
- (2016) Luis Soto-Ortiz et al. JOURNAL OF THEORETICAL BIOLOGY
- A mathematical prognosis model for pancreatic cancer patients receiving immunotherapy
- (2016) Xuefang Li et al. JOURNAL OF THEORETICAL BIOLOGY
- Mathematical model of tumor–immune surveillance
- (2016) Khaphetsi Joseph Mahasa et al. JOURNAL OF THEORETICAL BIOLOGY
- Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial
- (2016) Padmanee Sharma et al. LANCET ONCOLOGY
- Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis
- (2016) Kerri-Ann Norton et al. Scientific Reports
- Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies
- (2015) M. Ilie et al. ANNALS OF ONCOLOGY
- Modes of cancer cell invasion and the role of the microenvironment
- (2015) Andrew G Clark et al. CURRENT OPINION IN CELL BIOLOGY
- Toward understanding and exploiting tumor heterogeneity
- (2015) Ash A Alizadeh et al. NATURE MEDICINE
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
- (2015) Hossein Borghaei et al. NEW ENGLAND JOURNAL OF MEDICINE
- Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
- (2015) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Multicompartment Mathematical Model of Cancer Stem Cell-Driven Tumor Growth Dynamics
- (2014) Suzanne L. Weekes et al. BULLETIN OF MATHEMATICAL BIOLOGY
- Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy
- (2014) J. M. Taube et al. CLINICAL CANCER RESEARCH
- PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment
- (2014) Dimitrios Mathios et al. JOURNAL OF NEURO-ONCOLOGY
- Modeling cancer-immune responses to therapy
- (2014) L. G. dePillis et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- An agent-based model of cancer stem cell initiated avascular tumour growth and metastasis: the effect of seeding frequency and location
- (2014) K.-A. Norton et al. Journal of the Royal Society Interface
- Unleashing the immune system: PD-1 and PD-Ls in the pre-treatment tumor microenvironment and correlation with response to PD-1/PD-L1 blockade
- (2014) Janis M Taube OncoImmunology
- The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models
- (2013) Sirus Palsson et al. BMC Systems Biology
- Evidence for a Role of the PD-1:PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma
- (2013) S. Lyford-Pike et al. CANCER RESEARCH
- PD-L1 Expression in the Merkel Cell Carcinoma Microenvironment: Association with Inflammation, Merkel Cell Polyomavirus, and Overall Survival
- (2013) E. J. Lipson et al. Cancer Immunology Research
- Evasion of tumours from the control of the immune system: consequences of brief encounters
- (2012) Mohannad Al-Tameemi et al. Biology Direct
- Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): From microscopic measurements to macroscopic predictions of clinical progression
- (2012) Paul Macklin et al. JOURNAL OF THEORETICAL BIOLOGY
- Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
- (2012) J. M. Taube et al. Science Translational Medicine
- Immunoediting: evidence of the multifaceted role of the immune system in self-metastatic tumor growth
- (2012) Heiko Enderling et al. Theoretical Biology and Medical Modelling
- Disruption of a Quorum Sensing mechanism triggers tumorigenesis: a simple discrete model corroborated by experiments in mammary cancer stem cells
- (2010) Zvia Agur et al. Biology Direct
- The promoting role of a tumour-secreted chemorepellent in self-metastatic tumour progression
- (2010) H. Enderling et al. MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA
- Cross-scale, cross-pathway evaluation using an agent-based non-small cell lung cancer model
- (2009) Zhihui Wang et al. BIOINFORMATICS
- Migration rules: tumours are conglomerates of self-metastases
- (2009) H Enderling et al. BRITISH JOURNAL OF CANCER
- Paradoxical Dependencies of Tumor Dormancy and Progression on Basic Cell Kinetics
- (2009) H. Enderling et al. CANCER RESEARCH
- Evolution of cell motility in an individual-based model of tumour growth
- (2009) P. Gerlee et al. JOURNAL OF THEORETICAL BIOLOGY
- A 2D mechanistic model of breast ductal carcinoma in situ (DCIS) morphology and progression
- (2009) Kerri-Ann Norton et al. JOURNAL OF THEORETICAL BIOLOGY
- Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging
- (2009) Benjamin J Vakoc et al. NATURE MEDICINE
- A hybrid cellular automaton model of clonal evolution in cancer: The emergence of the glycolytic phenotype
- (2008) P. Gerlee et al. JOURNAL OF THEORETICAL BIOLOGY
- A methodology for performing global uncertainty and sensitivity analysis in systems biology
- (2008) Simeone Marino et al. JOURNAL OF THEORETICAL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More