Uncovering the underlying mechanism of cancer tumorigenesis and development under an immune microenvironment from global quantification of the landscape

Cancer Immunotherapy Booster

(2016)   CELL

Physical mechanism of mind changes and tradeoffs among speed, accuracy, and energy cost in brain decision making: Landscape, flux, and path perspectives

(2016) Han Yan et al.   Chinese Physics B

The urgent need to recover MHC class I in cancers for effective immunotherapy

(2016) Federico Garrido et al.   CURRENT OPINION IN IMMUNOLOGY

Neutrophils in the Tumor Microenvironment

(2016) Davalyn R. Powell et al.   TRENDS IN IMMUNOLOGY

Targeting breast cancer stem cells by dendritic cell vaccination in humanized mice with breast tumor: preliminary results

(2016) Phuc Van Pham et al.   OncoTargets and Therapy

Landscape and flux theory of non-equilibrium dynamical systems with application to biology

(2015) Jin Wang   ADVANCES IN PHYSICS

Quantifying the Landscape for Development and Cancer from a Core Cancer Stem Cell Circuit

(2015) C. Li et al.   CANCER RESEARCH

Immunosuppression associated with chronic inflammation in the tumor microenvironment

(2015) Dingzhi Wang et al.   CARCINOGENESIS

Treg(s) in Cancer: Friends or Foe?

(2015) Dominik Wolf et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis

(2015) Jo Marie Tran Janco et al.   JOURNAL OF IMMUNOLOGY

Dendritic-cell vaccines on the move

(2015) Rachel Lubong Sabado et al.   NATURE

Induction of T-cell memory by a dendritic cell vaccine: a computational model

(2014) Francesco Pappalardo et al.   BIOINFORMATICS

Periodic and chaotic oscillations in a tumor and immune system interaction model with three delays

(2014) Ping Bi et al.   CHAOS

Phenotypes, accumulation, and functions of myeloid-derived suppressor cells and associated treatment strategies in cancer patients

(2014) Jingwei Jiang et al.   HUMAN IMMUNOLOGY

Quantifying the underlying landscape and paths of cancer

(2014) C. Li et al.   Journal of the Royal Society Interface

The Potential and Flux Landscape Theory of Ecology

(2014) Li Xu et al.   PLoS One

Stem cell differentiation as a many-body problem

(2014) B. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling putative therapeutic implications of exosome exchange between tumor and immune cells

(2014) Mingyang Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Landscape and flux reveal a new global view and physical quantification of mammalian cell cycle

(2014) Chunhe Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NK cell-based immunotherapy for malignant diseases

(2013) Min Cheng et al.   Cellular & Molecular Immunology

Correlation between Th17 cells and tumor microenvironment

(2013) Wenhui Qi et al.   CELLULAR IMMUNOLOGY

Myeloid-derived suppressor cells in cancer: recent progress and prospects

(2013) Yazan S Khaled et al.   IMMUNOLOGY AND CELL BIOLOGY

Quantifying Waddington landscapes and paths of non-adiabatic cell fate decisions for differentiation, reprogramming and transdifferentiation

(2013) C. Li et al.   Journal of the Royal Society Interface

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

The immune network in pancreatic cancer development and progression

(2013) S M Wörmann et al.   ONCOGENE

Nonequilibrium landscape theory of neural networks

(2013) H. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mathematical models of immune-induced cancer dormancy and the emergence of immune evasion

(2013) K. P. Wilkie et al.   Interface Focus

Quantifying Cell Fate Decisions for Differentiation and Reprogramming of a Human Stem Cell Network: Landscape and Biological Paths

(2013) Chunhe Li et al.   PLoS Computational Biology

Dendritic Cells in the Cancer Microenvironment

(2013) Yang Ma et al.   Journal of Cancer

Immature, Semi-Mature, and Fully Mature Dendritic Cells: Toward a DC-Cancer Cells Interface That Augments Anticancer Immunity

(2013) Aleksandra M. Dudek et al.   Frontiers in Immunology

Interleukin-12 inhibits the survival of human colon cancer stem cells in vitro and their tumor initiating capacity in mice

(2012) Xiao-ling Yin et al.   CANCER LETTERS

Anti-cancer versus cancer-promoting effects of the interleukin-17-producing T helper cells

(2012) Nasr Y.A. Hemdan   IMMUNOLOGY LETTERS

Dendritic cells and their role in tumor immunosurveillance

(2012) Marius Strioga et al.   Innate Immunity

Tumor associated macrophages and neutrophils in tumor progression

(2012) Maria R. Galdiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The potential and flux landscape theory of evolution

(2012) Feng Zhang et al.   JOURNAL OF CHEMICAL PHYSICS

Delay-induced oscillatory dynamics in humoral mediated immune response with two time delays

(2012) Shiferaw Feyissa et al.   NONLINEAR ANALYSIS-REAL WORLD APPLICATIONS

Landscape Topography Determines Global Stability and Robustness of a Metabolic Network

(2012) Chunhe Li et al.   ACS Synthetic Biology

Interleukin-10 Ablation Promotes Tumor Development, Growth, and Metastasis

(2011) T. Tanikawa et al.   CANCER RESEARCH

Th17 cells in cancer: help or hindrance?

(2011) Cailin Moira Wilke et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction

(2011) Bernhard Mlecnik et al.   JOURNAL OF CLINICAL ONCOLOGY

Quantifying the Waddington landscape and biological paths for development and differentiation

(2011) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions Between the Immune System and Cancer: A Brief Review of Non-spatial Mathematical Models

(2010) Raluca Eftimie et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Potential and flux landscapes quantify the stability and robustness of budding yeast cell cycle network

(2010) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delay-induced oscillatory dynamics of tumour–immune system interaction

(2009) Alberto d’Onofrio et al.   MATHEMATICAL AND COMPUTER MODELLING

Potential landscape and flux framework of nonequilibrium networks: Robustness, dissipation, and coherence of biochemical oscillations

(2008) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsic noise, dissipation cost, and robustness of cellular networks: The underlying energy landscape of MAPK signal transduction

(2008) S. Lapidus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells and cytokines in immune rejection of cancer

(2007) M FERRANTINI et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The role of dendritic cells in cytotoxic immune response regulation in ovarian cancer micro-environment

(2007) Iwona Wertel   Frontiers in Bioscience-Landmark

Oscillations and bistability in the dynamics of cytotoxic reactions mediated by the response of immune cells to solid tumours

(2007) O. Lejeune et al.   MATHEMATICAL AND COMPUTER MODELLING