Naloxegol: A Review of Its Use in Patients with Opioid-Induced Constipation

Emerging treatments in neurogastroenterology: a multidisciplinary working group consensus statement on opioid-induced constipation

(2015) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Randomised clinical trial: the long-term safety and tolerability of naloxegol in patients with pain and opioid-induced constipation

(2014) L. Webster et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The effects of mild or moderate hepatic impairment on the pharmacokinetics, safety, and tolerability of naloxegol

(2014) Khanh Bui et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Naloxegol for Opioid-Induced Constipation in Patients with Noncancer Pain

(2014) William D. Chey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the Effect of Naloxegol on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled Crossover Thorough QT/QTc Study in Healthy Volunteers

(2013) Christer Gottfridsson et al.   CLINICAL THERAPEUTICS

A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation

(2013) Lynn Webster et al.   PAIN

Opioid-Induced Bowel Dysfunction

(2012) Christina Brock et al.   DRUGS

(210) Results from a phase I, double-blind, randomized, placebo-controlled, multiple-dose study evaluating the safety, tolerability, and pharmacokinetics of oral doses of NKTR-118

(2008) D. Sahner et al.   JOURNAL OF PAIN