Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

PALB2,CHEK2andATMrare variants and cancer risk: data from COGS

(2016) Melissa C Southey et al.   JOURNAL OF MEDICAL GENETICS

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

(2016) Alison M Dunning et al.   NATURE GENETICS

Counselling framework for moderate-penetrance cancer-susceptibility mutations

(2016) Nadine Tung et al.   Nature Reviews Clinical Oncology

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci

(2015) A. Amin Al Olama et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

(2015) Karoline B Kuchenbaecker et al.   NATURE GENETICS

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

(2015) Kyriaki Michailidou et al.   NATURE GENETICS

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

(2014) Wei-Yu Lin et al.   HUMAN MOLECULAR GENETICS

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

(2014) Maya Ghoussaini et al.   Nature Communications

Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers

(2013) Juliet D. French et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1

(2013) Kerstin B. Meyer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Incorporating genomics into breast and prostate cancer screening: assessing the implications

(2013) Susmita Chowdhury et al.   GENETICS IN MEDICINE

Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE

(2013) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

(2013) Stig E Bojesen et al.   NATURE GENETICS

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

(2013) Kyriaki Michailidou et al.   NATURE GENETICS

Familial breast cancer: summary of updated NICE guidance

(2013) D. G. Evans et al.   BMJ-British Medical Journal

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

(2013) Fergus J. Couch et al.   PLoS Genetics

Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk

(2013) Mia M. Gaudet et al.   PLoS Genetics

Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

(2012) N. Mavaddat et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status

(2012) Anika Hüsing et al.   JOURNAL OF MEDICAL GENETICS

Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriers

(2011) R. L. Milne et al.   ANNALS OF ONCOLOGY

Clinical Management of Hereditary Breast Cancer Syndromes

(2011) Amy S. Clark et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

(2010) A. C. Antoniou et al.   CANCER RESEARCH

Uptake of Risk-Reducing Surgery in Unaffected Women at High Risk of Breast and Ovarian Cancer Is Risk, Age, and Time Dependent

(2009) D. G. R. Evans et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers

(2009) T. R. Rebbeck et al.   JNCI-Journal of the National Cancer Institute

Increased cardiovascular mortality after early bilateral oophorectomy

(2009) Cathleen M. Rivera et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Increased Mortality for Neurological and Mental Diseases following Early Bilateral Oophorectomy

(2009) Cathleen M. Rivera et al.   NEUROEPIDEMIOLOGY

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

(2008) A C Antoniou et al.   BRITISH JOURNAL OF CANCER