Local Immunotherapy of Cancer: Innovative Approaches to Harnessing Tumor-Specific Immune Responses
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Local Immunotherapy of Cancer: Innovative Approaches to Harnessing Tumor-Specific Immune Responses
Authors
Keywords
-
Journal
JNCI-Journal of the National Cancer Institute
Volume 109, Issue 12, Pages -
Publisher
Oxford University Press (OUP)
Online
2017-04-28
DOI
10.1093/jnci/djx097
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Results of a phase II, open-label, non-comparative study of intralesional PV-10 followed by radiotherapy for the treatment of in-transit or metastatic melanoma
- (2017) Matthew Foote et al. JOURNAL OF SURGICAL ONCOLOGY
- Intralymphatic Injection of Autoantigen in Type 1 Diabetes
- (2017) Johnny Ludvigsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Combination immunotherapy: a road map
- (2017) Patrick A. Ott et al. Journal for ImmunoTherapy of Cancer
- OPTiM: A randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma.
- (2017) Robert Hans Ingemar Andtbacka et al. JOURNAL OF CLINICAL ONCOLOGY
- Patterns of Clinical Response with Talimogene Laherparepvec (T-VEC) in Patients with Melanoma Treated in the OPTiM Phase III Clinical Trial
- (2016) Robert H. I. Andtbacka et al. ANNALS OF SURGICAL ONCOLOGY
- Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity
- (2016) Kalijn F. Bol et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The host STING pathway at the interface of cancer and immunity
- (2016) Leticia Corrales et al. JOURNAL OF CLINICAL INVESTIGATION
- Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma
- (2016) Igor Puzanov et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma
- (2016) Lee A. Wheeler et al. NEURO-ONCOLOGY
- Fulminant Myocarditis with Combination Immune Checkpoint Blockade
- (2016) Douglas B. Johnson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antitumor dendritic cell–based vaccines: lessons from 20 years of clinical trials and future perspectives
- (2016) João Constantino et al. Translational Research
- Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the Phase III OPTiM trial
- (2016) Kevin Harrington et al. OncoTargets and Therapy
- A phase I study of intratumoral ipilimumab and interleukin-2 in patients with advanced melanoma
- (2016) Abhijit Ray et al. Oncotarget
- Combinational Immunotherapy with Allo-DRibble Vaccines and Anti-OX40 Co-Stimulation Leads to Generation of Cross-Reactive Effector T Cells and Tumor Regression
- (2016) Guangjie Yu et al. Scientific Reports
- Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study
- (2015) Riccardo Danielli et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma
- (2015) Laura K. Aguilar et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN
- (2015) Burcu Temizoz et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer
- (2015) Kevin C. Conlon et al. JOURNAL OF CLINICAL ONCOLOGY
- Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center
- (2015) Troy Z. Horvat et al. JOURNAL OF CLINICAL ONCOLOGY
- Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma
- (2015) Robert H.I. Andtbacka et al. JOURNAL OF CLINICAL ONCOLOGY
- Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: results from a phase I trial in advanced melanoma
- (2015) Carmela Rozera et al. Journal of Translational Medicine
- Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
- (2015) Christina Twyman-Saint Victor et al. NATURE
- Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
- (2015) Hossein Borghaei et al. NEW ENGLAND JOURNAL OF MEDICINE
- Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
- (2015) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immature myeloid cells and tolerogenic cytokine profile in lung adenocarcinoma metastatic lymph nodes assessed by endobronchial ultrasound
- (2015) Antonio Bugalho et al. TUMOR BIOLOGY
- Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients
- (2015) Kalijn F Bol et al. OncoImmunology
- Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma
- (2014) John F. Thompson et al. ANNALS OF SURGICAL ONCOLOGY
- Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma
- (2014) Arne Kolstad et al. BLOOD
- Results of a Randomized Phase I Gene Therapy Clinical Trial of Nononcolytic Fowlpox Viruses Encoding T Cell Costimulatory Molecules
- (2014) Howard L. Kaufman et al. HUMAN GENE THERAPY
- Microenvironment of Tumor-Draining Lymph Nodes: Opportunities for Liposome-Based Targeted Therapy
- (2014) Siddarth Chandrasekaran et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Adenoviral-Based Immunotherapy Provides Local Disease Control in an Orthotopic Murine Model of Esophageal Cancer
- (2014) Jon G. Quatromoni et al. JOURNAL OF IMMUNOTHERAPY
- Intralesional Treatment of Stage III Metastatic Melanoma Patients with L19-IL2 Results in Sustained Clinical and Systemic Immunologic Responses
- (2014) B. Weide et al. Cancer Immunology Research
- Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo
- (2014) Linda C Sandin et al. OncoImmunology
- The role of intratumoral and systemic IL-6 in breast cancer
- (2013) Christine Dethlefsen et al. BREAST CANCER RESEARCH AND TREATMENT
- Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab
- (2013) Jeffrey S. Weber et al. CANCER
- Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity
- (2013) B. Kwong et al. CANCER RESEARCH
- OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients
- (2013) B. D. Curti et al. CANCER RESEARCH
- Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors
- (2013) J. Duraiswamy et al. CANCER RESEARCH
- Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-Cell-Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects
- (2013) M. F. Fransen et al. CLINICAL CANCER RESEARCH
- Differential CTLA-4 expression in human CD4+ versus CD8+ T cells is associated with increased NFAT1 and inhibition of CD4+ proliferation
- (2013) D V Chan et al. GENES AND IMMUNITY
- Dendritic-Cell-Based Therapeutic Cancer Vaccines
- (2013) Karolina Palucka et al. IMMUNITY
- Depleting tumor-specific Tregs at a single site eradicates disseminated tumors
- (2013) Aurélien Marabelle et al. JOURNAL OF CLINICAL INVESTIGATION
- Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell–mediated glioma rejection
- (2013) Johannes vom Berg et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Immune cell profile of sentinel lymph nodes in patients with malignant melanoma – FOXP3+ cell density in cases with positive sentinel node status is associated with unfavorable clinical outcome
- (2013) Anita Mohos et al. Journal of Translational Medicine
- Clinical significance of the frequency of regulatory T cells in regional lymph node lymphocytes as a prognostic factor for non-small-cell lung cancer
- (2013) Takeshi Hanagiri et al. LUNG CANCER
- Nivolumab plus Ipilimumab in Advanced Melanoma
- (2013) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Local immunomodulation for cancer therapy: Providing treatment where needed
- (2013) Marieke Fransen et al. OncoImmunology
- Human Langerhans cells are immature in melanoma sentinel lymph nodes
- (2012) G. Gerlini et al. BLOOD
- Cellular and cytokine-dependent immunosuppressive mechanisms of grm1-transgenic murine melanoma
- (2012) Miriam Alb et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Gene Immunotherapy of Chronic Lymphocytic Leukemia: A Phase I Study of Intranodally Injected Adenovirus Expressing a Chimeric CD154 Molecule
- (2012) J. E. Castro et al. CANCER RESEARCH
- Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness
- (2012) Jarrod D Predina et al. Journal of Hematology & Oncology
- Intratumoral hu14.18-IL-2 (IC) Induces Local and Systemic Antitumor Effects That Involve Both Activated T and NK Cells As Well As Enhanced IC Retention
- (2012) R. K. Yang et al. JOURNAL OF IMMUNOLOGY
- Increase of regulatory T cells in metastatic stage and CTLA-4 over expression in lymphocytes of patients with non-small cell lung cancer (NSCLC)
- (2012) Nasrollah Erfani et al. LUNG CANCER
- Immune response in melanoma: an in-depth analysis of the primary tumor and corresponding sentinel lymph node
- (2012) Michelle W Ma et al. MODERN PATHOLOGY
- Oncolytic virotherapy
- (2012) Stephen J Russell et al. NATURE BIOTECHNOLOGY
- Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
- (2012) Jason Park et al. NATURE MATERIALS
- B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
- (2011) J. N. Kochenderfer et al. BLOOD
- Local and systemic antitumor effect of intratumoral and peritumoral IL-12 electrogene therapy on murine sarcoma
- (2011) Darja Pavlin et al. CANCER BIOLOGY & THERAPY
- Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models
- (2011) J D Predina et al. CANCER GENE THERAPY
- Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses
- (2011) Connie Jackaman et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Viral Vector-Based Therapeutic Cancer Vaccines
- (2011) Cecilia Larocca et al. CANCER JOURNAL
- Intratumoral injection of interleukin-2 augments the local and abscopal effects of radiotherapy in murine rectal cancer
- (2011) Koji Yasuda et al. CANCER SCIENCE
- Route of Administration Modulates the Induction of Dendritic Cell Vaccine-Induced Antigen-Specific T Cells in Advanced Melanoma Patients
- (2011) W. J. Lesterhuis et al. CLINICAL CANCER RESEARCH
- Combination of External Beam Radiotherapy (EBRT) With Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients
- (2011) Steven E. Finkelstein et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Safety and Efficacy of Combination Immunotherapy With Interferon Alfa-2b and Tremelimumab in Patients With Stage IV Melanoma
- (2011) Ahmad A. Tarhini et al. JOURNAL OF CLINICAL ONCOLOGY
- Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients
- (2010) Qing Yi et al. BRITISH JOURNAL OF HAEMATOLOGY
- Survival after intratumoral interleukin-2 treatment of 72 melanoma patients and response upon the first chemotherapy during follow-up
- (2010) Benjamin Weide et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Intranodal Vaccination with Naked Antigen-Encoding RNA Elicits Potent Prophylactic and Therapeutic Antitumoral Immunity
- (2010) S. Kreiter et al. CANCER RESEARCH
- Accumulation of Foxp3+ T Regulatory Cells in Draining Lymph Nodes Correlates with Disease Progression and Immune Suppression in Colorectal Cancer Patients
- (2010) L. Deng et al. CLINICAL CANCER RESEARCH
- Analysis of Dendritic Cells in Sentinel Lymph Nodes of Patients With Endometrial and Patients With Cervical Cancers
- (2010) P. Pelin Kara et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study
- (2010) Joshua D. Brody et al. JOURNAL OF CLINICAL ONCOLOGY
- High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation
- (2010) Chuan-Yong Mu et al. MEDICAL ONCOLOGY
- Treatment of Chronic Lymphocytic Leukemia With Genetically Targeted Autologous T Cells: Case Report of an Unforeseen Adverse Event in a Phase I Clinical Trial
- (2010) Renier Brentjens et al. MOLECULAR THERAPY
- Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
- (2010) Richard A Morgan et al. MOLECULAR THERAPY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer
- (2009) Aaron S Mansfield et al. BMC CANCER
- Intratumoral delivery of encapsulated IL-12, IL-18 and TNF-α in a model of metastatic breast cancer
- (2009) Michael S. Sabel et al. BREAST CANCER RESEARCH AND TREATMENT
- Therapeutic injection of C-class CpG ODN in draining lymph node area induces potent activation of immune cells and rejection of established breast cancer in mice
- (2009) Liang Yang et al. CLINICAL IMMUNOLOGY
- The significance of OX40 and OX40L to T-cell biology and immune disease
- (2009) Michael Croft et al. IMMUNOLOGICAL REVIEWS
- Tumour-derived prostaglandin E2and transforming growth factor-β synergize to inhibit plasmacytoid dendritic cell-derived interferon-α
- (2009) Isabelle Bekeredjian-Ding et al. IMMUNOLOGY
- Tumor Regulatory T Cells Potently Abrogate Antitumor Immunity
- (2009) Zuqiang Liu et al. JOURNAL OF IMMUNOLOGY
- T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy
- (2008) R. Houot et al. BLOOD
- OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection
- (2008) Silvia Piconese et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CTLA-4 Control over Foxp3+ Regulatory T Cell Function
- (2008) K. Wing et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now