Are PEGylated liposomes better than conventional liposomes? A special case for vincristine

Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation

(2014) Robert Hennig et al.   JOURNAL OF CONTROLLED RELEASE

Phase II Study of Vincristine Sulfate Liposome Injection (Marqibo) and Rituximab for Patients With Relapsed and Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma in Need of Palliative Therapy

(2013) Lawrence D. Kaplan et al.   Clinical Lymphoma Myeloma & Leukemia

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

High-Dose Vincristine Sulfate Liposome Injection for Advanced, Relapsed, and Refractory Adult Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia

(2012) Susan O'Brien et al.   JOURNAL OF CLINICAL ONCOLOGY

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Development of Pegylated Liposomal Vincristine Using Novel Sulfobutyl Ether Cyclodextrin Gradient: Is Improved Drug Retention Sufficient to Surpass DSPE–PEG-Induced Drug Leakage?

(2011) Jingxia Cui et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Phase 1 multicenter study of vincristine sulfate liposomes injection and dexamethasone in adults with relapsed or refractory acute lymphoblastic leukemia

(2009) Deborah A. Thomas et al.   CANCER

Vincristine sulfate liposomes injection (Marqibo) in heavily pretreated patients with refractory aggressive non-Hodgkin lymphoma

(2009) M. A. Rodriguez et al.   CANCER

Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine

(2009) Charles O. Noble et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Recent Advances in Cancer Therapy: An Overview

(2009) A. Urruticoechea et al.   CURRENT PHARMACEUTICAL DESIGN

Tumor targeting of vincristine by mBAFF-modified PEG liposomes in B lymphoma cells

(2008) Li Zhang et al.   CANCER LETTERS

A pilot study with vincristine sulfate liposome infusion in patients with metastatic melanoma

(2008) Agop Y. Bedikian et al.   MELANOMA RESEARCH