Article
Infectious Diseases
Wendy Thompson, Jonathan Sandoe, Sue Pavitt, Tanya Walsh, Lucie Byrne-Davis
Summary: This research aims to co-develop an antibiotic stewardship tool for dentistry, focusing on optimizing antibiotic prescribing through shared decision-making. The tool design is informed by behavior change techniques and on-site research, with multiple tests confirming its acceptability to dentists and patients, showing potential to reduce unnecessary antibiotic prescribing in dental contexts globally.
Article
Geriatrics & Gerontology
E. S. T. H. E. R. A. R. HARTMAN, W. I. M. G. GROEN, S. I. L. J. E. R. E. B. E. K. K. A. HELTVEIT-OLSEN, M. O. R. T. E. N. LINDBAEK, S. I. G. U. R. D. HOYE, PAR-DANIEL SUNDVALL, I. N. G. M. A. R. I. E. SKOGLUND, E. G. I. L. L. SNAEBJORNSSON ARNLJOTS, R. O. N. N. Y. GUNNARSSON, A. N. N. A. KOWALCZYK, M. A. C. I. E. K. GODYCKI-CWIRKO, K. A. T. A. R. Z. Y. N. A. KOSIEK, T. A. M. A. R. A. N. PLATTEEL, A. L. M. A. C. VAN DE POL, T. H. E. O. J. M. VERHEIJ, A. N. N. E. L. I. E. A. MONNIER, C. E. E. S. M. P. M. HERTOGH
Summary: This study explores the factors contributing to antibiotic prescribing for suspected urinary tract infections (UTIs) in frail older adults. By examining clinical complexity, diagnostic factors, knowledge and attitudes, communication, and the context and organization of care, an overarching model is developed to guide the development of antibiotic stewardship interventions for UTIs in this population.
Article
Immunology
Derek R. MacFadden, Colleen Maxwell, Dawn Bowdish, Susan Bronskill, James Brooks, Kevin Brown, Lori L. Burrows, Anna Clarke, Bradley Langford, Elizabeth Leung, Valerie Leung, Doug Manuel, Allison McGeer, Sharmistha Mishra, Andrew M. Morris, Caroline Nott, Sumit Raybardhan, Mia Sapin, Kevin L. Schwartz, Miranda So, Jean-Paul R. Soucy, Nick Daneman
Summary: Antibiotic use is common among patients diagnosed with SARS-CoV-2. However, those who have completed the primary COVID-19 vaccination series have significantly reduced antibiotic use.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Immunology
Marion Elligsen, Ruxandra Pinto, Jerome A. Leis, Sandra A. N. Walker, Nick Daneman, Derek R. MacFadden
Summary: This study demonstrated that an AMS intervention, based on individualized predictive models for resistance, can influence empiric antibiotic selections for GN bacteremia to facilitate early de-escalation of therapy without compromising adequacy of antibiotic coverage.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Twisha S. Patel, Olivia L. McGovern, Garrett Mahon, Hanako Osuka, Icaro Boszczowski, Jose M. Munita, Maria Isabel Garzon, Matias C. Salomao, Giovanna Marssola, Bruno M. Tavares, Debora B. Francisco, Alessandra P. A. Gurgel, Tiago Arantes, Andrea Bori, Cassimiro Nogueira, Anne Peters, Maria Spencer, Cristian Orellana, Mario Barbe, Constanza Lopez, Stacie Stender, Fernanda C. Lessa
Summary: An ecological evaluation was conducted to assess antibiotic use among inpatients in Argentina, Brazil, and Chile during the COVID-19 pandemic. The study showed a substantial increase in antibiotic use compared to the pre-pandemic period. This highlights the importance of maintaining or strengthening antibiotic stewardship activities during pandemic or emergency healthcare facility responses.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Immunology
Dipesh Solanky, Olivia L. McGovern, Jonathan R. Edwards, Garrett Mahon, Twisha S. Patel, Fernanda C. Lessa, Lauri A. Hicks, Payal K. Patel
Summary: During the COVID-19 pandemic in Brazil, there was a significant increase in the prescription of azithromycin for respiratory infections, with patient age and sex being independent predictors of this change. General practitioners and gynecologists were the most common prescribers. The impact of the pandemic on outpatient antibiotic prescribing in Brazil is not well-described.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Public, Environmental & Occupational Health
Andrea M. Kurasz, Glenn E. Smith, Rosie E. Curiel, Warren W. Barker, Raquel C. Behar, Alexandra Ramirez, Melissa J. Armstrong
Summary: This study aimed to investigate the types of values that culturally diverse older adults incorporate in medical decision making. The results showed that individual factors, familial/cultural beliefs and expectations, balancing risks and benefits, receiving decisional support, and considering values other than their own all influence the medical decisions of older adults. Clinicians should take the time to understand and reassess the various types of values of older adults.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Geriatrics & Gerontology
Yunjiao Chen, Jie Xu, Cai Xing
Summary: This study explored the influence of aging, framing, and social distance on decision making in the medical domain. The results indicated that social distance moderated framing effects in older adults, as they were less inclined to take risky options when making decisions for strangers. These findings highlight a potential way to improve older adults' medical decision-making quality.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2023)
Article
Gastroenterology & Hepatology
Nancy L. Schoenborn, Craig E. Pollack, Samir Gupta, Cynthia M. Boyd
Summary: This study examined physicians' decision-making on surveillance colonoscopies in older adults and found that recommendations varied depending on patient age, health status, and prior adenoma risk. Some physicians reported uncertainty regarding the balance of benefits and harms of surveillance in older adults and expressed the need for decision support tools. Further research is needed to evaluate the benefits and harms of surveillance colonoscopy in older adults and provide decision support tools to assist physicians and patients in making informed decisions.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Public, Environmental & Occupational Health
Eileen J. Carter, Jingjing Shang, Maureen George, Christine DeForge, Grace Mackson, Zachary J. Palace, Patricia Stone
Summary: Antibiotics are commonly used in nursing homes, but little is known about the perceptions and experiences of NH residents regarding antibiotic use. This qualitative study conducted interviews with NH residents and identified four themes: perceived benefits and risks, information needs, approaches to address information needs, and resident involvement in decision making. Future efforts should focus on addressing the unmet information needs of NH residents to improve collaborative decision making and antibiotic use.
AMERICAN JOURNAL OF INFECTION CONTROL
(2023)
Review
Geriatrics & Gerontology
Eva Heilmann, Claudia Gregoriano, Djillali Annane, Konrad Reinhart, Lila Bouadma, Michel Wolff, Jean Chastre, Charles-Edouard Luyt, Florence Tubach, Angela R. Branche, Matthias Briel, Mirjam Christ-Crain, Tobias Welte, Caspar Corti, Evelien de Jong, Maarten Nijsten, Dylan W. de Lange, Jos A. H. van Oers, Albertus Beishuizen, Armand R. J. Girbes, Rodrigo O. Deliberato, Stefan Schroeder, Kristina B. Kristoffersen, Nathalie Layios, Pierre Damas, Stella S. S. Lima, Vandack Nobre, Long Wei, Carolina F. Oliveira, Yahya Shehabi, Daiana Stolz, Michael Tamm, Alessia Verduri, Jin-Xiang Wang, Sabine Drevet, Gaetan Gavazzi, Beat Mueller, Philipp Schuetz
Summary: This meta-analysis confirms that PCT-guided antibiotic treatment in older patients significantly reduces antibiotic exposure and does not increase mortality risk, similar to younger patients.
Article
Immunology
Rebekah W. Moehring, Michael E. Yarrington, Angelina E. Davis, April P. Dyer, Melissa D. Johnson, Travis M. Jones, S. Shaefer Spires, Deverick J. Anderson, Daniel J. Sexton, Elizabeth S. Dodds Ashley
Summary: The study established a collaborative, consultative network to support hospital Antimicrobial Stewardship Programs (ASP). Results showed that participating hospitals increased ASP activities over 42 months, leading to a decline in antimicrobial use. There was significant variation in antimicrobial use among different hospitals.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Neurosciences
Preeti Sunderaraman, Yunglin Gazes, Gema Ortiz, Christopher Langfield, Ashley Mensing, Silvia Chapman, Jillian L. Joyce, Adam M. Brickman, Yaakov Stern, Stephanie Cosentino
Summary: Financial decision-making and financial awareness are both crucial for preventing financial mistakes. Our study found that financial decision-making was negatively correlated with the average mean diffusivity of the temporal-parietal and temporal-frontal tracts, while financial awareness was positively correlated with the average mean diffusivity of the right temporal-frontal tract. These preliminary findings support the unique role of right hemisphere temporal connections in supporting financial awareness.
HUMAN BRAIN MAPPING
(2022)
Article
Immunology
Sara Y. Tartof, Lie Hong Chen, Yun Tian, Rong Wei, Theresa Im, Kalvin Yu, Gunter Rieg, Zoe Bider-Canfield, Frances Wong, Harpreet S. Takhar, Lei Qian
Summary: This retrospective cohort study examined the impact of an antibiotic stewardship program (ASP) on antibiotic usage and infection rates of drug-resistant organisms in a healthcare setting. Results showed a decrease in overall antibiotic use post-ASP implementation, but an increase in vancomycin-resistant enterococci infections. The study suggests that successful reduction in antibiotic consumption through ASPs may not necessarily lead to a decrease in antibiotic-resistant infections.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Computer Science, Information Systems
Sayon Dutta, Dustin S. McEvoy, David M. Rubins, Anand S. Dighe, Michael R. Filbin, Chanu Rhee
Summary: A study found that the implementation of clinical decision support (CDS) in the emergency department (ED) led to an increase in blood cultures before intravenous (IV) antibiotics administration, indicating that CDS may improve the process of obtaining blood cultures for ED patients.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2022)