4.8 Article

Design of Wall-Destructive but Membrane-Compatible Solvents

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 139, Issue 45, Pages 16052-16055

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jacs.7b08914

Keywords

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Funding

  1. COI program, ALCA [2100040]
  2. SIP by Japan Science and Technology Agency
  3. Japan Society for the Promotion of Science [15K17867]
  4. Grants-in-Aid for Scientific Research [15K17867] Funding Source: KAKEN

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We report an extremely biocompatible solvent for plant cell walls based on a polar liquid zwitterion that dissolves cellulose, the most recalcitrant component of the plant cell walls. The polar liquid zwitterion does not affect the viability and activity of Escherichia coli, even at high concentrations. We demonstrate conversion of cell walls to ethanol via a starch-like process, namely successive dissolution, hydrolysis and fermentation in the same reaction pot.

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