Article
Hematology
Wen-Jun Tu, Yicheng Xu, Yakun Liu, Jilai Li, Jichen Du, Jizong Zhao
Summary: This study compared the outcomes of acute ischemic stroke patients with minor deficits treated with intravenous thrombolysis (IVT) or routine medical management (MM). The results showed that the IVT group had a higher rate of stroke independent outcome at 3 months compared to the MM group. There was no significant difference in mortality rates between the two groups.
THROMBOSIS AND HAEMOSTASIS
(2023)
Article
Medicine, General & Internal
Marcin Wnuk, Justyna Derbisz, Leszek Drabik, Maciej Malecki, Agnieszka Slowik
Summary: The study demonstrated that fasting normoglycemia after intravenous thrombolysis for acute ischemic stroke is associated with a favorable long-term outcome, and it acts as an independent protective factor specifically for non-diabetic patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Charith Cooray, Michal Karlinski, Adam Kobayashi, Peter Ringleb, Janika Korv, Mary J. Macleod, Anand Dixit, Elsa Azevedo, Christopher Bladin, Niaz Ahmed
Summary: In acute ischemic stroke patients treated with intravenous thrombolysis, those with prestroke disability did not have a significantly increased risk of symptomatic intracerebral hemorrhage or parenchymal hemorrhage. However, they were associated with a higher risk of early mortality compared to patients without prestroke disability.
INTERNATIONAL JOURNAL OF STROKE
(2021)
Review
Clinical Neurology
Bartosz Karaszewski, Adam Wyszomirski, Bartosz Jablonski, David J. Werring, Dominika Tomaka
Summary: Intravenous recombinant tissue plasminogen activator (iv-rtPA) has been used to treat ischemic stroke for 25 years, but there is limited evidence on its efficacy and safety in strokes caused by cerebral small vessel disease (SVD). While results suggest some benefit and safety in this specific subgroup, further research is needed to make definitive recommendations.
TRANSLATIONAL STROKE RESEARCH
(2021)
Article
Clinical Neurology
Gaultier Marnat, Benjamin Gory, Igor Sibon, Maeva Kyheng, Julien Labreuche, Gregoire Boulouis, Jean-Sebastien Liegey, Jildaz Caroff, Francois Eugene, Olivier Naggara, Arturo Consoli, Mikael Mazighi, Benjamin Maier, Sebastien Richard, Christian Denier, Guillaume Turc, Bertrand Lapergue, Romain Bourcier
Summary: This study retrospectively analyzed consecutive patients included in an ongoing observational multicenter registry from January 2015 to September 2020. The study aimed to investigate the outcome after failed mechanical thrombectomy (MT) in patients with large vessel occlusion stroke (LVOS) and identify predictive factors of favorable outcome despite recanalization failure. The results showed that younger age, lower admission National Institutes of Health Stroke Scale (NIHSS), a lower number of MT passes, a lower delta ASPECTS between initial and Day-1 imaging, and stroke etiology were significantly associated with a 90-day favorable outcome.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Nazanin Jalali, Elyar Sadeghi Hokmabadi, Abdoreza Ghoreishi, Payam Sariaslan, Shahram Rafie, Afshin Borhani-Haghighi, Amir Moghadam Ahmadi, Hossein Azin, Alireza Vakilian, Parvin Khalili, Mehdi Farhoudi
Summary: This descriptive research analyzed the vascular territory and treatment outcomes in Iranian intravenous thrombolysis ischemic stroke patients based on data from the SITS registry. The results showed no significant association between vascular territory and mortality, functional independence, or brain hemorrhage occurrence. Age, diabetes, NIHSS score, and admission duration were identified as important predictors of three-month mortality, excellent outcome, and functional independence.
SCIENTIFIC REPORTS
(2023)
Article
Neurosciences
Zheng Ping, Huiyu She, Li Min, Qingke Bai, Qiuyun Lu, Chen Xu
Summary: In this study, machine learning models were used to predict long-term neurological outcomes in patients with ischemic stroke after intravenous thrombolysis. The results showed that patients with higher modified Rankin scores at 3 months had increased systolic pressure, blood glucose, cholesterol, and 7-day NIHSS scores. The random forest model performed relatively better, and similar results were obtained in the external validation dataset. The explainable AI model also identified the risk factors.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Praneeta Konduri, Henk van Voorst, Amber Bucker, Katinka van Kranendonk, Anna Boers, Kilian Treurniet, Olvert Berkhemer, Albert J. Yoo, Wim van Zwam, Robert van Oostenbrugge, Aad van der Lugt, Diederik Dippel, Yvo Roos, Joost Bot, Charles Majoie, Henk Marquering
Summary: This study investigated the association of subacute ischemic lesion evolution with functional outcomes in acute ischemic stroke patients, finding a significant inverse correlation between lesion evolution and favorable functional outcomes. Successful recanalization did not significantly influence this association between lesion evolution and functional outcomes.
Article
Medicine, General & Internal
Gabriel Broocks, Lukas Meyer, Celine Ruppert, Wolfgang Haupt, Tobias D. Faizy, Noel Van Horn, Matthias Bechstein, Helge Kniep, Sarah Elsayed, Andre Kemmling, Ewgenia Barow, Jens Fiehler, Uta Hanning
Summary: This study analyzed the impact of intravenous thrombolytic therapy (IVT) on functional outcome and secondary injury volumes in patients with complete reperfusion after thrombectomy. The results showed that bridging IVT was associated with a lower proportion of functional independence and a higher rate of symptomatic intracerebral hemorrhage (sICH). Multivariable analysis confirmed the independent association of bridging IVT with sICH and edema volume.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Magnus Thoren, Irene Escudero-Martinez, Tomas Andersson, Shih-Yin Chen, Nicole Tsao, Dheeraj Khurana, Simone Beretta, Andre Peeters, Georgios Tsivgoulis, Christine Roffe, Niaz Ahmed
Summary: This study investigated the association between reperfusion and the development of early cerebral edema after stroke thrombectomy. The results showed that successful reperfusion was associated with a lower risk of early cerebral edema. Severe early neurological deficits may weaken the association between reperfusion and lower risk of cerebral edema.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Neuroimaging
Johannes M. Weller, Franziska Dorn, Gabor C. Petzold, Felix J. Bode
Summary: This study aimed to investigate the effect of ongoing intravenous thrombolysis (IVT) during flow restoration in patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (ET). The results showed that ongoing IVT during flow restoration was associated with better functional outcomes at discharge and at 90 days.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
Yongwoo Kim, Marie Luby, Nina-Serena Burkett, Gina Norato, Richard Leigh, Clinton B. Wright, Kyle C. Kern, Amie W. Hsia, John K. Lynch, Malik M. Adil, Lawrence L. Latour
Summary: The presence of an ischemic lesion on FLAIR within 4.5 hours of stroke onset is associated with a reduced likelihood of favorable outcomes 90 days after IV thrombolysis.
CEREBROVASCULAR DISEASES
(2021)
Article
Clinical Neurology
M. Jensen, F. Boutitie, B. Cheng, T. -H. Cho, M. Ebinger, M. Endres, J. B. Fiebach, J. Fiehler, I. Ford, I. Galinovic, A. Konigsberg, J. Puig, P. Roy, A. Wouters, V. Thijs, R. Lemmens, K. W. Muir, N. Nighoghossian, S. Pedraza, C. Z. Simonsen, C. Gerloff, G. Thomalla
Summary: Polypharmacy in stroke patients is associated with worse functional outcomes after intravenous thrombolysis independent of comorbidities. However, polypharmacy does not interact with the beneficial effect of alteplase.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Neurosciences
Zheng Ping, Li Min, Qiuyun Lu, Chen Xu, Qingke Bai
Summary: This study aimed to develop a convenient nomogram for the bedside evaluation of stroke patients with intravenous thrombolysis, predicting neurological outcomes. Through retrospective evaluation of clinical characteristics of stroke patients and comparing predictive abilities using logistic regression models, a nomogram based on baseline NIHSS, blood sugar, blood cholesterol level, and part-and full anterior circulation infarction (OCSP type) was developed.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Audrey C. Leasure, Lindsey R. Kuohn, Kevin N. Vanent, Matthew B. Bevers, W. Taylor Kimberly, Thorsten Steiner, Stephan A. Mayer, Charles C. Matouk, Lauren H. Sansing, Guido J. Falcone, Kevin N. Sheth
Summary: Higher admission IL-6 levels in patients with spontaneous intracerebral hemorrhage are associated with worse 90-day functional outcome, larger ICH volume, and larger perihematomal edema volume.
Article
Clinical Neurology
Klearchos Psychogios, Magoufis Georgios, Apostolos Safouris, Odysseas Kargiotis, Andrikopoulou Athina, Lina Palaiodimou, Maria Chondrogianni, Eleni Bakola, Georgios Tsivgoulis
Summary: Neurovascular sonography serves as a valuable tool for screening and follow-up of dural arteriovenous fistulas (dAVFs) in the transverse sinuses/sigmoid sinuses. This case report presents a rare case of bilateral dAVFs diagnosed through neurovascular ultrasonography, which was subsequently confirmed by further imaging. The findings highlight the importance of neurovascular sonography in the diagnosis of dAVFs in the transverse sinuses/sigmoid sinuses.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Clinical Neurology
Christos S. Katsouras, Michail I. Papafaklis, Sotirios Giannopoulos, Theodoros Karapanayiotides, Georgios Tsivgoulis, Lampros K. Michalis
Summary: Numerous observational studies have shown a decline in cerebro-/cardiovascular admissions during the early phase of the COVID-19 pandemic, but recent studies suggest that the overall decrease is smaller than initially reported. The main cause of this decline is believed to be collateral damage from the COVID-19 outbreak, including the effects of imposed measures such as social distancing and self-isolation. However, there may also be a smaller true decline in CV events due to a lack of triggers associated with acute syndromes. It is important to prepare healthcare systems for a potential increase in CV hospitalizations in the future.
JOURNAL OF CLINICAL NEUROLOGY
(2023)
Editorial Material
Clinical Neurology
Aikaterini Theodorou, Maria Chondrogianni, Eleni Bakola, Georgia Kaloudi, Aikaterini Foska, Smaragdi Michalakakou, Konstantinos Melanis, Georgios P. Paraskevas, Georgios Tsivgoulis
Review
Clinical Neurology
Georgios Tsivgoulis, Lina Palaiodimou, Sokratis Triantafyllou, Martin Koehrmann, Polychronis Dilaveris, Konstantinos Tsioufis, Gkikas Magiorkinis, Christos Krogias, Peter D. Schellinger, Valeria Caso, Maurizio Paciaroni, Mukul Sharma, Robin Lemmens, David J. Gladstone, Tommaso Sanna, Rolf Wachter, Gerasimos Filippatos, Aristeidis H. Katsanos
Summary: This systematic review and meta-analysis examined the preventive effect of prolonged cardiac monitoring on ischemic stroke (IS) among patients. The findings suggest that prolonged cardiac monitoring is associated with a reduced occurrence of IS.
EUROPEAN STROKE JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Jason J. J. Chang, Hooman Fazlalizadeh, Ehsan Dowlati, Matthew Triano, Charles Withington, Daniel R. R. Felbaum, Jeffrey C. C. Mai, Rocco A. A. Armonda, Preetham Kumar, Benjamin Kenigsberg, Diego Medvedofsky
Summary: This study used speckle tracking echocardiography (STE) to evaluate the differences of neurogenic stunned myocardium (NSM) between acute ischemic stroke (AIS) and aneurysmal subarachnoid hemorrhage (SAH), and found significantly impaired left ventricular (LV) contraction in AIS patients.
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
(2023)
Editorial Material
Clinical Neurology
Odysseas Kargiotis, Klearchos Psychogios, Apostolos Safouris, Athina Andrikopoulou, Andreas Eleftheriou, Stavros Spiliopoulos, Georgios Magoufis, Georgios Tsivgoulis
Article
Medicine, General & Internal
Vida Abedi, Clare Lambert, Durgesh Chaudhary, Emily Rieder, Venkatesh Avula, Wenke Hwang, Jiang Li, Ramin Zand
Summary: In this study, electronic health records and data science techniques were used to estimate the optimal cut-point for defining the age of young ischemic stroke. By analyzing patient similarity, clinical profiles, and comorbidity patterns, the optimal age for young stroke was determined to be 54 years for women and 52 years for men. These findings can provide guidance for clinical diagnosis and treatment of stroke.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Aristeidis H. Katsanos, Abhilekh Srivastava, Demetrios J. Sahlas, Kanjana Perera, Kelvin K. H. Ng, Raed A. Joundi, Brian Van Adel, Ramiro Larrazabal, Kanchana Ratnayake, Georgios Tsivgoulis, Oscar Benavente, Robert Hart, Mukul Sharma, Ashkan Shoamanesh, Luciana Catanese
Summary: TCD can identify patients at risk of HT following successful EVT. TCD could serve as an inexpensive ancillary test to guide participant selection for clinical trials targeting postprocedural reperfusion injury.
JOURNAL OF NEUROIMAGING
(2023)
Review
Clinical Neurology
Lina Palaiodimou, Amrou Sarraj, Apostolos Safouris, Georgios Magoufis, Robin Lemmens, Else Charlotte Sandset, Guillaume Turc, Marios Psychogios, Georgios Tsivgoulis
Summary: This study conducted a systematic review and meta-analysis, finding that endovascular treatment (EVT) can significantly reduce disability, improve independent ambulation, and lead to good functional outcomes for large-core acute ischaemic stroke (AIS). However, it has no significant impact on excellent functional outcomes and carries a risk of intracranial hemorrhage. Overall, EVT is effective and safe for large-core AIS.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Review
Medicine, General & Internal
Lina Palaiodimou, Georgia Papagiannopoulou, Aristeidis H. Katsanos, Andreas Eleftheriou, Theodore Karapanayiotides, Panayiotis D. Mitsias, Robin Lemmens, Carlos A. Molina, Andrei Alexandrov, Valeria Caso, Ashkan Shoamanesh, Mukul Sharma, Georgios Tsivgoulis
Summary: Despite preventive measures, stroke rates remain high in the primary and secondary prevention settings. Factor XIa inhibition may offer a novel, safe and effective antithrombotic option for stroke prevention. However, the results of this meta-analysis showed that treatment with factor XIa inhibitors did not reduce the risk of ischemic stroke compared to controls.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Aikaterini Theodorou, Lina Palaiodimou, Georgia Papagiannopoulou, Odysseas Kargiotis, Klearchos Psychogios, Apostolos Safouris, Eleni Bakola, Maria Chondrogianni, Vasiliki Kotsali-Peteinelli, Konstantinos Melanis, Athanasios Tsibonakis, Elissavet Andreadou, Sofia Vasilopoulou, Stefanos Lachanis, Georgios Velonakis, Elias Tzavellas, John S. Tzartos, Konstantinos Voumvourakis, Georgios P. Paraskevas, Georgios Tsivgoulis
Summary: This study aimed to assess the prevalence of baseline characteristics, clinical and radiological findings, and outcomes among patients with cerebral amyloid angiopathy (CAA) in Greece. The results showed that focal neurological deficits, cognitive decline, and transient focal neurological episodes were the most common clinical manifestations, while hemorrhagic lesions were the most prevalent neuroimaging findings.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Panagiotis Plomaritis, Aikaterini Theodorou, Vasiliki Michalaki, Maria-Ioanna Stefanou, Lina Palaiodimou, Georgia Papagiannopoulou, Vasiliki Kotsali-Peteinelli, Marianna Bregianni, Elissavet Andreadou, Georgios P. Paraskevas, Sotirios Giannopoulos, Georgios Tsivgoulis, Anastasios Bonakis
Summary: The study aimed to evaluate the prevalence and severity of PLMS in acute stroke patients, and to clarify the association between PLMS and coexisting SDB. The results showed that PLMS were common and mostly severe in acute stroke patients, and had a significant impact on stroke outcomes. Therefore, early detection and treatment of PLMS are important for stroke patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Letter
Clinical Neurology
Marianna Papadopoulou, Eleni Bakola, Apostolos Papapostolou, Maria-Ioanna Stefanou, Elisabeth Andreadou, Vasiliki Zouvelou, Maria Stefanatou, Mina Gaga, Ioannis Michopoulos, Georgios Tsivgoulis
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS
(2023)
Review
Clinical Neurology
Athina-Maria Aloizou, Lina Palaiodimou, Dimitra Aloizou, Efthimios Dardiotis, Ralf Gold, Georgios Tsivgoulis, Christos Krogias
Summary: Cancer-related stroke (CRS) is a clinical challenge with high recurrence and mortality rates. There are limited recommendations for CRS management. This comprehensive overview collects and summarizes studies on acute reperfusion and secondary prevention treatments for cancer patients with ischemic stroke, focusing on antithrombotic agents. The findings suggest that acute reperfusion is generally safe, but functional outcomes are often poor. Anticoagulation is necessary for many patients, with low-molecular weight heparins being the treatment of choice. Other targeted treatments and conventional cerebrovascular risk factors should also be considered. Urgent randomized-controlled clinical trials are needed to determine the most effective management options.
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS
(2023)
Article
Clinical Neurology
Wendy Dusenbury, Marc D. Malkoff, Peter D. Schellinger, Martin Koehrmann, Adam S. Arthur, Lucas Elijovich, Andrei V. Alexandrov, Georgios Tsivgoulis, Anne W. Alexandrov
Summary: This study aimed to investigate the beliefs and practices of clinicians regarding head positioning in patients with hyperacute intracerebral hemorrhage (ICH). The results of the survey showed that there is no consensus among clinicians on the optimal head position for these patients, and they remain unconvinced by previous research findings. Further research is needed to examine the effects of head positioning on clinical outcomes in hyperacute ICH.
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS
(2023)
Article
Neurosciences
Adam Vacek, Grant Mair, Philip White, Philip M. Bath, Keith W. Muir, Rustam Al-Shahi Salman, Chloe Martin, David Dye, Francesca M. Chappell, Ruediger von Kummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw
Summary: This study evaluated the performance of e-ASPECTS software in delineating the extent of intracranial hemorrhage (ICH) on brain CT scans. The results showed that the software achieved excellent or good delineation of ICH extent in 71% of cases. However, it was more likely to over- or under-estimate the extent when ICH was more extensive, intraventricular, or extra-axial.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Mathias Jacobsen Bach, Audrone Jakubauskaite, Ian Law, Otto Molby Henriksen, Inger Havsteen, Alexander Cuculiza Henriksen, Sverre Rosenbaum, Lisbeth Marner
Summary: This study found that the rCBFacz value after ACZ challenge can serve as an important indicator for predicting future cerebrovascular events, with high accuracy and prognostic value.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Tak Kyu Oh, Saeyeon Kim, In-Ae Song
Summary: The study found that many survivors of nontraumatic intracranial hemorrhage in South Korea experience unemployment, decreased household income, and newly acquired disability after intensive care unit admission. However, these changes are not associated with 2-year all-cause mortality.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Eduardo Sousa de Melo, Rodrigo de Paiva Bezerra, Arthur Cesario de Holanda, Maria Junia Lira e Silva, Paloma Peter Travassos, Tayne Fernanda Lemos da Silva, Genova Maria de Azevedo Oliveira, Silvia Marinho Martins Alves, Carolina de Araujo Medeiros, Maria das Neves Dantas da Silveira Barros, Wilson Alves de Oliveira, Gisele Sampaio Silva, Luciana Patrizia Alves de Andrade Valenca
Summary: Cardiac involvement has been found to be the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors are prevalent, their influence on ischemic stroke in Chagas disease appears limited.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Pingping Zheng, Ning Zhang, Zixi Chen
Summary: This case presents a rare infectious cause of stroke and air embolism involving a pulmonary abscess and pulmonary vein thrombosis. Early detection, diagnosis, and appropriate treatment of infected systemic embolism in young patients are crucial to prevent serious complications.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Filippo Luca Gurgoglione, Luigi Vignali, Maria Alberta Cattabiani, Emilia Solinas, Giorgio Benatti, Iacopo Tadonio, Federico Barocelli, Chiara Dizdari, Domenico Tuttolomondo, Diego Ardissino, Francesco Nicolini, Giampaolo Niccoli
Summary: The incidence of recurrent ischemic neurological events after transcatheter patent foramen ovale closure is relatively low. Obesity, Risk of Paradoxical Embolism score < 7, and migraine are independent positive predictors of recurrent stroke or transient ischemic attack.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Angelo Cascio Rizzo, Ghil Schwarz, Amedeo Cervo, Giuditta Giussani, Chiara Ceresa, Antonella Gatti, Fausto De Angeli, Cristina Motto, Angelo Guccione, Rachele Tortorella, Giuseppe Granata, Claudia Rollo, Antonio Macera, Mariangela Piano, Guglielmo Pero, Elio Clemente Agostoni
Summary: This study aimed to evaluate the efficacy and safety of endovascular treatment (EVT) in primary and EVT-induced secondary medium-vessel occlusions (MeVO). The results showed that primary MeVO had poorer outcomes in terms of complications, EVT efficacy, and the proportion of patients with a modified Rankin Scale (mRS) of 0-2 at 3 months compared to exclusive large-vessel occlusion (LVO). However, EVT-induced secondary MeVO showed similar safety and efficacy outcomes as exclusive LVO and had better outcomes in terms of mRS 0-2 compared to primary MeVO.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jing Zhang, Chenming Wei, Jian Wu
Summary: This case report describes a patient with Bloom syndrome who developed acute cerebral infarction along with elevated antiphospholipid antibodies, suggesting a possible association between immune and coagulation abnormalities caused by Bloom syndrome and the development of acute cerebral infarction.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Yunxia Zhou, Shenglan He, Yanhong Hu
Summary: Compared with clopidogrel, DAPT with ticagrelor plus aspirin was associated with significantly lower thromboembolic events without an increase in hemorrhagic events in the treatment of intracranial aneurysms, according to the one-year clinical outcome analysis. However, larger upcoming trials are needed to confirm the effectiveness and safety of ticagrelor-associated DAPT.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Edvania Andrade de Moura Silva, Ludmilla Ribeiro Batista, Marcela Aline Fernandes Braga, Luci Fuscaldi Teixeira-Salmela, Christina Danielli Coelho de Morais Faria, Iza Faria-Fortini
Summary: The study found that stroke severity is the best predictor of self-perceived manual ability at both three and six months after stroke. Age, although significant, contributes little to the prediction of manual ability.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Sidarrth Prasad, Erica M. Jones, Mehari Gebreyohanns, Veronica Aguilera, DaiWai M. Olson, Jane A. Anderson, Sean I. Savitz, Salvador C. Flores, Steven J. Warach, Charlotte E. Rhodes, Mark P. Goldberg, Nneka L. Ifejika
Summary: This study identified the barriers and facilitators to adopting tenecteplase (TNK) as a thrombolytic treatment for acute ischemic stroke (AIS) by conducting qualitative research with stroke clinicians in Texas. The findings suggest that providing evidence and identifying key change processes can help clinicians achieve consensus on adopting TNK for AIS treatment.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jeshma Jayan, Sunil K. Narayan, Yasmin Nesha Haniffa, Navin Kumar
Summary: This study investigated the effects of transcranial electrical and magnetic stimulation on somatosensory evoked potentials in chronic ischemic stroke patients, finding that the real tDCS and rTMS combination results in significant improvement and is safe for use.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Phoebe M. Tran, Cenjing Zhu, William T. Harris II, Sajeesh K. Kamala Raghavan, Agricola Odoi, Liem Tran
Summary: This study assessed the geographic accessibility of stroke rehabilitation facilities in Tennessee. The study found that rural counties had significantly longer travel distances and times compared to urban counties. Counties with high and medium stroke prevalence also had higher travel times and distances compared to low stroke prevalence counties. Therefore, addressing transportation barriers and implementing tele-rehabilitation are crucial for improving access to stroke aftercare in these areas.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Lili Xu, Shuaiyu Chen, Jing Xu, Yanyan Shi, Zhihang Huang, Meng Wang, Ziqiao Wei, Hui Cao, Junshan Zhou, Wei Wang, Mingyang Du
Summary: This study found that the Chinese Visceral Adiposity Index (CVAI) is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after endovascular thrombectomy (EVT).
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Guangying Wu, Shuhua Li, Min Luo, Xiaotian Li, Xinghua Zhu, Junhuai Zhang, Qian He, Qian Yang, Guojiang Zhao, Shasha Luo, Zhijie Yang
Summary: The study aimed to investigate the relationship between serum alkaline phosphatase (ALP) levels and the severity and prognosis of intracerebral hemorrhage (ICH). The results showed that serum ALP levels in ICH patients were significantly elevated and correlated with hematoma volume and Glasgow coma scale (GCS) score. High serum ALP levels may serve as a potential predictor for the severity and unfavorable prognosis of ICH.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)