First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288

A Randomized Trial to Assess the Efficacy and Safety of ABT-126, a Selective α7 Nicotinic Acetylcholine Receptor Agonist, in the Treatment of Cognitive Impairment in Schizophrenia

(2016) George M. Haig et al.   AMERICAN JOURNAL OF PSYCHIATRY

Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors reverse ketamine-induced schizophrenia-like deficits in rats

(2016) Agnieszka Nikiforuk et al.   NEUROPHARMACOLOGY

Positive allosteric modulation of alpha 7 nicotinic acetylcholine receptors enhances recognition memory and cognitive flexibility in rats

(2015) Agnieszka Nikiforuk et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Randomized, Double-Blind, Placebo-Controlled Study of Encenicline, an α7 Nicotinic Acetylcholine Receptor Agonist, as a Treatment for Cognitive Impairment in Schizophrenia

(2015) Richard SE Keefe et al.   NEUROPSYCHOPHARMACOLOGY

α7-Nicotinic Acetylcholine Receptor Agonists for Cognitive Enhancement in Schizophrenia

(2013) Robert Freedman   Annual Review of Medicine

A Randomized Exploratory Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) for Cognitive Enhancement in Schizophrenia

(2013) Jeffrey A Lieberman et al.   NEUROPSYCHOPHARMACOLOGY

Short-Term Tropisetron Treatment and Cognitive and P50 Auditory Gating Deficits in Schizophrenia

(2012) Xiang Yang Zhang et al.   AMERICAN JOURNAL OF PSYCHIATRY

Allosteric alpha-7 nicotinic receptor modulation and P50 sensory gating in schizophrenia: A proof-of-mechanism study

(2012) Georg Winterer et al.   NEUROPHARMACOLOGY

Differential Immediate and Sustained Memory Enhancing Effects of Alpha7 Nicotinic Receptor Agonists and Allosteric Modulators in Rats

(2011) Morten S. Thomsen et al.   PLoS One

Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: Results from the Consortium on Genetics of Schizophrenia

(2010) Ann Olincy et al.   SCHIZOPHRENIA RESEARCH

Positive allosteric modulation of α7 neuronal nicotinic acetylcholine receptors: lack of cytotoxicity in PC12 cells and rat primary cortical neurons

(2009) Min Hu et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Role of Age, Gender, Education, and Intelligence in P50, N100, and P200 Auditory Sensory Gating

(2009) Marijn Lijffijt et al.   JOURNAL OF PSYCHOPHYSIOLOGY

Initial Phase 2 Trial of a Nicotinic Agonist in Schizophrenia

(2008) Robert Freedman et al.   AMERICAN JOURNAL OF PSYCHIATRY